Results 91 to 100 of about 2,284,312 (360)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Acculturative Stress and Latino Depression: The Mediating Role of Behavioral and Cognitive Resources [PDF]
, 2013 Although research has found that acculturative stress is significantly associated with adverse psychological adjustment among Latinos, the mechanism by which this relationship exists is not clearly understood. The purpose of this study was to investigate
Driscoll, Mark W., Torres, Lucas
core +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Modeling Infection with Multi-agent Dynamics [PDF]
, 2012 Developing the ability to comprehensively study infections in small populations enables us to improve epidemic models and better advise individuals about potential risks to their health.
J. Stehle +4 more
core +2 more sources
Research Progress in the Early Warning of Chicken Diseases by Monitoring Clinical Symptoms [PDF]
, 2022 Pengguang He +6 more
openalex +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Gender inequalities and depression [PDF]
, 2015 More gender-equal societies promote better mental health among both men and women and reduce the gender gap in depressive ...
Bracke, Piet +2 more
core
Are lay people good at recognising the symptoms of schizophrenia? [PDF]
, 2013 ©2013 Erritty, Wydell. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
AF Jorm +35 more
core +2 more sources
Association between Contact with Nature and Anxiety, Stress and Depression Symptoms: A Primary Survey in Brazil [PDF]
, 2022 Adriano Bressane +7 more
openalex +1 more source