Results 61 to 70 of about 1,402,226 (290)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Longitudinal Changes in Symptom Cluster Membership in Inflammatory Bowel Disease [PDF]
, 2018 Purpose: To describe changes in symptom cluster membership over 1 year and to examine which demographic and clinical factors predict changes in symptom cluster membership among adults with inflammatory bowel disease.
Jeon, S +4 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec +6 more
wiley +1 more source
Scientific ReportsThe aim of this study was to investigate the incidence of symptoms in patients after anterior cervical spine surgery, to construct a symptom network, identify core symptoms and symptom clusters, and provide a theoretical basis for specified symptom ...
Yao-jing Ma +9 more
doaj +1 more source
Exploring symptom clusters in Chinese patients with peritoneal dialysis: a network analysis
Renal FailureBackground In recent years, the research on symptom management in peritoneal dialysis (PD) patients has shifted from a single symptom to symptom clusters and network analysis.
Di-fei Duan +14 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk +10 more
wiley +1 more source
Frontiers in MedicineBackgroundChronic fatigue syndrome is characterized by multiple co-occurring physical, cognitive, sleep, and emotional symptoms. Traditional symptom cluster analysis identifies patterns of symptom co-occurrence but does not clarify the relative ...
Aiqun Zi +5 more
doaj +1 more source
BMC Cancer, 2019 Background Chemotherapy-induced peripheral neuropathy (CIPN) is common among cancer patients treated with neurotoxic chemotherapy agents. Better knowledge on symptom clusters of CIPN may help improve symptom management in clinical practice.
Mian Wang +5 more
doaj +1 more source
Exploring symptom clusters in people with chronic kidney disease [PDF]
, 2017 Chronic kidney disease is associated with a high symptom burden that is strongly linked to poor individual outcomes and quality of life. The complex relationships among these symptoms remain poorly understood. This study was the first to identify symptom
Al Mutary, Hayfa Hamed A.
core +1 more source