Results 71 to 80 of about 4,332,955 (318)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Factors contributing to the time taken to consult with symptoms of lung cancer: a cross-sectional study [PDF]

, 2009
<b>Objectives</b>: To determine what factors are associated with the time people take to consult with symptoms of lung cancer, with a focus on those from rural and socially deprived areas.
Ziebland, S.B., Raja, A, Ziebland, Susan, Duff, EM, MacLeod, U., Ziebland, S. B., Wyke, S, Lee, A. J., Smith, SM, Nicolson, MC, Smith, S.M., Wyke, S., Campbell, N. C., Duff, E.M., Ritchie, L. D., Campbell, N.C., Nicolson, M.C., Lee, AJ, Lee, A.J., Nicolson, M. C., Smith, S. M., Duff, E. M., Ritchie, L.D., Raja, A., MacLeod, U, Ritchie, LD, Campbell, NC   +26 more
core   +1 more source

Clinical manifestations and long-term symptoms associated with SARS-CoV-2 omicron infection in children aged 0–17 years in Beijing: a single-center study

Frontiers in Pediatrics
ObjectiveThe study aims to analyze the clinical characteristics of acute phase of SARS-CoV-2 infection in children aged 0–17 years with the Omicron variant, and summarize the persistent symptoms or new-onset clinical manifestations from 4 to 12 weeks ...
Jing Li, Jingjing Li, Ling Cao, Lin Wang, Xiaobo Chen, Wenquan Niu, Li Dang, Shuzhi Dai, Ying Wang, Menglei Ge, Weijie Liu, Qinwei Song, Wenjian Xu, Lijuan Ma   +13 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Somatic symptoms of generalized anxiety disorder from the DSM-IV: Associations with pathological worry and depression symptoms in a nonclinical sample [PDF]

, 1999
The present study investigates specificity of the six somatic symptoms that are associated with generalized anxiety disorder (GAD), according to the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders.
Joormann, Jutta, Stoeber, Joachim, Joachim Stöber, Jutta Joormann   +3 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Occupational Respiratory Health Symptoms and Associated Factors Among Street Sweepers in Ilala Municipality [PDF]

, 2012
Street working environment condition particularly exposed to organic and inorganic dust and chronic inhalation of dust during street sweeping may associated with increases in respiratory health symptoms among street sweepers.
Stambuli, P., Stambuli, Prisca
core  

Tailoring a cognitive behavioural model for unexplained physical symptoms to patient's perspective: a bottem-up approach.

, 2010
The prevalence of unexplained physical symptoms (UPS) in primary care is at least 33%. Cognitive behavioural therapy has shown to be effective. Within cognitive behavioural therapy, three models can be distinguished: reattribution model, coping model and
Zonneveld, L.N., van 't Spijker, A, Duivenvoorden, Hugo, Zonneveld, L.N.L. (Lyonne), Passchier, Jan, Spijker, A van 't, Spijker, A. (Adriaan) van 't, Spijker, Adriaan, Duivenvoorden, H.J. (Hugo), Passchier, J., Zonneveld, Lyonne, Passchier, J. (Jan), Duivenvoorden, H.J.   +12 more
core   +1 more source

Digital tools and self-administered home blood tests: A convergent mixed methods pilot study

Digital Health
Background Digital tools and self-administered home blood tests offer a flexible approach to research data collection, biological sample management, and informed consent but require evaluation in relevant study settings.
Lana Hebib, Emelie Gustafson Hedov, Maria Storgärds, Peder af Geijerstam, Marie Löf, Jason HY Wu, Lisa Kastbom, Karin Rådholm   +7 more
doaj   +1 more source

Symptoms? Which Symptoms? Distorted Symptom Presentation and Its Detection

In this chapter, we elaborated on the two main forms of distorted symptom reporting: symptom over- and underreporting. In certain situations, individuals might exaggerate their symptoms. For instance, defendants facing legal issues may overstate their mental health problems.
Merckelbach, Harald, Boškovic, Irena
openaire   +1 more source