Results 81 to 90 of about 4,332,955 (318)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

The role of Phytoestrogens in the management of menopausal symptoms [PDF]

open access: yes, 2012
Menopause reflects a change in the woman’s physiological hormonal status and is regarded as a pivotal point in a woman’s life. The commonest symptoms experienced by women during the menopause are hot flushes and night sweats.
Avendonk, Tania van
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Professional guide to signs and symptoms

open access: yes, 2007
ix.870hal.;14 ...
symptoms
core  

Impact of prenatal depressive symptoms on postpartum depressive symptoms: Mediation effect of perinatal health

open access: yes, 2018
To analyze the mediation effect of perinatal health on the association between prenatal depressive symptoms and postpartum depressive symptoms 180 women filled the Edinburgh Postnatal Depressive Scale (EPDS) at 35 weeks of gestation and two months after ...
Costa, Raquel, Silva, Fábio, Conde, Ana
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Prospective study of symptoms of ovarian cancer in postmenopausal women

open access: yes, 2010
Background: Research has identified key symptoms of ovarian cancer, although there are gaps in the knowledge about the pattern of symptom onset, severity and frequency. Previous studies are limited by use of non-validated questionnaires, recall bias and
Allen, P.L.
core  

Physical appearance perfectionism explains variance in eating disorder symptoms above general perfectionism [PDF]

open access: yes, 2015
Physical appearance perfectionism is a domain-specific form of perfectionism comprising two components: hope for perfection and worry about imperfection (Yang & Stoeber, 2012).
Stoeber, Joachim, Yang, Hongfei
core   +1 more source

Reproducible microbiome composition signatures of anxiety and depressive symptoms

open access: yes, 2023
The gut microbiome is a significant contributor to mental health, with growing evidence linking its composition to anxiety and depressive disorders.
Eamonn Ferguson   +22 more
core   +1 more source

The Effects of Paeonia lactiflora Pall. and Astragalus Membranaceus Single Extracts on Bone Metabolic Profile in Ovariectomized Mice

open access: yesClinical and Experimental Obstetrics & Gynecology
Background: Metabolic bone disease, associated with estrogen deficiency, is common condition in postmenopausal women. Paeonia lactiflora Pall. (PL) and Astragalus membranaceus (AM) have been known to have estrogenic activity and to improve postmenopausal
Min Jung Park   +7 more
doaj   +1 more source

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