Results 81 to 90 of about 4,802,356 (261)

An Estimate of the proportion of symptoms reported in Self-administered questionnaires that are captured as adverse drug events in an observational database [PDF]

, 2007
Purpose: This study was conducted to determine how frequently self-reported symptoms are captured as adverse drug events (ADEs) during chart abstraction.
Walmsley, S., Raboud, J., Bayoumi, A., Phillips, E.J., Sterling, S., Lesosky, M.   +5 more
core  

The classification and nomenclature of 'medically unexplained symptoms': conflict, performativity and critique [PDF]

, 2012
Medically unexplained symptoms – including the many syndromes that fall under this umbrella – involve a discrepancy between professional knowledge and lay experience and are often associated with latent or explicit dynamics of conflict.
Greco, Monica
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

The Effects of Paeonia lactiflora Pall. and Astragalus Membranaceus Single Extracts on Bone Metabolic Profile in Ovariectomized Mice

Clinical and Experimental Obstetrics & Gynecology
Background: Metabolic bone disease, associated with estrogen deficiency, is common condition in postmenopausal women. Paeonia lactiflora Pall. (PL) and Astragalus membranaceus (AM) have been known to have estrogenic activity and to improve postmenopausal
Min Jung Park, Cha Soon Kim, Ki-Tae Ha, Ju-Hwa Baek, Hyewon Cho, Youngeun Lee, Chang-Woon Kim, Bo Sun Joo   +7 more
doaj   +1 more source

GASTROINTESTINAL SYMPTOMS IN INFANCY: A POPULATION-BASED PROSPECTIVE STUDY

, 2005
BACKGROUND: During the first months of life, infants can suffer from many 'minor' gastroenterological disturbances. However, little is known about the frequency of these problems and the factors which predispose or facilitate their onset. AIMS: (a) To
INDINNIMEO, L, D. D’Amico, AVERNA, Maurizio, R. Merolla, L. Di Prima, D'AMICO, D, L. Indinnimeo, G. Iacono, A. Carroccio, CARROCCIO, Antonio, SCALICI, C, IACONO, G, MEROLLA, R, CAVATAIO, Francesca, M.R. Averna, DI PRIMA, Lidia, BONCI, Enea, F. Cavataio, INDINNIMEO, Luciana, M. R. Averna, BONCI, E, E. Bonci, C. Scalici, I. N. Infancy The Paediatric Study Group On Gastrointestinal Symptoms, D. D'Amico   +24 more
core   +1 more source

Stroke patients' interpretation of symptoms and presentation to hospital [PDF]

, 2013
The aim of this study was to elucidate patient interpretation of stroke symptoms and to investigate factors which influence timely presentation to hospital. Methods: All patients admitted to Mater Dei Hospital with a diagnosis of cerebrovascular accident
Aquilina, Simon, Gruppetta, Mark, Scicluna, Gabrielle, Theuma, Francesca, Aquilina, Josanne, Mallia, Maria   +5 more
core   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

The role of Phytoestrogens in the management of menopausal symptoms [PDF]

, 2012
Menopause reflects a change in the woman’s physiological hormonal status and is regarded as a pivotal point in a woman’s life. The commonest symptoms experienced by women during the menopause are hot flushes and night sweats.
Avendonk, Tania van
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Characterization of COVID-19 cases in the formal and informal settlements in Dagoretti sub-county Kenya, 2020

Journal of Interventional Epidemiology and Public Health
Introduction: COVID-19 posed a serious public health threat to all ages. In Kenya, it was first detected on March 13, 2020, in its capital - Nairobi, which remained the epicenter of the disease thereafter. Dagoretti is one area that has both formal and
Florence Wanjiru Mugo, Ahmed Abade Mohamed, Peter Kabetu Njenga, Maurice Owiny, Fredrick Odhiambo   +4 more
doaj   +1 more source