Results 101 to 110 of about 4,332,955 (318)

Stroke patients' interpretation of symptoms and presentation to hospital [PDF]

, 2013
The aim of this study was to elucidate patient interpretation of stroke symptoms and to investigate factors which influence timely presentation to hospital. Methods: All patients admitted to Mater Dei Hospital with a diagnosis of cerebrovascular accident
Aquilina, Simon, Gruppetta, Mark, Scicluna, Gabrielle, Theuma, Francesca, Aquilina, Josanne, Mallia, Maria   +5 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

[The symptoms in family medicine are not symptoms of disease, they are symptoms of life].

Atencion primaria, 2012
The symptoms in family medicine are not signs of disease, but "signs of life"; in the consultation "all patient life comes together with him". Every consultation is primarily a biopsicosocial problem: the person perceives a dysfunction or alteration in relation with himself and his context.
José Luis, Turabián, Benjamín, Pérez Franco, José Luis, Turabián Fernández, Benjamin, Pérez Franco   +3 more
openaire   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Depressive symptoms are associated with analgesic use in people with Alzheimer's disease: Kuopio ALSOVA study.

, 2015
Neuropsychiatric symptoms of Alzheimer's disease (AD) such as depression may be associated with pain, which according to the literature may be inadequately recognized and managed in this population.
Eija Lönnroos, Soili Törmälehto, Janne Martikainen, Lönnroos, E, Saku Väätäinen, Hallikainen, I, ALSOVA Study Group, ., Ilona Hallikainen, Anne M Koivisto, Väätäinen, S, ALSOVA Study Group, Bell, JS, Lotta Salo, Salo, L, Martikainen, J, Törmälehto, S, Koivisto, AM, Gilmartin, JF, Julia Fiona-Maree Gilmartin, J Simon Bell   +19 more
core   +1 more source

Dust Exposure and Chronic Respiratory Symptoms Among Coffee Curing Workers in Kilimanjaro: A Cross Sectional Study. [PDF]

, 2011
Coffee processing causes organic dust exposure which may lead to development of respiratory symptoms. Previous studies have mainly focused on workers involved in roasting coffee in importing countries.
Bråtveit, Magne, Sakwari, Gloria, Mamuya, Simon H D, Moen Bente E, Bente E Moen, Moen, Bente E, Sakwari Gloria, Mamuya Simon HD, Moen, Bente E., Simon HD Mamuya, Magne Bråtveit, Bråtveit Magne, Mamuya, Simon H. D., Gloria Sakwari   +13 more
core   +1 more source

SyMptOMS Mobile App for Exposure Therapy -- SyMptOMS-ET

, 2022
<p>The SyMptOMS Mobile App has been designed to support psychological treatment. It develops its full potential when used in a blended format. Currently, it supports the treatment of anxiety disorders where the emotional response is exacerbated in ...
Alberto González-Pérez, Miguel Matey-Sanz   +1 more
core   +1 more source

Profile of the subtypes of angle closure glaucoma in a tertiary hospital in North India

Indian Journal of Ophthalmology, 1998
A prospective study of 500 consecutive patients of primary angle closure glaucoma was undertaken to study the clinical profile of the three subtypes: acute, subacute, and chronic.
Sihota Ramanjit, Agarwal H
doaj  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source