Results 101 to 110 of about 6,338,781 (311)

Profile of the subtypes of angle closure glaucoma in a tertiary hospital in North India

open access: yesIndian Journal of Ophthalmology, 1998
A prospective study of 500 consecutive patients of primary angle closure glaucoma was undertaken to study the clinical profile of the three subtypes: acute, subacute, and chronic.
Sihota Ramanjit, Agarwal H
doaj  

Depressive symptoms and quality of life in people with age-related macular degeneration [PDF]

open access: yes, 2011
Purpose: To examine quality of life and associated factors in people with Age-Related Macular Degeneration (AMD). Methods: One hundred and forty-five AMD participants (mean age 78.0 +/- 7.7 years) and 104 age- and gender- matched controls (mean age 78.1 +
Mathew, Remy Sheena   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

EFFECTIVENESS OF TRIMEBUTINE MALEATE FOR COMPREHENSIVE TREATMENT OF CHRONIC PANCREATITIS IN CHILDREN

open access: yesПедиатрическая фармакология, 2014
Relevance. Pancreatic pathology is often observed in children, especially in adolescents. Timely adequate therapy helps to reduce duration of hospitalization and, possibly, prevent future relapses.
I. S. Lembrik
doaj   +1 more source

Personal constructs of mind-body identity in people who experience medically unexplained symptoms (MUS) [PDF]

open access: yes, 2018
"Medically unexplained symptoms" (MUS) refers to chronic physical symptoms without a clear medical cause, which produce significant levels of distress and functional impairment.
Payne, Helen   +2 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Synbiotics in Oncology: A Scoping Review Protocol on Their Impact and Outcomes in Cancer Care

open access: yesNursing Reports
Symptom management remains challenging in cancer care. Emerging from nutritional science, nutritional metabolomics has seen exponential growth over recent years, aiming to discern the relationship between dietary habits and health consequences.
Silvia Belloni   +7 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Security of attachment and adolescents' depression [PDF]

open access: yes, 2017
Objectives: The purpose of the study was to investigate the role of internal working models in the prediction of depression. Insecure attachment has been theorized to form a vulnerability factor for the emergence of depressive symptoms.
Wendołowska, Anna
core  

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