Results 131 to 140 of about 449,578 (382)
An NMDA Receptor-Dependent Mechanism Underlies Inhibitory Synapse Development
Cell Reports, 2016 In the mammalian brain, GABAergic synaptic transmission provides inhibitory balance to glutamatergic excitatory drive and controls neuronal output. The molecular mechanisms underlying the development of GABAergic synapses remain largely unclear. Here, we
Xinglong Gu, Liang Zhou, Wei Lu
doaj +1 more source
Glial Contribution to Excitatory and Inhibitory Synapse Loss in Neurodegeneration
Frontiers in Cellular Neuroscience, 2019 Synapse loss is an early feature shared by many neurodegenerative diseases, and it represents the major correlate of cognitive impairment. Recent studies reveal that microglia and astrocytes play a major role in synapse elimination, contributing to ...
C. Henstridge +2 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu +7 more
wiley +1 more source
Nature Communications, 2017 If a three-dimensional physical electronic system emulating synapse networks could be built, that would be a significant step toward neuromorphic computing.
Chaoxing Wu +4 more
semanticscholar +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Depolarization-activated potentiation of the T fiber synapse in the blue crab [PDF]
, 1993 The blue crab T fiber synapse, associated with the stretch receptor of the swimming leg, has a nonspiking presynaptic element that mediates tonic transmission.
Lin, J.-W., Llinas, R.
core
THE FUNCTION OF THE PROXIMAL SYNAPSES OF THE SQUID STELLATE GANGLION [PDF]
, 1959 S. H. Bryant
openalex +1 more source
Microglia Enhance Synapse Activity to Promote Local Network Synchronization
eNeuro, 2018 Visual Abstract Microglia are highly motile immunoreactive cells that play integral roles in the response to brain infection and damage, and in the progression of various neurological diseases.
Ryohei Akiyoshi +10 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Janus (MoS2) transistors functionalized with sodium alginate (SA) and poly(vinylidene fluoride‐co‐trifluoroethylene) [P(VDF‐TrFE)] exhibit persistent photo‐induced ionic gating, driven by dynamic cation migration at the hybrid interface. This ionic mechanism enables finely tunable photoconductivity and emulates key synaptic plasticity behaviors ...
Yeonsu Jeong +5 more
wiley +1 more source