Results 161 to 170 of about 449,578 (382)

Immunomodulation With Local, Sustained Delivery of Pituitary Adenylate Cyclase Activating Polypeptide Results in Improved Functional Recovery in Stroke‐Injured Mice

Advanced Healthcare Materials, EarlyView.
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho, David Xinzheyang Li, Hong Cui, Dania Akbar, Ricky Siu, Cindi M. Morshead, David Chatenet, Molly S. Shoichet   +7 more
wiley   +1 more source

Age- and sex-dependency of thrombin generation parameters in the general Italian population: the Moli-sani study

Frontiers in Cardiovascular Medicine
BackgroundRecent developments have made the thrombin generation (TG) test accessible to the clinical laboratory. Therefore, the clinical interpretation of TG parameters has become of increasing interest, and reference values are required.
Simona Costanzo, Bas de Laat, Bas de Laat, Augusto Di Castelnuovo, Lisa van der Vorm, Amalia De Curtis, Chiara Cerletti, Marisa Ninivaggi, Maria Benedetta Donati, Licia Iacoviello, Licia Iacoviello, Romy de Laat-Kremers, the Moli-sani investigators, Licia Iacoviello, Giovanni de Gaetano, Maria Benedetta Donati, Chiara Cerletti, Marialaura Bonaccio, Americo Bonanni, Simona Costanzo, Amalia De Curtis, Augusto Di Castelnuovo, Alessandro Gialluisi, Francesco Gianfagna, Mariarosaria Persichillo, Teresa Di Prospero, Jos Vermylen, Renzo Pegoraro, Antonio Spagnolo, Deodato Assanelli, Livia Rago, Simona Costanzo, Marco Olivieri, Sabatino Orlandi, Teresa Panzera, Augusto Di Castelnuovo, Marialaura Bonaccio, Simona Costanzo, Simona Esposito, Alessandro Gialluisi, Anwal Ghulam, Francesco Gianfagna, Antonietta Pepe, Emilia Ruggiero, Sukshma Sharma, Amalia De Curtis, Concetta Civitillo, Alisia Cretella, Sara Magnacca, Fabrizia Noro, Mariarosaria Persichillo, Francesca Bracone, Fiorella De Rita, Giuseppe Di Costanzo, Sabrina Franciosa, Martina Morelli, Americo Bonanni, Ospedale A. Cardarelli-Campobasso, Ospedale F. Veneziale-Isernia, Ospedale San Timoteo-Termoli, Ospedale Ss. Rosario-Venafro, Ospedale Vietri-Larino, Ospedale San Francesco Caracciolo-Agnone, Casa di Cura Villa Maria-Campobasso   +63 more
doaj   +1 more source

The structures of the glia and of the synapses in the sympathetic chain of man [PDF]

, 1960
Katja Scharenberg
openalex   +1 more source

Complement and microglia mediate early synapse loss in Alzheimer mouse models

Science, 2016
Soyon Hong, Victoria F. Beja-Glasser, Bianca M. Nfonoyim, A. Frouin, Shaoming Li, Saranya Ramakrishnan, Katherine M. Merry, Qiaoqiao Shi, A. Rosenthal, B. Barres, C. Lemere, D. Selkoe, B. Stevens   +12 more
semanticscholar   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

THE FINE STRUCTURE OF INHIBITORY SYNAPSES IN THE CRAYFISH [PDF]

, 1961
R. Price Peterson, Frank A. Pepe
openalex   +1 more source

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

Advanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček   +8 more
wiley   +1 more source

Avoiding fragmentation: The potential of synergistic efforts across the IMI portfolio

Frontiers in Neurology, 2022
Carlos Díaz, Lewis Killin, Nigel Hughes
doaj   +1 more source

Fine Structure of Cell Contact and the Synapse [PDF]

, 1967
Douglas E. Kelly
openalex   +1 more source

Machine‐Learning‐Aided Advanced Electrochemical Biosensors

Advanced Materials, EarlyView.
Electrochemical biosensors are highly sensitive, portable, and versatile. Advanced nanomaterials enhance their performance, while machine learning (ML) improves data analysis, minimizes interference, and optimizes sensor design. Despite progress in both fields, their combined potential in diagnostics remains underexplored.
Andrei Bocan, Roozbeh Siavash Moakhar, Carolina del Real Mata, Max Petkun, Tristan De Iure‐Grimmel, Sripadh Guptha Yedire, Hamed Shieh, Arash Khorrami Jahromi, Sahar Sadat Mahshid, Sara Mahshid   +9 more
wiley   +1 more source