Results 271 to 280 of about 187,009 (324)

Protein Kinase C Activators Enhance Transmission at the Squid Giant Synapse

, 1989
Luis Osses, Susan R. Barry, George J Augustine   +2 more
openalex   +2 more sources

Deficiency of DEK proto‐oncogene alleviates allergic rhinitis by inhibiting RhoA/Ezrin‐mediated mitochondrial fission

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai, Yongde Jin, Jingmei Chai, Jianing Yang, Jiangang Wang, Mu Chen, Liangchang Li, Chongyang Wang, Guanghai Yan   +8 more
wiley   +1 more source

The calcitron: A simple neuron model that implements many learning rules via the calcium control hypothesis. [PDF]

PLoS Comput Biol
Moldwin T, Azran LS, Segev I.
europepmc   +1 more source

Effect of in vivo reprogramming of astrocytes combined with exercise training on neurorepair in rats with spinal cord injury

Animal Models and Experimental Medicine, EarlyView.
Exercise and astrocyte reprogramming synergize to enhance motor function and reduce glial scarring after spinal cord injury, with combined therapies surpassing individual effects. Abstract Background The inability of damaged neurons to regenerate and of axons to establish new functional connections leads to permanent functional deficits after spinal ...
Zuliyaer Talifu, Xin Xu, Huayong Du, Zehui Li, Xiaoxin Wang, Chunjia Zhang, Yunzhu Pan, Han Ke, Wubo Liu, Feng Gao, Degang Yang, Yingli Jing, Yan Yu, Liangjie Du, Jianjun Li   +14 more
wiley   +1 more source

Integrated artificial neurons from metal halide perovskites.

Mater Horiz
de Boer JJ, Ehrler B.
europepmc   +1 more source

Female mice lacking GluA3 show early onset of hearing loss, cochlear synaptopathy, and afferent terminal swellings in ambient sound levels. [PDF]

iScience
Pal I, Bhattacharyya A, V-Ghaffari B, Williams ED, Xiao M, Rutherford MA, Rubio ME.   +6 more
europepmc   +1 more source

Early functional and structural hippocampal impairment in a bilateral common carotid artery stenosis mouse model

Animal Models and Experimental Medicine, EarlyView.
Our study used behavioral tests, laser speckle flowmetry, long‐term potentiation, histochemical staining, molecular experiments, and voxel‐based morphometry to evaluate the hippocampal impairments. It demonstrates early functional and structural impairments in the hippocampus contributing to learning and memory deficits after 1 month of BCAS ...
Ping Tang, Yi Sun, Chunsheng Yang, Nan Zhang   +3 more
wiley   +1 more source

Repetitive concussions promote microglia-mediated engulfment of presynaptic excitatory input associated with cognitive dysfunction. [PDF]

Commun Biol
Chahin M, Mutschler J, Dzhuleva SP, Dieterle C, Jimenez LR, Bhattarai SR, Van Steenbergen V, Bareyre FM.   +7 more
europepmc   +1 more source

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection

Animal Models and Experimental Medicine, EarlyView.
Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam, Md. Ibrahim Khalil Al‐Imran, Mehrukh Zehravi, Sherouk Hussein Sweilam, Mohammad Rakib Mortuza, Jeetendra Kumar Gupta, Thukani Sathanantham Shanmugarajan, Kadirvel Devi, Tanuja Tummala, Mohammed Ali Alshehri, Kalirajan Rajagopal, Mohammed Asiri, Irfan Ahmad, Talha Bin Emran   +13 more
wiley   +1 more source

Noise and Dynamical Synapses as Optimization Tools for Spiking Neural Networks. [PDF]

Entropy (Basel)
Garipova Y, Yonekura S, Kuniyoshi Y.
europepmc   +1 more source