Results 11 to 20 of about 10,302 (256)

Transcriptomic profile of epileptic children treated with ketogenic therapies [PDF]

open access: yesJournal of Integrative Neuroscience, 2022
Background: Ketogenic dietary therapies (KDT) are used as a treatment in childhood epilepsy. However, their mechanism has not yet been established. The main objective of this study was to determine the changes in the transcriptomic profile induced by ...
Jana Ruiz-Herrero   +8 more
doaj   +1 more source

The Absence of Caspase-8 in the Dopaminergic System Leads to Mild Autism-like Behavior

open access: yesFrontiers in Cell and Developmental Biology, 2022
In the last decade, new non-apoptotic roles have been ascribed to apoptotic caspases. This family of proteins plays an important role in the sculpting of the brain in the early stages of development by eliminating excessive and nonfunctional synapses and
I. Suárez-Pereira   +15 more
doaj   +1 more source

Evidence that masking of synapsis imperfections counterbalances quality control to promote efficient meiosis. [PDF]

open access: yesPLoS Genetics, 2013
Reduction in ploidy to generate haploid gametes during sexual reproduction is accomplished by the specialized cell division program of meiosis. Pairing between homologous chromosomes and assembly of the synaptonemal complex at their interface (synapsis ...
Susanna Mlynarczyk-Evans   +2 more
doaj   +1 more source

Regulation of microglia phagocytosis and potential involvement of exercise

open access: yesFrontiers in Cellular Neuroscience, 2022
Microglia are considered the main phagocytic cells in the central nervous system, remodeling neural circuits by pruning synapses during development. Microglial phagocytosis is also a crucial process in maintaining adult brain homeostasis and clearing ...
Congqin Li   +10 more
doaj   +1 more source

The Formation of Bivalents and the Control of Plant Meiotic Recombination

open access: yesFrontiers in Plant Science, 2021
During the first meiotic division, the segregation of homologous chromosomes depends on the physical association of the recombined homologous DNA molecules.
Yared Gutiérrez Pinzón   +3 more
doaj   +1 more source

ASYNAPSIS 1 ensures crossover fidelity in polyploid wheat by promoting homologous recombination and suppressing non-homologous recombination

open access: yesFrontiers in Plant Science, 2023
During meiosis, the chromosome axes and synaptonemal complex mediate chromosome pairing and homologous recombination to maintain genomic stability and accurate chromosome segregation.
Chiara Di Dio   +3 more
doaj   +1 more source

A Compact Fully Electronically Tunable Memristive Circuit Based on CCCDTA with Experimental Results

open access: yesMicromachines, 2023
This work presents a flux-controlled memristor structure employing a Current-Controlled Current Differencing Transconductance Amplifier (CCCDTA) with a grounded capacitor.
Deniz Ozenli
doaj   +1 more source

Peroxisomal Proliferator-Activated Receptor β/δ Deficiency Induces Cognitive Alterations

open access: yesFrontiers in Pharmacology, 2022
Peroxisome proliferator-activated receptor β/δ (PPARβ/δ), the most PPAR abundant isotype in the central nervous system, is involved in microglial homeostasis and metabolism, whose disturbances have been demonstrated to play a key role in memory ...
Triana Espinosa-Jiménez   +33 more
doaj   +1 more source

On the synapsis in amphibia [PDF]

open access: yesProceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character, 1906
Abstract In 1903 and 1904 one of us, in conjunction with Professor Farmer, described the maiotic process in a variety of animals and plants. From the observations then accumulated it was in the first place shown that what we termed the maiotic process appears to be the same throughout the animal and vegetable kingdoms.
J. E. S. Moore, A. L. Embleton
openaire   +1 more source

Meiotic behavior of small chromosomes in maize

open access: yesFrontiers in Plant Science, 2013
The typical behavior of chromosomes in meiosis is that homologous pairs synapse, recombine and then separate at anaphase I. At anaphase II, sister chromatids separate.
James A. Birchler, Fangpu eHan
doaj   +1 more source

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