Results 11 to 20 of about 14,796 (289)
PLoS Genetics, 2021 Meiotic homolog synapsis is essential to ensure accurate segregation of chromosomes during meiosis. In C. elegans, proper regulation of synapsis and a checkpoint that monitors synapsis relies on the spindle checkpoint components, Mad1 and Mad2, and ...
Alice Devigne, Needhi Bhalla
exaly +2 more sources
Chromosome movements in meiotic prophase: regulatory mechanisms and biological roles [PDF]
Frontiers in Cell and Developmental BiologyMeiotic prophase is characterized by dynamic chromosome movements that are essential for accurate genome transmission and the generation of genetic diversity.
Li Zhao, Jinmin Gao, Jinmin Gao
doaj +2 more sources
DNA end configurations dictate synaptic complex formation during NHEJ-mediated end bridging [PDF]
Nature CommunicationsSynapsis, the physical bridging of two broken DNA ends, is a critical step in non-homologous DNA end joining (NHEJ), the primary pathway for repairing DNA double-strand breaks (DSBs) in vertebrates.
Chenyang Zhang +9 more
doaj +2 more sources
All Paired Up with No Place to Go: Pairing, Synapsis, and DSB Formation in a Balancer Heterozygote [PDF]
PLoS Genetics, 2005 The multiply inverted X chromosome balancer FM7 strongly suppresses, or eliminates, the occurrence of crossing over when heterozygous with a normal sequence homolog.
R Scott Hawley, Kim S McKim
exaly +3 more sources
Cells, 2021 Meiosis involves a series of specific chromosome events, namely homologous synapsis, recombination, and segregation. Disruption of either recombination or synapsis in mammals results in the interruption of meiosis progression during the first meiotic ...
Jesús Page +2 more
exaly +3 more sources
, 2018 "Synapsis: A Health Humanities Journal" was founded in 2017 by Arden Hegele, a literary scholar, and Rishi Goyal, a physician. Its mission is to develop conversations among diverse people thinking about medical and humanistic ways of knowing . as a “Department Without Walls” that connects scholars and thinkers from different spheres.
Hegele, Arden
openaire +3 more sources
Dynamics of Rye Chromosome 1R Regions with High or Low Crossover Frequency in Homology Search and Synapsis Development [PDF]
PLoS ONE, 2012 In many organisms, homologous pairing and synapsis depend on the meiotic recombination machinery that repairs double-strand DNA breaks (DSBs) produced at the onset of meiosis.
Nohelia T Valenzuela, Tomás Naranjo
exaly +2 more sources
Somatic Kitl promotes mTOR to facilitate prophase I of meiosis in female embryonic gonads [PDF]
Cell Death and DiseaseHomologous synapsis and recombination are the central events that take place in the prophase I of meiosis. Signaling that promotes the germ cell differentiation and prophase I remains elusive.
Chang Liu +11 more
doaj +2 more sources
PLoS Genetics, 2013 Cohesin subunit SMC1β is specific and essential for meiosis. Previous studies showed functions of SMC1β in determining the axis-loop structure of synaptonemal complexes (SCs), in providing sister chromatid cohesion (SCC) in metaphase I and thereafter, in
Michael Seifert +2 more
exaly +3 more sources
Speedy A governs non-homologous XY chromosome desynapsis as a unique prerequisite for XY loop-axis organization [PDF]
The EMBO JournalIn mouse early pachytene spermatocytes, the X and Y chromosomes undergo rapid non-homologous (NH) synapsis and desynapsis, but the functional significance remains unknown.
Dongteng Liu +18 more
doaj +2 more sources