Results 31 to 40 of about 23,404 (333)

Crossover interference mechanism: New lessons from plants

Frontiers in Cell and Developmental Biology, 2023
Plants are the source of our understanding of several fundamental biological principles. It is well known that Gregor Mendel discovered the laws of Genetics in peas and that maize was used for the discovery of transposons by Barbara McClintock.
Nahid Rafiei, Arnaud Ronceret
doaj   +1 more source

UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells [PDF]

, 2012
The N-end rule pathway is a proteolytic system in which its recognition components (N-recognins) recognize destabilizing N-terminal residues of short-lived proteins as an essential element of specific degrons, called N-degrons.
An, JY, de Rooij, DG, Han, DH, Jang, JM, Kim, BY, Kim, E, Kim, TY, Kwon, YT, Lee, MJ, Lee, YJ, Seo, JW, Yoo, YD, Zakrzewska, A   +12 more
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Cytotoxicity and Effects on the Synapsis Induced by Pure Cylindrospermopsin in an E17 Embryonic Murine Primary Neuronal Culture in a Concentration- and Time-Dependent Manner

Toxins, 2022
Cylindrospermopsin (CYN) is a cyanotoxin whose incidence has been increasing in the last decades. Due to its capacity to exert damage at different levels of the organism, it is considered a cytotoxin.
María G. Hinojosa, Ana I. Prieto, Clara Muñoz-Castro, María V. Sánchez-Mico, Javier Vitorica, Ana M. Cameán, Ángeles Jos   +6 more
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Chromosome Organization in Early Meiotic Prophase

Frontiers in Cell and Developmental Biology, 2021
One of the most fascinating aspects of meiosis is the extensive reorganization of the genome at the prophase of the first meiotic division (prophase I). The first steps of this reorganization are observed with the establishment of an axis structure, that
Corinne Grey, Bernard de Massy
doaj   +1 more source

Defending the genome from the enemy within:mechanisms of retrotransposon suppression in the mouse germline [PDF]

, 2013
The viability of any species requires that the genome is kept stable as it is transmitted from generation to generation by the germ cells. One of the challenges to transgenerational genome stability is the potential mutagenic activity of transposable ...
A Aravin, A Dupressoir, A Dupressoir, A Dupressoir, A Fadloun, A Inagaki, A Inoue, A Inoue, A Meissner, A Prokhortchouk, A Puech, A Sookdeo, A Tsumura, A Vourekas, AA Aravin, AA Aravin, AA Aravin, AA Zabolotneva, AE Peaston, AR Muotri, AR Muotri, B Hendrich, BH Schrans-Stassen, C Chen, C Lu, C Popp, C-X Song, C-X Song, CE Nestor, CG Lian, CM Davis, CP Walsh, D Bourc’his, D Bourc’his, D Branciforte, D Guallar, D Haig, D Lucifero, D Lucifero, D Reiss, D Ribet, D Ribet, D Ribet, D Sproul, D Wolf, D Wolf, DA Kramerov, DC Hancks, DJ Lees-Murdock, DM Maatouk, Donncha S. Dunican, DS Dunican, DT Ting, E Beyret, E Beyret, E Khazina, E Li, EB Chuong, EL Kuff, ES Lander, F Santos, F Yang, FD Araujo, G Hutvagner, G Velasco, GD Evrony, H Cedar, H Cedar, H Heyn, H Kano, H Khan, H Kobayashi, H Stroud, HJ Cooke, HM Rowe, HM Rowe, HM Rowe, I Cantone, I Martín Caballero, I Suetake, IA Maksakova, Ian R. Adams, J Borgel, J Brennecke, J Chen, J Gimenez, J Lange, J Reichmann, J Reichmann, J Rossant, J Sharif, J Xiol, J-H Ng, JA Hackett, JA Hackett, JA Yoder, James H. Crichton, JD Lewis, JK Baillie, JL Garcia-Perez, JL Goodier, JN Athanikar, JO Kriegs, JP Reddington, JP Reddington, JP Thomson, JP Thomson, JV Moran, K Dennis, K Hata, K Hayashi, K Hisada, K Kurimoto, K Myant, K Zheng, K Zheng, KP Koh, L Jackson-Grusby, L Ma, L Piko, L Shen, L-Q Sun, LK Hutnick, M Abe, M Chotalia, M Denne, M Dewannieux, M Dewannieux, M Dewannieux, M Freitag, M Kaneda, M Kaneda, M Ko, M Ko, M Leeb, M Okano, M Reuter, M Reuter, M Ruggiu, M Saitou, M Shoji, M Tachibana, M Tahiliani, M Weber, M Wiench, M Xu, MA Carmell, Marie MacLennan, MC Ward, MM Dawlaty, MM Dawlaty, MM Karimi, MT Romanish, N Bannert, N Gilbert, N Lane, N Mathioudakis, N Reynolds, N Yang, N Zamudio, OH Tam, P Hajkova, P Hajkova, PJ Skene, Q Feng, Q Yan, R Brunmeir, R Burdick, R Fuente De La, R Illingworth, R Lister, R Rebollo, R Shukla, R Yaman, R Öllinger, RH Waterston, Richard R. Meehan, RJ DeBerardinis, RJA Frost, RR Meehan, S Chuma, S Fazio De, S Guibert, S Ito, S Ito, S Kagiwada, S Kaufmann, S Kuntz, S Kuramochi-Miyagawa, S Kuramochi-Miyagawa, S Kuramochi-Miyagawa, S Kuramochi-Miyagawa, S Mi, S Milutinovic, S Salle La, S Schütt, S Seisenberger, S Solyom, S Takebayashi, S Yamaguchi, S-H Lee, SA Smallwood, SA Trelogan, SB Rothbart, SFC Soper, SK Mahadevaiah, SL Martin, SL Martin, SL Martin, SL Mathias, SP Sripathy, SS Tanaka, ST Grivna, T Matsui, T Singer, T Tanaka, T Watanabe, T Watanabe, T Watanabe, T-P Gu, TS Macfarlan, UM Galli, V Chapman, VV Vagin, W Deng, W Filipowicz, W Seifarth, W Wei, W Yan, WA Pastor, X Cai, X Nan, Y Kato, Y Seki, Y Tao, Y Unhavaithaya, Y Yabuta, Y Yotsuyanagi, Y-Q Su, Z Li, ZD Smith, ZD Smith   +241 more
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Dynamics of rye chromosome 1R regions with high or low crossover frequency in homology search and synapsis development. [PDF]

PLoS ONE, 2012
In many organisms, homologous pairing and synapsis depend on the meiotic recombination machinery that repairs double-strand DNA breaks (DSBs) produced at the onset of meiosis.
Nohelia T Valenzuela, Esther Perera, Tomás Naranjo   +2 more
doaj   +1 more source

Pushing the (nuclear) envelope into meiosis. [PDF]

, 2013
A recent study shows that a short isoform of a mammalian nuclear lamin is important for homologous chromosome interactions during meiotic prophase in ...
Dernburg, Abby F
core   +1 more source

Phospho-Regulation of Meiotic Prophase

Frontiers in Cell and Developmental Biology, 2021
Germ cells undergoing meiosis rely on an intricate network of surveillance mechanisms that govern the production of euploid gametes for successful sexual reproduction.
Funda M. Kar, Andreas Hochwagen
doaj   +1 more source

Conformational dynamics of the Hop1 HORMA domain reveal a common mechanism with the spindle checkpoint protein Mad2. [PDF]

, 2017
The HORMA domain is a highly conserved protein-protein interaction module found in eukaryotic signaling proteins including the spindle assembly checkpoint protein Mad2 and the meiotic HORMAD proteins.
Corbett, Kevin D, Komives, Elizabeth A, West, Alan MV   +2 more
core   +2 more sources

Ribonucleolytic resection is required for repair of strand displaced nonhomologous end-joining intermediates [PDF]

, 2013
Nonhomologous end-joining (NHEJ) pathways repair DNA double-strand breaks (DSBs) in eukaryotes and many prokaryotes, although it is not reported to operate in the third domain of life, archaea. Here, we describe a complete NHEJ complex, consisting of DNA
Bartlett, Edward, Brissett, Nigel C, Doherty, Aidan J   +2 more
core   +1 more source