A novel dual histone mark reader ZCWPW2 regulates meiotic recombination through lactylation and transcriptional regulation in humans and mice. [PDF]
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Spermatogenesis Beyond DNA: Integrated RNA Control of the Epitranscriptome and Three-Dimensional Genome Architecture. [PDF]
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Manipulating Engram Histone Acetylation Alters Memory Consolidation. [PDF]
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Chromosome rotation and formation of synapsis
Nature, 1976ALTHOUGH the rotation and oscillation of the nuclei of cultured spermatocytes have been known for some years1,2, no correlations of this phenomenon with the stages of mitosis or meiosis, or with the biochemical or cytogenetic events during germ-cell development have been made.
M, Parvinen, K O, Söderström
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Chromosome synapsis in hexaploids
Journal of Theoretical Biology, 1980Abstract Theoretical relationships between pachytene multivalent and bivalent frequencies in hexaploids are deduced from a model, based on chromosomes showing sequential association at equidistant pairing sites and uniform propensities for partner exchange throughout their lengths.
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The XY chromosome pair in mammalian males is sequestered into a transcriptionally dormant chromatin domain before the first meiotic division. New work shows that all chromosomes can suffer the same fate if they don't pair during meiosis, and that this may be part of a surveillance mechanism to protect against aneuploid gametes.
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