Results 311 to 320 of about 26,216 (365)

NAE1-mediated neddylation coordinates ubiquitination regulation of meiotic recombination during spermatogenesis. [PDF]

Theranostics
Xi Y, Gong C, Zhang Z, Zhu F, Zhang Y, Tang Y, Yan L, Jiang H, Qiao J, Liu Q.   +9 more
europepmc   +1 more source

Establishment of a humanized SCA2 mouse model carrying a CAA disruption preventing CAG repeat expansion in pathogenic genes

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a mouse model in which CAG repeats do not undergo microsatellite instability (MSI) across generations. A humanized ATXN2 cDNA with four CAA interruptions within 73 CAG expansions was inserted into the Rosa26 locus of C57BL/6J mice. At the same time, a 23 CAG control mouse model was also generated.
Yao Zhang, Yufei Li, Lin Zhang, Zhaoqing Li, Keqin Lin, Kai Huang, Zhaoqing Yang, Shaohui Ma, Hao Sun, Xiaochao Zhang   +9 more
wiley   +1 more source

Apomixis at high resolution: unravelling diplospory in Asteraceae. [PDF]

J Exp Bot
Cornaro L, Banfi C, Cavalleri A, van Dijk PJ, Radoeva T, Cucinotta M, Colombo L.   +6 more
europepmc   +1 more source

The Scale of Neurodegeneration in Moderate‐to‐Severe Traumatic Brain Injury: A Systematic Review of Longitudinal Studies

Annals of Neurology, EarlyView.
Synthesis of Literature: Neurodegeneration in Moderate‐Severe TBI. Objective Although moderate‐to‐severe traumatic brain injury (msTBI) was once considered a static neural event following resolution of acute injuries, numerous studies now demonstrate progressive losses to volume and white matter integrity in the months and years postinjury, leading to ...
Bhanu Sharma, Leanne Monteiro, Alana Changoor, Brenda Colella, Robin Green   +4 more
wiley   +1 more source

Aberrant activation of chromosome asynapsis checkpoint triggers oocyte elimination. [PDF]

Nat Commun
Jiao X, Liang Z, Li J, Bai L, Xu J, Liu Y, Lu LY.   +6 more
europepmc   +1 more source

The Intricate Functional Networks of Pre-mRNA Alternative Splicing in Mammalian Spermatogenesis. [PDF]

Int J Mol Sci
Jiang N, Li Y, Yin L, Yuan S, Wang F.
europepmc   +1 more source

Structural role for DNA Ligase IV in promoting the fidelity of non-homologous end joining. [PDF]

Nat Commun
Stinson BM, Carney SM, Walter JC, Loparo JJ.   +3 more
europepmc   +1 more source

Quantitative Analysis of Fluorescent Sensor Arrays

Analysis &Sensing, EarlyView.
Fluorescent sensor arrays have great potential for the quantification of analytes in complex systems. Herein, statistical multivariate techniques and deep learning models to provide quantitative information from such arrays are reviewed. Fluorescent sensor arrays address the limitations of a single sensor by leveraging multiple sensing elements to ...
Karandeep Grover, Muhammad Tahir Waseem, Haobo Guo, Elizabeth J. New   +3 more
wiley   +1 more source

RNF212B E3 ligase is essential for crossover designation and maturation during male and female meiosis in the mouse. [PDF]

Proc Natl Acad Sci U S A
Condezo YB, Sainz-Urruela R, Gomez-H L, Salas-Lloret D, Felipe-Medina N, Bradley R, Wolff ID, Tanis S, Barbero JL, Sánchez-Martín M, de Rooij D, Hendriks IA, Nielsen ML, Gonzalez-Prieto R, Cohen PE, Pendas AM, Llano E.   +16 more
europepmc   +1 more source

Anatolian ground squirrel (Spermophilus xanthoprymnus) retina: Comparative expression of synaptophysin, NeuN, calbindin‐D28k, parvalbumin, glial fibrillary acidic protein, and Iba‐1 during pre‐hibernation and hibernation

The Anatomical Record, EarlyView.
Abstract Hibernation induces significant molecular and cellular adaptations in the retina to maintain function under reduced metabolic conditions. This study aimed to investigate the expression of neuronal, synaptic, and glial markers in the retina of Spermophilus xanthoprymnus during pre‐hibernation and hibernation periods using immunohistochemical ...
Mehmet Özbek, Feyzullah Beyaz, Mustafa Öztop, Harun Karaca, Ahmet Cabir, Begüm Fatma Kiryar   +5 more
wiley   +1 more source