Results 221 to 230 of about 125,336 (300)

Harnessing synaptic vesicle release and recycling with antibody shuttle for targeted delivery of therapeutics to neurons. [PDF]

Mol Ther Methods Clin Dev
Yee KKL, Kumamoto J, Inomata D, Suzuki N, Harada R, Yumoto N.   +5 more
europepmc   +1 more source

Enhancing Neural Stem Cell Proliferation Using Polyurethane/CNT Scaffolds Functionalized With Liposomal Hesperidin for Neural Tissue Engineering

Nano Select, EarlyView.
A multifunctional electrospun scaffold combining polyurethane, carbon nanotubes, and liposomal hesperidin supports neural stem cell survival, adhesion, and expansion. This platform enhances conductivity, mechanical strength, and hydrophilicity while mimicking the native neural environment.
Arman Abroumand Gholami, Amir Mahdi Molavi, Meshkat Omrannezhad, Tahere Mokhtari, Shokoufeh Rahmani, Payam Moharreri, Fatemeh Gheybi, Fatemeh Tahmasebi, Hamideh Babaloo   +8 more
wiley   +1 more source

α-Synuclein-Assembled Synaptic Vesicle Pools at the Presynaptic Terminal: A Study of α-Synuclein Function Using a Novel Mouse Model. [PDF]

Acta Histochem Cytochem
Suzuki C, Yamaguchi J, Tanida I, Uchiyama Y.   +3 more
europepmc   +1 more source

What Role Does the Central Nervous System Play in Refractory LUTS, and What Are the Therapeutic Implications? ICI‐RS 2025

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk, Michel Wyndaele, Ana Charrua, Christopher Fry, Paul Abrams, Gommert A. van Koeveringe, Anthony J. Kanai, Marcus J. Drake   +7 more
wiley   +1 more source

Cerebrospinal fluid and brain positron emission tomography measures of synaptic vesicle glycoprotein 2A: Biomarkers of synaptic density in Alzheimer's disease. [PDF]

Alzheimers Dement
Mecca AP, Ashton NJ, Chen MK, O'Dell RS, Toyonaga T, Zhao W, Young JJ, Salardini E, Bates KA, Ra J, Goodcase S, Silva-Rudberg JA, Nabulsi NB, Brinkmalm A, Kvartsberg H, Schöll M, Nilsson J, Arnsten AFT, Huang Y, Hansson O, Zetterberg H, Carson RE, Blennow K, van Dyck CH.   +23 more
europepmc   +1 more source

CUL3‐Related Neurodevelopmental Disorder: Expanding the Prenatal Phenotype

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Pathogenic variants of the CUL3 gene are known to cause a neurodevelopmental disorder with a partially described prenatal phenotype. This study further characterizes and expands the spectrum of prenatal sonographic findings associated with the disorder to improve prenatal diagnosis and counseling.
Yoel Gofin, Tania Dery, Tamar Tenne, Racheli Goldfarb Yaacobi, Emilie Block, Marina Lifshitc Kalis, Hagar Mor‐Shaked, Liza Douiev‐Charpak, Rivka Birnbaum, Mordechai Shohat, Ofer Markovich, Debora Kidron, Rivka Sukenik‐Halevy   +12 more
wiley   +1 more source

CryoVesNet: A dedicated framework for synaptic vesicle segmentation in cryo-electron tomograms. [PDF]

J Cell Biol
Khosrozadeh A, Seeger R, Witz G, Radecke J, Sørensen JB, Zuber B.   +5 more
europepmc   +1 more source

Reduction in Synaptic Vesicle Protein Abundance but Increased Amounts of Nsg2 and Lpcat1 in Cerebral Cortices Without the Endosomal SNARE Proteins Vti1a and Vti1b

PROTEOMICS, EarlyView.
ABSTRACT Absence of the endosomal SNAREs vti1a and vti1b results in perinatal death and severe neuronal phenotypes in mice, while lack of one of these proteins results in minor phenotypes. Proteomic differences were investigated to obtain a deeper insight into processes in which vti1a and vti1b are involved.
Julia Gottschalk, Katharina Kotschnew, Julia Hahn, Thomas Patschkowski, Gabriele von Fischer von Mollard   +4 more
wiley   +1 more source

Persistence of quantal synaptic vesicle recycling in virtual absence of dynamins. [PDF]

J Physiol
Afuwape OAT, Chanaday NL, Kasap M, Monteggia LM, Kavalali ET.   +4 more
europepmc   +1 more source

G Protein–Coupled Receptors in Olfactory Signaling and Related Disorders: Mechanisms and Therapeutic Implications

Sensory Neuroscience, EarlyView.
This schematic highlights GPCRs as the central hub of olfactory signaling in health and disease. The central GPCR shows odorant activation and downstream pathways. Surrounding quadrants illustrate four GPCR‐mediated themes: odor perception and adaptation, mucosal immunity and regeneration, memory consolidation via neural circuits, and GPCR‐related ...
Zishuo Guo, Hongjie Du, Fanyu Yuan, Yuhan Dong, Fangyuan Zhu, Jian Liu, Chengzhilin Li, Xu Guo, Zhaoze Yang, Wenwen Qi, Ming Xia, Chengcheng Liu   +11 more
wiley   +1 more source