Results 241 to 250 of about 531,557 (374)

Drebrin Upregulation Regulates Astrocyte Polarization and Supports Tissue Recovery After Spinal Cord Injury in Mice

open access: yesGlia, EarlyView.
ABSTRACT Spinal cord injury (SCI) results in significant disruption of nerve fibers responsible for transmitting signals between the brain and body, often leading to partial or complete motor, sensory, and autonomic dysfunction below the injury site. Astrocytes are an important component in scar formation, crucial for suppression of injury propagation,
Barbora Smejkalová   +12 more
wiley   +1 more source

Flower/FLWR-1 regulates neuronal activity via the plasma membrane Ca<sup>2+</sup> ATPase to promote recycling of synaptic vesicles. [PDF]

open access: yesElife
Seidenthal M   +8 more
europepmc   +1 more source

The endophilin curvature-sensitive motif requires electrostatic guidance to recycle synaptic vesicles in vivo. [PDF]

open access: yesDev Cell, 2022
Zhang L   +8 more
europepmc   +1 more source

Diverse Subpopulations of Reactive Astrocytes Following Chronic Toxoplasma Infection

open access: yesGlia, EarlyView.
Toxoplasma infection results in distinct astrocyte subpopulations. Chronically labeled reactive astrocytes appear transcriptionally plastic and can regain acute inflammatory responding and naive homeostatic astrocytic gene patterns in the presence of ongoing neuroinflammation.
Zoe A. Figueroa   +7 more
wiley   +1 more source

SV2B defines a subpopulation of synaptic vesicles. [PDF]

open access: yesJ Mol Cell Biol
Paulussen I   +10 more
europepmc   +1 more source

Investigating the role of SARM1 in central nervous system

open access: yesIbrain, EarlyView.
Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang   +4 more
wiley   +1 more source

DMXL2 Is Required for Endocytosis and Recycling of Synaptic Vesicles in Auditory Hair Cells. [PDF]

open access: yesJ Neurosci
Peng H   +12 more
europepmc   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

open access: yesiMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu   +8 more
wiley   +1 more source

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