The separation of synaptic vesicles from nerve-ending particles ('synaptosomes').
V. P. Whittaker +3 more
semanticscholar +1 more source
Depressive symptoms as independent correlates of epilepsy‐related cognitive burden
Abstract Objective This study was undertaken to assess the relationship between the severity of depression and anxiety symptoms and epilepsy‐related variables and cognitive burden in people with epilepsy (PwE), as assessed using EpiTrack. Methods We prospectively enrolled a cohort of PwE who underwent EpiTrack and evaluation by Generalized Anxiety ...
Biagio Maria Sancetta +10 more
wiley +1 more source
Intersectin-1 enhances calcium-dependent replenishment of the readily releasable pool of synaptic vesicles during development. [PDF]
Yang YM +13 more
europepmc +1 more source
Abstract Objective This study was undertaken to evaluate whether synaptic vesicle protein 2A (SV2A) expression on peripheral immune cells predicts treatment response to levetiracetam in epilepsy. Methods High‐dimensional flow cytometry was used to prospectively assess SV2A expression on immune cells from levetiracetam responders, nonresponders, and ...
Johannes Lang +4 more
wiley +1 more source
Overlapping role of synaptophysin and synaptogyrin family proteins in determining the small size of synaptic vesicles. [PDF]
Park D +6 more
europepmc +1 more source
New insights into epileptic spasm generation and treatment from the TTX animal model
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann +2 more
wiley +1 more source
5-Hydroxytryptophan artificial synaptic vesicles across the blood-brain barrier for the rapid-acting treatment of depressive disorder. [PDF]
Chang P +8 more
europepmc +1 more source
A 38,000-dalton membrane protein (p38) present in synaptic vesicles.
R. Jahn +3 more
semanticscholar +1 more source
Status epilepticus: Updates on mechanisms and treatments
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley +1 more source

