Disruption of Dopamine Homeostasis Associated with Alteration of Proteins in Synaptic Vesicles: A Putative Central Mechanism of Parkinson's Disease Pathogenesis. [PDF]
Jin X, Si X, Lei X, Liu H, Shao A, Li L.
europepmc +1 more source
Synaptic Vesicle Recycling in Cultured Cerebellar Granule Cells: Role of Vesicular Acidification and Refilling [PDF]
Michael A. Cousin, David G. Nicholls
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ABSTRACT Neuroimaging with positron emission tomography (PET) has been instrumental in elucidating neurobiological mechanisms behind therapeutical trials in Parkinson's disease (PD). A variety of medical and neurosurgical interventions have been evaluated using many radioligands that reveal molecular basis for target engagement and brain responses in ...
Vijay Dhawan+4 more
wiley +1 more source
Synaptotagmin 7 docks synaptic vesicles to support facilitation and Doc2α-triggered asynchronous release. [PDF]
Wu Z+7 more
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BACE1 controls synaptic function through modulating release of synaptic vesicles. [PDF]
Das B+6 more
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A morphometric analysis of isolated Torpedo electric organ synaptic vesicles following stimulation. [PDF]
Dowe, G., Fox, G., Koetting, D.
core
Secretory vesicle and cell surface markers for human endocrine pancreatic and pituiary tumors [PDF]
Gratzl, Manfred+4 more
core +1 more source
Endocytosis of VAMP is facilitated by a synaptic vesicle targeting signal. [PDF]
Eric Grote, R B Kelly
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Abstract Traditionally, clinical trials of putative disease‐modifying therapies in Parkinson's disease have enrolled untreated patients at the earliest clinical stages of their disease. Due to a number of challenges inherent with this approach, there has been a recent move to a different study design, enrolling patients who are already taking “stable ...
M. Maral Mouradian+2 more
wiley +1 more source
Physical presence of chemical synapses is necessary for turning behavior of anterograde synaptic vesicles at the branch point of PLM neurons in C. elegans. [PDF]
Vasudevan A, Koushika SP.
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