Results 81 to 90 of about 12,224 (202)
TRIP13PCH-2 promotes Mad2 localization to unattached kinetochores in the spindle checkpoint response. [PDF]
, 2015 The spindle checkpoint acts during cell division to prevent aneuploidy, a hallmark of cancer. During checkpoint activation, Mad1 recruits Mad2 to kinetochores to generate a signal that delays anaphase onset.
Bhalla, Needhi +3 more
core +1 more source
Evolutionary history of the mammalian synaptonemal complex [PDF]
Chromosoma, 2016 The synaptonemal complex (SC), a key structure of meiosis that assembles during prophase I, has been initially described 60 years ago. Since then, the structure has been described in many sexually reproducing organisms. However, the SC protein components were characterized in only few model organisms.
Johanna, Fraune +5 more
openaire +2 more sources
Meiotic nuclear divisions in budding yeast require PP2ACdc55-mediated antagonism of Net1 phosphorylation by Cdk [PDF]
, 2011 During meiosis, one round of deoxyribonucleic acid replication is followed by two rounds of nuclear division. In Saccharomyces cerevisiae, activation of the Cdc14 early anaphase release (FEAR) network is required for exit from meiosis I but does not lead
Arumugam, Prakash +5 more
core +3 more sources
YKT6 Is Essential for Male Fertility by Promoting Meiosis Progression During Spermatogenesis of Mice
Cell Proliferation, Volume 59, Issue 1, January 2026.Specifically ablating Ykt6 in pre‐meiotic germ cells and meiotic spermatocytes leads to complete sterility and meiotic arrest in conditional knockout male mice. YTK6 is required for stabilising intercellular bridges between spermatocytes due to its key role in maintaining protein homeostasis and vesicular transport‐dependent functions in spermatocytes,
Jie Cen +8 more
wiley +1 more source
Journal of Fish Biology, Volume 108, Issue 1, Page 92-102, January 2026.Abstract Blue‐eyed red‐fin pleco Hypostomus soniae (family Loricariidae) presented a putative sex system XX/XY in early stage. Aiming to explore the inter‐populational karyotypic variation and proposed emergence of the XX/XY system, we studied 13 H. soniae individuals (6 males, 7 females) from the Tapajós River.
Luan Aércio Melo Maciel +6 more
wiley +1 more source
New method for visualization of C-heterochromatin in synaptonemal complex spreads
Comparative Cytogenetics, 2013 DAPI staining of the metaphase chromosomes pretreated with barium hydroxide generates a C-like banding pattern. In this work a protocol for visualizing similar pattern at the synaptonemal complex (SC) spreads after immunostaining is suggested.
Artem Lisachov
doaj +1 more source
The Role of Foundational Relations in the Alignment of Biomedical Ontologies [PDF]
, 2004 The Foundational Model of Anatomy (FMA) symbolically represents the structural organization of the human body from the macromolecular to the macroscopic levels, with the goal of providing a robust and consistent scheme for classifying anatomical entities
Rosse, Cornelius, Smith, Barry
core +1 more source
Diploid origins and early genome stabilization in the allotetraploid Arabidopsis suecica
New Phytologist, Volume 249, Issue 1, Page 524-538, January 2026.Summary Polyploidization, followed by genome downsizing, is a recurrent evolutionary cycle that dramatically reshapes genome structure. Newly formed polyploids must quickly adjust their cell division machinery to maintain stable chromosome inheritance, while long‐term stabilization involves rediploidization, returning the genome to a diploid‐like state.
Robin Burns +6 more
wiley +1 more source
Sequential Loading of Cohesin Subunits during the First Meiotic Prophase of Grasshoppers [PDF]
, 2007 A previous version of this article appeared as an Early Online Release on January 2, 2007 (doi:10.1371/journal.pgen.0030028.eor).The cohesin complexes play a key role in chromosome segregation during both mitosis and meiosis.
Valdeolmillos, Ana M. +10 more
core +1 more source
Eukaryogenesis From FECA to LECA: Radical Steps Along the Way
BioEssays, Volume 47, Issue 11, November 2025.How did the last eukaryotic common ancestor (LECA) population evolve? Recent evidence shows an Asgard archaeon‐like organism acquiring a bacterium, the future mitochondrion, going from symbiosis to endosymbiosis. I postulate that almost all salient LECA characteristics could have resulted from the ensuing enhanced ATP generation and internal reactive ...
Dave Speijer
wiley +1 more source