Results 81 to 90 of about 6,353,452 (269)

YKT6 Is Essential for Male Fertility by Promoting Meiosis Progression During Spermatogenesis of Mice

Cell Proliferation, EarlyView.
Specifically ablating Ykt6 in pre‐meiotic germ cells and meiotic spermatocytes leads to complete sterility and meiotic arrest in conditional knockout male mice. YTK6 is required for stabilising intercellular bridges between spermatocytes due to its key role in maintaining protein homeostasis and vesicular transport‐dependent functions in spermatocytes,
Jie Cen, Xiaochen Yu, Ziqi Wang, Wenbo Liu, Jianze Xu, Qian Fang, Fei Gao, Yongzhi Cao, Hongbin Liu   +8 more
wiley   +1 more source

Sycp1 Is Not Required for Subtelomeric DNA Double-Strand Breaks but Is Required for Homologous Alignment in Zebrafish Spermatocytes

Frontiers in Cell and Developmental Biology, 2021
In meiotic prophase I, homologous chromosomes are bound together by the synaptonemal complex, in which two axial elements are connected by transverse filaments and central element proteins.
Yukiko Imai, Kenji Saito, Kazumasa Takemoto, Fabien Velilla, Toshihiro Kawasaki, Toshihiro Kawasaki, Kei-ichiro Ishiguro, Noriyoshi Sakai, Noriyoshi Sakai   +8 more
doaj   +1 more source

Surface-spreading technique of meiotic cells and immunodetection of synaptonemal complex proteins in teleostean fishes [PDF]

, 2015
Background: Different moderrn methodologies are presently available to analyze meiotic chromosomes. These methods permit investigation of the behavior of chromosomes in the normal complement and of sex and B chromosomes, two special types of chromosomes ...
Cláudio Oliveira, Cristian Araya-Jaime, Duílio de Andrade Silva, Fausto Foresti, Masakane Yamashita, Toshiharu Iwai, Érica Serrano   +6 more
core   +2 more sources

RECQ4 restricts non‐interfering crossover formation to fine‐tune meiotic recombination rates in rice

Plant Biotechnology Journal, EarlyView.
Summary Crop breeding fundamentally depends on meiotic crossovers (COs) to reshuffle genetic material and integrate favourable alleles into elite cultivars. Recombination frequency is of paramount importance in this process. Higher recombination rates enhance the probability of breaking linkage drag and generating novel allelic combinations.
Yafei Li, Hanli You, Xinjie Cheng, Bingxin Wang, Yangzi Zhao, Jiawei Chen, Lei Cao, Minsi Wen, Yansong Zhang, Zhuoran Chen, Qiong Luo, Zhukuan Cheng   +11 more
wiley   +1 more source

Pairing of homologous chromosomes in C. elegans meiosis requires DEB-1 - an orthologue of mammalian vinculin

Nucleus, 2019
During meiosis, homologous chromosomes undergo a dramatic movement in order to correctly align. This is a critical meiotic event but the molecular properties of this ‘chromosomal dance’ still remainunclear.
Jana Rohožková, Lenka Hůlková, Jana Fukalová, Petr Flachs, Pavel Hozák   +4 more
doaj   +1 more source

Strong Signatures of Selection on Candidate Genes Underlying Core Speciation Mechanisms in Desert Tortoises

Molecular Ecology Resources, Volume 25, Issue 6, August 2025.
ABSTRACT Genomic incompatibilities and differential ecological adaptation are thought to be fundamental mechanisms of speciation. In this study, we generated a chromosome‐scale reference genome and annotation for Gopherus morafkai , the Sonoran Desert tortoise, and conducted a detailed analysis of genes under positive selection with its sister species,
Sarah M. Baty, Raúl Araya‐Donoso, Avery Paulsen, Avery Williams, Dale F. DeNardo, Kenro Kusumi, Greer A. Dolby   +6 more
wiley   +1 more source

Nicotinamide Riboside Supplementation Alleviates Testicular Aging Induced by Disruption of Qprt‐Dependent NAD+ De Novo Synthesis in Mice

Aging Cell, Volume 24, Issue 6, June 2025.
In Qprt‐deficient mice, testicular NAD+ levels decline accelerated with age, leading to mitochondrial dysfunction, disrupted DSB repair, impaired meiotic sex chromosome inactivation, and germ cell loss. Nicotinamide riboside (NR) supplementation restores NAD+ levels and alleviates these defects, highlighting the importance of NAD+ de novo synthesis in ...
Yining Xu, Huan Wang, Hui Li, Chenlu Wei, Zhenye Zhu, Yanqing Zhao, Jiajia Zhu, Min Lei, Yingpu Sun, Qingling Yang   +9 more
wiley   +1 more source

Chromosome condensation in mitosis and meiosis of rye (Secale cereale L.) [PDF]

, 2004
Structural investigation and morphometry of meiotic chromosomes by scanning electron microscopy (in comparison to light microscopy) of all stages of condensation of meiosis I + II show remarkable differences during chromosome condensation in mitosis and ...
Herrmann, Reinhold G., Wanner, Gerhard, Zoller, J. F.   +2 more
core   +1 more source

Molecular characterization and expression analysis of SYCP1 and SYCP3 in hybrid fish derived from Megalobrama amblycephala × Culter alburnus

Journal of the World Aquaculture Society, Volume 56, Issue 3, June 2025.
Abstract SYCP1 and SYCP3 are essential testis‐specific genes for centromere pairing during meiosis, as well as for spermatogenesis and fertility in male germ cells. However, it is still unclear regarding the expression patterns in the fertile reciprocal hybrid offspring of Megalobrama amblycephala (blunt snout bream, BSB, 2n = 48) × Culter alburnus ...
Jia Xu, Yuandong Sun, Chang Wu, Xiaojuan Cui, Yujing Li, Zhongwei Hua, Yifei Zhang   +6 more
wiley   +1 more source

Crystal structure of Hop2-Mnd1 and mechanistic insights into its role in meiotic recombination [PDF]

, 2015
In meiotic DNA recombination, the Hop2-Mnd1 complex promotes Dmc1-mediated single-stranded DNA (ssDNA) invasion into homologous chromosomes to form a synaptic complex by a yet-unclear mechanism.
Alexandra-Styliani Kalantzi, Bergerat, Bishop, Brown, Brunger, Bugreev, Byung-Ha Oh, Case, Chan, Chen, Chi, Cho, Christopher P. Toseland, Cloud, de Massy, De Vlaminck, de Vries, Emsley, Enomoto, Ferrari, Garcia, Haruta, Hayase, Ho-Chul Shin, Holm, Hyun-Ah Kang, Hyun-Min Kim, Keeney, Keeney, Kokabu, Kuwabara, Lange, Leu, Lu, Lu, Lu, Matteo Dal Peraro, Moktan, Morrison, Neale, Okorokov, Otwinowski, Pettersen, Petukhova, Petukhova, Pezza, Pezza, Phillips, Ploquin, Qiao, Rabitsch, Roeder, Rothenberg, Say, Schwacha, Sheridan, Sheridan, Soding, Stephan Gruber, Terwilliger, Tsai, Tsubouchi, Tsubouchi, Uanschou, van der Heijden, Wright, Zhao   +66 more
core   +3 more sources