Results 161 to 170 of about 47,565 (201)
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Localization of Synaptophysin Immunoreactivity in the Human Liver
Scandinavian Journal of Gastroenterology, 1994The distribution of synaptophysin, specifically located in nerve terminals, was investigated immunohistochemically in normal and diseased human livers in 4 patients with normal liver, 6 with chronic active hepatitis, 12 with cirrhosis, and 8 with hepatocellular carcinoma. In normal liver and chronic hepatitis synaptophysin immunoreactivity was detected
N, Kanda +5 more
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1994
Abstract cDNAs encoding synaptophysin have been sequenced from several mammalian species (GenBank accession number for rat cDNA: X06177) and from Torpedo1·5They encode a protein of approximately 34,000 Daltons with four predicted transmembrane segments and the C- and N-termini facing the cytoplasm124·5.
R Jahn, T C Südhof
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Abstract cDNAs encoding synaptophysin have been sequenced from several mammalian species (GenBank accession number for rat cDNA: X06177) and from Torpedo1·5They encode a protein of approximately 34,000 Daltons with four predicted transmembrane segments and the C- and N-termini facing the cytoplasm124·5.
R Jahn, T C Südhof
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Synaptophysin expression in the striatum in Huntington's disease
Acta Neuropathologica, 1990This immunohistochemical study compares the expression of synaptophysin (SYP) in the striatum in Huntington's disease (HD) with that of calcineurin (CaN), a marker for striatal medium-sized spinous neurons. As compared to controls, in the HD striatum there was a significant loss of SYP immunoreactivity with residual staining displaying an inhomogeneous
S, Goto, A, Hirano
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Synaptophysin: an Immunohistochemical Marker for Animal Dysautonomias
Journal of Comparative Pathology, 2005Equine and feline dysautonomias are characterized histopathologically by degenerating neurons with chromatolysis, pyknotic and sometimes eccentric nuclei, and loss of Nissl substance in the peripheral autonomic ganglia. Because it may be difficult to distinguish pathological from post-mortem changes in affected ganglia by histopathological examination,
M, Hilbe +3 more
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Calcium‐dependent serine phosphorylation of synaptophysin
Synapse, 1993AbstractThe phosphorylation of synaptophysin, a major integral membrane protein of small synaptic vesicles, was found to be regulated in a Ca2+ ‐dependent manner in rat cerebrocortical slices, synaptosome preparations, and highly purified synaptic vesicles isolated from rat forebrain. K+‐induced depolarization of slices and synaptosomes prelabeled with
J L, Rubenstein +2 more
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SYNAPTOPHYSIN STAINING IN NORMAL BRAIN
Journal of Neuropathology and Experimental Neurology, 1997Neuronal and mixed glioneuronal tumors traditionally have comprised a very small percentage of intrinsic central nervous system neoplasms, although they are somewhat more common among juvenile brain tumors and in the temporal lobe. Neuronal differentiation increasingly is recognized in pleomorphic xanthoastrocytoma, intraventricular neurocytoma, and ...
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Striatal synaptophysin levels are not indicative of dopaminergic supersensitivity
Neuropharmacology, 1997Recent evidence suggests that behavioral supersensitivity to dopamine (DA) agonists observed in chronic neuroleptic-treated animals might be related to changes in synaptic morphology and density. The aim of this study was to test this hypothesis using Western blotting to determine the striatal synaptophysin levels in rats chronically treated with ...
C, Marin, E, Tolosa
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[A synaptic marker synaptophysin].
Morfologiia (Saint Petersburg, Russia), 2015The review summarizes the current data on synaptophysin (SYP), its functional role in the cell and the use of SYP immunocytochemistry for labeling the synaptic contacts. SYP is a transmembrane glycoprotein found in small presynaptic vesicles of the nerve cells and in microvesicles of the neuroendocrine cells.
Ye A, Kolos +2 more
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Synaptophysin in the Cochlear Nucleus Following Acoustic Trauma
Experimental Neurology, 2002Chinchillas are notable for a low-frequency hearing range similar to that of humans and a marked sensitivity to loud noise. A single noise exposure that produces cochlear damage may lead to progressive loss of synaptic endings in the cochlear nucleus, followed by new axonal growth.
S M, Muly +3 more
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Sharing of antigenic epitopes between synaptophysin and granulophysin
Journal of Cellular Biochemistry, 1992AbstractThe immunological crossreactivity between the two granule‐specific membrane glycoproteins, synaptophysin and granulophysin, was studied using a series of site‐specific monoclonal and polyclonal antibodies. The epitope relatedness of six monoclonal antibodies against granulophysin was examined by competitive ELISA.
A, Shalev +4 more
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