, 1995 Previous studies have suggested the importance of synaptophysin (p38), a major integral membrane protein of the synaptic vesicle, in transmitter secretion, but few have directly addressed its functional role at intact synapses.
MM Poo +4 more
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Loss of Synaptophysin Immunoexpression in Primary Progressive Aphasia
American Journal of Alzheimer's Disease & Other Dementias®, 2012 Primary progressive aphasia (PPA) is characterized by progressive loss of language, unassociated with generalized cognitive loss and with no uniform pathological abnormality. To address whether the issue of PPA is associated with synaptic loss, we compared immunoreactivity in Broca’s area with that in the adjacent gyrus from a case
Carol F, Lippa, Andrea L, Rosso
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Synaptophysin Regulates the Kinetics of Synaptic Vesicle Endocytosis in Central Neurons [PDF]
, 2011 SummaryDespite being the most abundant synaptic vesicle membrane protein, the function of synaptophysin remains enigmatic. For example, synaptic transmission was reported to be completely normal in synaptophysin knockout mice; however, direct experiments
Chapman, Edwin R. +3 more
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Youngest case of third ventricular anaplastic neurocytoma
Indian Journal of Medical and Paediatric Oncology, 2010 A 6-year-old child presented to us with on and off headache and vomiting for 4 months. On examination, there was bilateral papilledema with mild intracranial hypertension but with no neurological deficits.
Chinnikatti Shravan +4 more
doaj
The Ca2+ sensor protein Swiprosin-1/EFhd2 is present in neurites and involved in kinesin-mediated transport in neurons [PDF]
, 2014 This work was supported by grants from the German Science Foundation (Deutsche Forschungsgemeinschaft, DFG; FOR832, to DM), the German Federal Ministry of Education and Research (01GQ113; to BW), the Bavarian Ministry of Sciences, Research and the Arts ...
Oliver Welzel +49 more
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Neocortical synaptophysin asymmetry and behavioral lateralization in chimpanzees (Pan troglodytes)
, 2010 Although behavioral lateralization is known to correlate with certain aspects of brain asymmetry in primates, there are limited data concerning hemispheric biases in the microstructure of the neocortex. In the present study, we investigated whether there
Schapiro, Steve +10 more
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Neuroendocrine gene subsets are uniquely dysregulated in prostate adenocarcinoma
Cancer Biology & TherapyProstate cancer has heterogeneous growth patterns, and its prognosis is the poorest when it progresses to a neuroendocrine phenotype. Using bioinformatic analysis, we evaluated RNA expression of neuroendocrine genes in a panel of five different cancer ...
Nicole M. Naranjo +14 more
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Torpedo synaptophysin: evolution of a synaptic vesicle protein
Brain Research, 1990 Synaptophysin is an integral membrane protein of synaptic vesicles found in neurons and endocrine cells. Synaptophysin monomers associate into hexamers forming a large conductance channel. We present an analysis of synaptophysin from the nervous system of the marine ray Torpedo californica.
D, Cowan, M, Linial, R H, Scheller
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Einfluß der synaptischen Vesikelproteine Synaptophysin und Synaptobrevin auf Wachstum und Differenzierung der hippocampalen Zellkultur [PDF]
, 1999 Ziel der vorliegenden Arbeit war es, die Rolle der synaptischen Vesikelproteine Synaptophysin und Synaptobrevin bei Wachstum und Differenzierung der primär dissoziierten hippocampalen Zellkultur 17 Tage alter Mäuseembryonen zu untersuchen.
Gorsleben, Martin
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Primary breast neuroendocrine carcinoma: a case report and literature review
Zhongguo linchuang yanjiuObjective To report a case of primary neuroendocrine breast cancer (NEBC)，and to provide clinical reference for the diagnosis and treatment of the disease.
CHEN Jiaying +3 more
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