Results 61 to 70 of about 589,327 (270)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Self-organized and driven phase synchronization in coupled maps [PDF]

open access: yes, 2003
We study the phase synchronization and cluster formation in coupled maps on different networks. We identify two different mechanisms of cluster formation; (a) {\it Self-organized} phase synchronization which leads to clusters with dominant intra-cluster ...
A. Pikovsky   +8 more
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

New type of chaos synchronization in discrete-time systems: the F-M synchronization

open access: yesOpen Physics, 2018
In this paper, a new type of synchronization for chaotic (hyperchaotic) maps with different dimensions is proposed. The novel scheme is called F – M synchronization, since it combines the inverse generalized synchronization (based on a functional ...
Ouannas Adel   +5 more
doaj   +1 more source

Two Scenarios of Breaking Chaotic Phase Synchronization

open access: yes, 2007
Two types of phase synchronization (accordingly, two scenarios of breaking phase synchronization) between coupled stochastic oscillators are shown to exist depending on the discrepancy between the control parameters of interacting oscillators, as in the ...
A. A. Koronovskii   +29 more
core   +1 more source

Synchronization Implies Seizure or Seizure Implies Synchronization? [PDF]

open access: yesBrain Topography, 2013
22 pages, 6 figures and 5 ...
Majumdar, Kaushik   +2 more
openaire   +3 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Research on Time and Phase Synchronization for Distributed Aperture Coherent Radar

open access: yesLeida xuebao, 2013
As a new radar technology, the distributed aperture coherent radar would be the next generation radar, which is more easily to transport and less expensive than the traditional large aperture radar.
Zeng Tao   +3 more
doaj   +1 more source

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