Results 111 to 120 of about 23,952,755 (264)

Association of Syndecan-1 immunoexpression with epithelial dysplasia in oral verrucous carcinoma

Bangabandhu Sheikh Mujib Medical University Journal
Background: Oral verrucous carcinoma (OVC) is an uncommon variant of well-differentiated squamous cell carcinoma with an excellent prognosis. Epithelial dysplasia in OVC is a sign of a poorer prognosis.
Md. Akhtaruzzaman, Bishnu Pada Dey, Israt Jahan, Md. Mahabub Alam, Sultana Gulshana Banu   +4 more
doaj   +1 more source

Immunohistochemical expression of heparanase isoforms and syndecan-1 proteins in colorectal adenomas

European Journal of Histochemistry, 2016
The proteoglycan syndecan-1 and the endoglucuronidases heparanase-1 and heparanase-2 are involved in molecular pathways that deregulate cell adhesion during carcinogenesis.
J. Waisberg, T.R. Theodoro, L.L. Matos, F.B. Orlandi, R.L. Serrano, G.T. Saba, M.A.S. Pinhal   +6 more
doaj   +1 more source

Circulating syndecan-1 is reduced in pregnancies with poor fetal growth and its secretion regulated by matrix metalloproteinases and the mitochondria

Scientific Reports, 2021
Fetal growth restriction is a leading cause of stillbirth that often remains undetected during pregnancy. Identifying novel biomarkers may improve detection of pregnancies at risk.
Damanpreet Garcha, Susan P. Walker, Teresa M. MacDonald, Jon Hyett, Jessica Jellins, Jenny Myers, Sebastian E. Illanes, Jhy K. Nien, Manuel Schepeler, Emerson Keenan, Carole-Anne Whigham, Ping Cannon, Elizabeth Murray, Tuong-Vi Nguyen, Manju Kandel, Joshua Masci, Ciara Murphy, Tess Cruickshank, Natasha Pritchard, Natalie J. Hannan, Fiona Brownfoot, Alexandra Roddy Mitchell, Anna Middleton, Gabrielle Pell, Georgia P. Wong, Stephen Tong, Tu’uhevaha J. Kaitu’u-Lino   +26 more
doaj   +1 more source

Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles.

JCI Insight, 2019
Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal lung disease. A maladaptive epithelium due to chronic injury is a prominent feature and contributor to pathogenic cellular communication in IPF.
T. Parimon, C. Yao, D. Habiel, Lingyin Ge, S. Bora, Rena Brauer, C. Evans, T. Xie, Felix Alonso-Valenteen, L. Medina-Kauwe, D. Jiang, P. Noble, C. Hogaboam, N. Deng, O. Burgy, T. Antes, M. Königshoff, B. Stripp, S. Gharib, Peter Chen   +19 more
semanticscholar   +1 more source

An acute rise of plasma sodium concentration associates with syndecan-1 shedding during hemodialysis.

AJP - Renal Physiology, 2020
Endothelial dysfunction (ED) contributes to the high incidence of cardiovascular events in hemodialysis patients. Syndecan-1 in the endothelial glycocalyx can be shed into the circulation serving as a biomarker for ED.
J. Koch, Nienke M A Idzerda, Esmée M. Ettema, H. Kuipers, Wendy A. Dam, J. van den Born, C. Franssen   +6 more
semanticscholar   +1 more source

FKBP5 Mediates Alveolar Fibroblast Necroptosis During Acute Respiratory Distress Syndrome

Cell Proliferation, EarlyView.
Structure diagram of alveolar fibroblast activation in septic ARDS model. FKBP5‐mediated alveolar fibroblast necroptosis, leading to the activation of NF‐κB signalling and the secretion of cytokines and the recruitment of neutrophils, and further orchestrating the inflammatory environment of the alveolar epithelia in septic ARDS.
Dong Zhang, Wei Liu, Ting Sun, Yangyang Xiao, Qiuwen Chen, Xiao Huang, Xiaozhi Wang, Qian Qi, Hao Wang, Tao Wang   +9 more
wiley   +1 more source

A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure [PDF]

, 2017
Aims: It is unclear whether distinct pathophysiological processes are present among patients with acute heart failure (AHF), with and without diabetes.
Bloomfield, Daniel M., Cleland, John G.F., Cotter, Gad, Davison, Beth A., Demissei, Biniyam G., Dittrich, Howard, Ezekowitz, Justin A., Givertz, Michael M., Hillege, Hans L., Khan, Mohsin A.F., Metra, Marco, O'Connor, Christopher M., Ponikowski, Piotr, Sharma, Abhinav, Teerlink, John R., Tromp, Jasper, van Veldhuisen, Dirk J., Voors, Adriaan A.   +17 more
core   +2 more sources

Principal mechanisms of extracellular matrix‐mediated cell–cell communication in physiological and tumor microenvironments

The FEBS Journal, EarlyView.
Intracellular communication controls the processing of generated signals so that every cell type can successfully respond. The extracellular matrix (ECM) is a fundamental regulator of cell communication and signaling through the strict orchestration and functions of its bioactive components.
Zoi Piperigkou, Sylvia Mangani, Nikolaos E. Koletsis, Christos Koutsakis, Nicholas S. Mastronikolis, Marco Franchi, Nikos K. Karamanos   +6 more
wiley   +1 more source

Corrigendum: Heparanase Promotes Syndecan-1 Expression to Mediate Fibrillar Collagen and Mammographic Density in Human Breast Tissue Cultured ex vivo [PDF]

, 2021
Xuan Huang, Gina Reye, Konstantin I. Momot, Tony Blick, Thomas Lloyd, Wayne D. Tilley, Theresa E. Hickey, Cameron Snell, Rachel K. Okolicsanyi, Larisa M. Haupt, Vito Ferro, Erik W. Thompson, Honor J. Hugo   +12 more
openalex   +1 more source

Regulation of vascular smooth muscle cell calcification by syndecan-4/FGF-2/PKCα signaling and cross-talk with TGFβ [PDF]

, 2017
Aims: Vascular calcification is a major cause of morbidity and mortality. Fibroblast growth factor-2 (FGF-2) plays an instructive role in osteogenesis and bone development, but its role in vascular calcification was unknown.
Alam, Ann E. Canfield, Baeyens, Biver, Catherine L.R. Merry, Chen, Chen, Collett, Debiais, Dombrowski, Fakhry, Galea, Gonzalez, Hagihara, Huang, Hyde, Ju, Kapustin, Krohn, Kuriyama, Latif, Lee, Lehto, Leopold, Lim, Ling, London, Marie, Mark R. Morgan, Montero, Morgan, Morgan, Naganawa, Nakahara, Nakayama, Nakura, Oh, Ornitz, Partovian, Rennenberg, Samantha J. Borland, Sheila E. Francis, Shona C. Borland, Teplyuk, Thomas G. Morris, Turner, Watson, Yan   +47 more
core   +3 more sources