Association of Syndecan-1 immunoexpression with epithelial dysplasia in oral verrucous carcinoma
Bangabandhu Sheikh Mujib Medical University JournalBackground: Oral verrucous carcinoma (OVC) is an uncommon variant of well-differentiated squamous cell carcinoma with an excellent prognosis. Epithelial dysplasia in OVC is a sign of a poorer prognosis.
Md. Akhtaruzzaman +4 more
doaj +1 more source
Clinical and Experimental Hypertension, 2023 Background Subclinical atherosclerosis may be seen at an early age of ankylosing spondylitis (AS). Syndecan 1 (S1) expression is increased in response to proinflammatory cytokine and inflammation.
Pinar Diydem Yilmaz +5 more
doaj +1 more source
The FEBS Journal, EarlyView.We describe the CD9 interactome in epithelial cells for the first time. The interactome is diverse and dynamic and changes dependent on infection with specific bacteria. We validate these data by showing functional interaction between CD9 with CD44 or CD147. We therefore demonstrate that CD9 is a universal organiser of bacterial adhesion platforms able
Paige A. Wolverson +5 more
wiley +1 more source
A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure [PDF]
, 2017 Aims: It is unclear whether distinct pathophysiological processes are present among patients with acute heart failure (AHF), with and without diabetes.
Bloomfield, Daniel M. +17 more
core +2 more sources
The endothelial glycocalyx in syndecan-1 deficient mice [PDF]
Microvascular Research, 2013 The existence of a hydrodynamically relevant endothelial glycocalyx has been established in capillaries, venules, and arterioles in vivo. The glycocalyx is thought to consist primarily of membrane-bound proteoglycans with glycosaminoglycan side-chains, membrane-bound glypicans, and adsorbed plasma proteins.
Michele D, Savery +3 more
openaire +2 more sources
Immunohistochemical analysis of syndecan-1 in leukoplakia and oral submucous fibrosis
Dental Research Journal, 2013 Background: Syndecan-1 is abundant in normal tissues and reduced in squamous cell carcinomas. Leukoplakia and oral submucous fibrosis (OSF) are oral pre-cancerous disorders that have potential for malignant transformation.
Sushant S Kamat, G S Kumar, Ajit V Koshy
doaj +1 more source
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
The FEBS Journal, EarlyView.Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Two subsets of circulating Ly6C lo monocytes distinguished by CD138 (syndecan-1) expression and Nr4a1 dependence in pristane-treated mice [PDF]
, 2022 Shuhong Han +3 more
openalex +1 more source
Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma
The FEBS Journal, EarlyView.Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris +2 more
wiley +1 more source
Immunohistochemical expression of heparanase isoforms and syndecan-1 proteins in colorectal adenomas
European Journal of Histochemistry, 2016 The proteoglycan syndecan-1 and the endoglucuronidases heparanase-1 and heparanase-2 are involved in molecular pathways that deregulate cell adhesion during carcinogenesis.
J. Waisberg +6 more
doaj +1 more source