Results 151 to 160 of about 24,222,086 (313)
Interaction of RANTES with syndecan-1 and syndecan-4 expressed by human primary macrophages
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2003 Interaction of RANTES with its membrane ligands or receptors transduces multiple intracellular signals. Whether RANTES uses proteoglycans (PGs) belonging to the syndecan family to attach to primary cells expressing RANTES G-protein-coupled receptors (GPCRs) was investigated. We demonstrate that RANTES specifically binds to high and low affinity binding Slimani, Hocine, Charnaux, Nathalie, Mbemba, Elisabeth, Saffar, Line, Vassy, Roger, Vita, Claudio, Gattegno, Liliane +6 moreopenaire +2 more sourcesImpaired nitric oxide‐dependent endothelial function in young male individuals with obesity before the onset of symptoms and complications
Experimental Physiology, EarlyView.Abstract
Endothelial dysfunction drives obesity‐related complications. Doppler ultrasound measurement of blood flow during 1‐min passive leg movements (PLM) is a valuable non‐invasive tool for assessing endothelial function and nitric oxide (NO)‐mediated vasodilation.Lucrezia Zuccarelli, Giovanni Baldassarre, Adele Bondesan, Diana Caroli, Roberta De Micheli, Gabriella Tringali, Thomas Favaretto, Joanna Suraj‐Prazmowska, Anna Kurpinska, Joanna Majerczak, Stefan Chlopicki, Jerzy A. Zoladz, Alessandro Sartorio, Bruno Grassi +13 morewiley +1 more sourceChapter Five. Systematic review results by biomarker classifications [PDF]
, 2016 5.1 Markers of Absorption and Permeability Overview
5.2 Markers of Absorption
5.3 Markers of Permeability
5.4 Markers of Digestion
5.5 Markers of Intestinal Inflammation and Intestinal Immune Activation
5.6 Markers of Systemic Inflammation and Systemic ...Denno, Donna M, Musser, Christine A, Nelson, Zakia C, Tarr, Phillip I, VanBuskirk, Kelley M +4 morecore +1 more sourceCoronin-1C Protein and Caveolin Protein Provide Constitutive and Inducible Mechanisms of Rac1 Protein Trafficking [PDF]
, 2015 Sustained directional fibroblast migration requires both polarized activation of the protrusive signal, Rac1, and redistribution of inactive Rac1 from the rear of the cell so that it can be redistributed or degraded.Barrientos, Bass, Bass, Bridgewater, Castro-Castro, Christopher A.M. Cowell, Danen, de Kreuk, Del Pozo, del Pozo, del Pozo, Echtermeyer, Elfenbein, Föger, Goetz, Grande-García, Hassanain, Itoh, James A. Roper, Kwon, Liu, Lynch, Machacek, Makarem, Mark D. Bass, Nethe, Nomanbhoy, Ojeda, Price, Prieto-Sánchez, Raftopoulou, Razani, Rosalind C. Williamson, Rosentreter, Sharma, Shaw, Spoerl, Thomas C.S. Rendall, Thomas Reville, Visvikis, Wang, Williamson, Xavier +42 morecore +1 more sourceCD138 (syndecan-1) expression in health and disease.
Histology and histopathology, 2014 CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions. In adult human tissues, CD138 is predominantly expressed in epithelial cells and plasmacytes.Palaiologou, Marina, Delladetsima, Ioanna, Tiniakos, Dina +2 moreopenaire +4 more sourcesTranscriptional Adaptations to Muscle Loading in a Murine Model of Achilles Tendinopathy
Journal of Orthopaedic Research, Volume 44, Issue 2, February 2026.ABSTRACT
Achilles tendinopathy limits mobility and decreases quality of life. Physical therapy (eccentric muscle loading) improves tendon function; however, the underlying mechanisms are unknown. This study investigated the effect of load magnitude and treatment duration in a mouse Achilles tendinopathy model.Dylan C. Easley, Bruno C. Menarim, Robert W. Grange, P. Gunnar Brolinson, Vincent M. Wang, Linda A. Dahlgren +5 morewiley +1 more sourceRemote Pancreatic Response to Severe Polytrauma Correlates With Clinical Outcome
United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.ABSTRACT Background
Acute pancreatic injury can result from blunt or sharp force trauma, often leading to serious complications. While direct pancreatic trauma is associated with high rates of infection, organ failure, and mortality, little is known about the pancreas as a potential secondary target and remote trauma organ and thereby as a booster of ...Rebecca Halbgebauer, Lisa Wohlgemuth, Jonas Wrba, Sonja Braumüller, Enes Kumral, Ludmila Lupu, Clara Morgenstern, Lucas Bettac, Sebastian Wiese, Benjamin Mayer, Paolo Cinelli, Daniel Rittirsch, Hans‐Christoph Pape, Francesco Roselli, Thomas Seufferlein, Alexander Kleger, Markus Breunig, Markus Huber‐Lang +17 morewiley +1 more sourceHeparan sulfate proteoglycans: structure, protein interactions and cell signaling [PDF]
, 2009 Heparan sulfate proteoglycans are ubiquitously found at the cell surface and extracellular matrix in all the animal species. This review will focus on the structural characteristics of the heparan sulfate proteoglycans related to protein interactions ...ABRAMSSON A, ALEXOPOULOU AN, ALLIEL PM, ALMEIDA PC, ARICESCU AR, ASHIKARI-HADA S, ATHANASSIADES A, AVIEZER D, BAEG GH, BAKER AB, BARTLETT AH, BEAUVAIS DM, BECKETT K, BELFORD DA, BELLIN R, BELTING M, BEN-ZAKEN O, BERNFIELD M, BEZAKOVA G, BLACKHALL FH, BOUCHE G, Caio V. Regatieri, CAIZERGUES-FERRER M, CAMPBELL EJ, CANO-GAUCI DF, CAPILA I, CAPILA I, CAPILA I, CAPURRO MI, CARDIN AD, CARNERO A, CASSARO CM, CASU B, CHAVANTE SF, CHEN CL, CHENG F, CHUANG WL, COHEN MM JR, COLE GJ, CONRAD HE, COOMBE DR, CROWN SE, CZUBAYKO F, DEANGELIS PL, DERKSEN PW, DIETRICH CP, DIETRICH CP, DIETRICH CP, DIETRICH CP, DIETRICH CP, DIETZ F, DUCHESNE L, ESCRIBA PV, FAN TC, FARACH-CARSON MC, FARACH-CARSON MC, FEARS CY, FEDARKO NS, FERREIRA TM, FERRO DR, FEYZI E, FILMUS J, FILMUS J, FJELDSTAD K, FOX AN, FRANCO CR, FRANSSON LA, FRANSSON LA, FUKI IV, FUKI IV, FURUKAWA K, GAGLIARDI M, GALLAGHER JT, GAMBARINI AG, GIROS A, GITAY-GOREN H, GLASS DJ, GOMES PB, GRUNERT M, GUERRINI M, GUERRINI M, GUMIENNY TL, HABUCHI H, HACKER U, HANDEL TM, HARMER NJ, HARRISON CA, HAUSSER HJ, Helena B. Nader, HENKE CA, HILEMAN RE, HSIA E, HUBER R, IOZZO RV, IOZZO RV, ISHIHARA M, ISHIHARA M, ISHITSUKA R, JASTREBOVA N, JERONIMO SM, JIANG X, JOHNSON KG, JOHNSON Z, Juliana L. Dreyfuss, JURY EC, KAYED H, KEMP LE, KIRKPATRICK CA, KNOX SM, KOOPMANN W, KREUGER J, KRILLEKE D, LAU EK, LEICHT DT, LEWIS KA, LINDNER JR, LOO BM, LOPES CC, LOPES CC, LORTAT-JACOB H, Lucia O. Sampaio, MA YQ, MIYAZONO K, MOBLI M, MOHAMMADI M, MOHAMMADI M, MONGIAT M, MOREIRA CR, MORGAN MR, MULLOY B, MULLOY B, MULLOY B, MURRAY AJ, NADER HB, NADER HB, NADER HB, NADER HB, NADER HB, NADER HB, NAKADA M, NASCIMENTO FD, NASCIMENTO FD, NG YS, NGO ST, NOTI C, NOZIK-GRAYCK E, NUGENT MA, NUNES SS, OBA-SHINJO SM, OH ES, PADERA R, PANKONIN MS, PARISH CR, PATEL VN, PATEY SJ, PELLEGRINI L, PERETTI T, POON GM, PORCIONATTO MA, PORCIONATTO MA, PORCIONATTO MA, POWELL AK, POWERS CJ, PRESTA M, QUARTO N, RAGAZZI M, RAMAN R, RAPRAEGER AC, RAPRAEGER AC, Renan P. Cavalheiro, RIDER CC, ROHDE LH, ROLNY C, RUBIN JS, RUHRBERG C, SAITO Y, SAKSELA O, SAMPAIO L, SANDERSON RD, SASAKI N, SASAKI S, SASISEKHARAN R, SCHNEPP A, SCHWALL RH, SHINJO SK, SMIRNOV SP, SONCIN F, SONG HH, SPIVAK-KROIZMAN T, STIGLIANO I, STRAUS AH, STRINGER SE, SU G, SUAREZ ER, SUGAYA N, SULPICE E, TANTRAVAHI RV, TAYLOR KR, TELCI D, TERSARIOL IL, TERSARIOL IL, Thais R. Jarrouge, TKACHENKO E, TKACHENKO E, TOLEDO OM, TOUROVSKAIA A, TRAISTER A, UTANI A, VEIGA SS, VEUGELERS M, VEUGELERS M, VIVES RR, VLODAVSKY I, WALKER A, WATT SM, WHITELOCK JM, WIEDLOCHA A, WILCOX-ADELMAN SA, WILKINS-PORT CE, WILLIAMS S, WOJTAL KA, WOODS A, WU DQ, YATES EA, YAYON A, YU WH, YU WH, ZHANG F +227 morecore +2 more sourcesIdentification of SDC1 as a Key Regulator and Therapeutic Target in Rheumatoid Arthritis via JAK2‐STAT3 Pathway
International Journal of Rheumatic Diseases, Volume 29, Issue 2, February 2026.ABSTRACT Introduction
Rheumatoid arthritis (RA) is a chronic autoimmune disorder with unclear molecular mechanisms, complicating early diagnosis and treatment. This study aimed to identify hub genes and pathways driving RA pathogenesis and assess their therapeutic potential.Gan Cao, Zhihui Wu, Yatao Du, Dongxue Dai, Yang Sun, Xi Jia, Huixin Cai +6 morewiley +1 more source
