Results 1 to 10 of about 10,821 (218)

Characterization of wooden breast myopathy: a focus on syndecans and ECM remodeling [PDF]

Frontiers in Physiology, 2023
Introduction: The skeletal muscle deformity of commercial chickens (Gallus gallus), known as the wooden breast (WB), is associated with fibrotic myopathy of unknown etiology.
Lucie Pejšková, Sissel Beate Rønning, Matthew Peter Kent, Nina Therese Solberg, Vibeke Høst, To Thu-Hien, Jens Petter Wold, Marianne Lunde, Ellen Mosleth, Addolorata Pisconti, Svein Olav Kolset, Cathrine Rein Carlson, Mona Elisabeth Pedersen   +12 more
doaj   +2 more sources

Wooden breast myopathy is characterized by satellite cell dysfunction and syndecan-4 shedding

Frontiers in Physiology
IntroductionSkeletal muscle satellite cells (MuSCs or stem cells) play a crucial role in muscle development, maintenance, and regeneration, supporting both hypertrophy and regenerative myogenesis.
Lucie Pejšková, Addolorata Pisconti, Marianne Lunde, Ka Yi Ho, Nina Therese Solberg, Shiori Koga, Erik Tengstrand, Cathrine Rein Carlson, Mona Elisabeth Pedersen, Sissel Beate Rønning   +9 more
doaj   +2 more sources

Syndecan receptors: pericellular regulators in development and inflammatory disease [PDF]

Open Biology, 2021
The syndecans are the major family of transmembrane proteoglycans, usually bearing multiple heparan sulfate chains. They are present on virtually all nucleated cells of vertebrates and are also present in invertebrates, indicative of a long evolutionary ...
Sandeep Gopal, Samantha Arokiasamy, Csilla Pataki, James R. Whiteford, John R. Couchman   +4 more
doaj   +1 more source

Syndecans in Alzheimer’s disease: pathogenetic mechanisms and potential therapeutic targets [PDF]

Neural Regeneration Research
Carmela Rita Balistreri, Roberto Monastero   +1 more
doaj   +2 more sources

Fibulin-4 and latent-transforming growth factor beta-binding protein-4 interactions with syndecan-2 and syndecan-3 are required for elastogenesis. [PDF]

FASEB J
Hakami H, Dinesh NEH, Nelea V, Lamarche-Vane N, Ricard-Blum S, Reinhardt DP.   +5 more
europepmc   +3 more sources

Syndecans and Pancreatic Ductal Adenocarcinoma

Biomolecules, 2021
Pancreatic Ductal Adenocarcinoma (PDAC) is a fatal disease with poor prognosis because patients rarely express symptoms in initial stages, which prevents early detection and diagnosis.
Nausika Betriu, Juan Bertran-Mas, Anna Andreeva, Carlos E. Semino   +3 more
doaj   +1 more source

Syndecans in Inflammation at a Glance

Frontiers in Immunology, 2020
Syndecans are transmembrane proteoglycans with heparan and chondroitin sulfate chains attached to their extracellular domain. Like many proteoglycans, they interact with a large number of ligands, such as growth factors, adhesion receptors, soluble small
Sandeep Gopal
doaj   +1 more source

Extended disorder at the cell surface: The conformational landscape of the ectodomains of syndecans

Matrix Biology Plus, 2021
Syndecans are membrane proteoglycans regulating extracellular matrix assembly, cell adhesion and signaling. Their ectodomains can be shed from the cell surface, and act as paracrine and autocrine effectors or as competitors of full-length syndecans.
Frank Gondelaud, Mathilde Bouakil, Aurélien Le Fèvre, Adriana Erica Miele, Fabien Chirot, Bertrand Duclos, Adam Liwo, Sylvie Ricard-Blum   +7 more
doaj   +1 more source

Syndecans and Their Synstatins: Targeting an Organizer of Receptor Tyrosine Kinase Signaling at the Cell-Matrix Interface

Frontiers in Oncology, 2021
Receptor tyrosine kinases (RTKs) and integrin matrix receptors have well-established roles in tumor cell proliferation, invasion and survival, often functioning in a coordinated fashion at sites of cell-matrix adhesion.
Alan C. Rapraeger
doaj   +1 more source

HA and HS Changes in Endothelial Inflammatory Activation

Biomolecules, 2021
Cardiovascular diseases are a group of disorders caused by the presence of a combination of risk factors, such as tobacco use, unhealthy diet and obesity, physical inactivity, etc., which cause the modification of the composition of the vessel’s matrix ...
Elena Caravà, Paola Moretto, Ilaria Caon, Arianna Parnigoni, Alberto Passi, Evgenia Karousou, Davide Vigetti, Jessica Canino, Ilaria Canobbio, Manuela Viola   +9 more
doaj   +1 more source