Results 121 to 130 of about 11,102 (261)

CLEC18A interacts with sulfated glycosaminoglycans and controls clear cell renal cell carcinoma progression

open access: yesThe FEBS Journal, Volume 293, Issue 3, Page 709-728, February 2026.
CLEC18A is a previously poorly characterized C‐type lectin. We mapped the expression of CLEC18A to the proximal tubule of the kidney and found CLEC18A to interact with sulfated glycosaminoglycans on proteoglycans. Furthermore, we found that CLEC18A plays an important role in hindering the progression of clear cell renal cell carcinomas in humans and in
Gustav Jonsson   +10 more
wiley   +1 more source

The influence of tethered epidermal growth factor on connective tissue progenitor colony formation [PDF]

open access: yes, 2009
Strategies to combine aspirated marrow cells with scaffolds to treat connective tissue defects are gaining increasing clinical attention and use. In situations such as large defects where initial survival and proliferation of transplanted connective ...
Au, Ada   +6 more
core   +1 more source

Bacterial porphyrins in healthy skin: Microbiota components impact melanogenesis and age‐related processes leading to Porphyr'ageing

open access: yesInternational Journal of Cosmetic Science, Volume 48, Issue 1, Page 186-199, February 2026.
Porphyrins, previously linked only to acne inflammation, are now implicated in skin ageing. Their presence correlates with increased melanin, inflammation, and oxidative stress, contributing to premature ageing signs. This study introduces the concept of “Porphyr'ageing,” highlighting the detrimental effects of bacterial metabolites on skin health and ...
Marie Meunier   +9 more
wiley   +1 more source

Pleiotrophin/Midkine Pathway Is Dysregulated in a TDP‐43A315T Mouse Model of Amyotrophic Lateral Sclerosis (ALS)

open access: yesNeuropathology, Volume 46, Issue 1, February 2026.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease (MND) characterized by progressive degeneration of both upper and lower motor neurons, along with skeletal muscles innervated by them. The identification of key molecules involved in disease pathology remains crucial for ALS, as no curative treatment is currently available ...
Paloma Martínez‐Alesón   +3 more
wiley   +1 more source

Accentuating and opposing factors leading to development of thoracic aortic aneurysms not due to genetic or inherited conditions

open access: yesFrontiers in Cardiovascular Medicine, 2015
Understanding and unraveling the pathophysiology of thoracic aortic aneurysm (TAA), a vascular disease with a potentially high mortality rate, is one of the next frontiers in vascular biology. The processes leading to the formation of TAA that are not of
Simon W Rabkin
doaj   +1 more source

Syndecan-4–dependent Rac1 regulation determines directional migration in response to the extracellular matrix [PDF]

open access: bronze, 2007
Mark D. Bass   +9 more
openalex   +1 more source

Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4 [PDF]

open access: bronze, 2010
Dianhua Jiang   +14 more
openalex   +1 more source

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