Results 31 to 40 of about 11,102 (261)

Syntenin-knock out reduces exosome turnover and viral transduction

Scientific Reports, 2021
Exosomal transfers represent an important mode of intercellular communication. Syntenin is a small scaffold protein that, when binding ALIX, can direct endocytosed syndecans and syndecan cargo to budding endosomal membranes, supporting the formation of ...
Rudra Kashyap, Marielle Balzano, Benoit Lechat, Kathleen Lambaerts, Antonio Luis Egea-Jimenez, Frédérique Lembo, Joanna Fares, Sofie Meeussen, Sebastian Kügler, Anton Roebroek, Guido David, Pascale Zimmermann   +11 more
doaj   +1 more source

Syndecans as Cell Surface Receptors in Cancer Biology. A focus on their interaction with PDZ domain proteins.

Frontiers in Pharmacology, 2016
Syndecans are transmembrane receptors with ectodomains that are modified by glycosaminoglycan chains. The ectodomains can interact with a wide variety of molecules, including growth factors, cytokines, proteinases, adhesion receptors, and extracellular ...
Bill eCheng, Marine eMontmasson, Laurent eTerradot, Patricia eRousselle   +3 more
doaj   +1 more source

CD9 co-operation with syndecan-1 is required for a major staphylococcal adhesion pathway

mBio, 2023
Epithelial colonization is a critical first step in bacterial pathogenesis. Staphylococcus aureus can utilize several host factors to associate with cells, including α5β1 integrin and heparan sulfate proteoglycans, such as the syndecans.
Luke R. Green, Rahaf Issa, Fawzyah Albaldi, Lucy Urwin, Ruth Thompson, Henna Khalid, Claire E. Turner, Barbara Ciani, Lynda J. Partridge, Peter N. Monk   +9 more
doaj   +1 more source

Heparan sulfate proteoglycans: structure, protein interactions and cell signaling [PDF]

, 2009
Heparan sulfate proteoglycans are ubiquitously found at the cell surface and extracellular matrix in all the animal species. This review will focus on the structural characteristics of the heparan sulfate proteoglycans related to protein interactions ...
ABRAMSSON A, ALEXOPOULOU AN, ALLIEL PM, ALMEIDA PC, ARICESCU AR, ASHIKARI-HADA S, ATHANASSIADES A, AVIEZER D, BAEG GH, BAKER AB, BARTLETT AH, BEAUVAIS DM, BECKETT K, BELFORD DA, BELLIN R, BELTING M, BEN-ZAKEN O, BERNFIELD M, BEZAKOVA G, BLACKHALL FH, BOUCHE G, Caio V. Regatieri, CAIZERGUES-FERRER M, CAMPBELL EJ, CANO-GAUCI DF, CAPILA I, CAPILA I, CAPILA I, CAPURRO MI, CARDIN AD, CARNERO A, CASSARO CM, CASU B, CHAVANTE SF, CHEN CL, CHENG F, CHUANG WL, COHEN MM JR, COLE GJ, CONRAD HE, COOMBE DR, CROWN SE, CZUBAYKO F, DEANGELIS PL, DERKSEN PW, DIETRICH CP, DIETRICH CP, DIETRICH CP, DIETRICH CP, DIETRICH CP, DIETZ F, DUCHESNE L, ESCRIBA PV, FAN TC, FARACH-CARSON MC, FARACH-CARSON MC, FEARS CY, FEDARKO NS, FERREIRA TM, FERRO DR, FEYZI E, FILMUS J, FILMUS J, FJELDSTAD K, FOX AN, FRANCO CR, FRANSSON LA, FRANSSON LA, FUKI IV, FUKI IV, FURUKAWA K, GAGLIARDI M, GALLAGHER JT, GAMBARINI AG, GIROS A, GITAY-GOREN H, GLASS DJ, GOMES PB, GRUNERT M, GUERRINI M, GUERRINI M, GUMIENNY TL, HABUCHI H, HACKER U, HANDEL TM, HARMER NJ, HARRISON CA, HAUSSER HJ, Helena B. Nader, HENKE CA, HILEMAN RE, HSIA E, HUBER R, IOZZO RV, IOZZO RV, ISHIHARA M, ISHIHARA M, ISHITSUKA R, JASTREBOVA N, JERONIMO SM, JIANG X, JOHNSON KG, JOHNSON Z, Juliana L. Dreyfuss, JURY EC, KAYED H, KEMP LE, KIRKPATRICK CA, KNOX SM, KOOPMANN W, KREUGER J, KRILLEKE D, LAU EK, LEICHT DT, LEWIS KA, LINDNER JR, LOO BM, LOPES CC, LOPES CC, LORTAT-JACOB H, Lucia O. Sampaio, MA YQ, MIYAZONO K, MOBLI M, MOHAMMADI M, MOHAMMADI M, MONGIAT M, MOREIRA CR, MORGAN MR, MULLOY B, MULLOY B, MULLOY B, MURRAY AJ, NADER HB, NADER HB, NADER HB, NADER HB, NADER HB, NADER HB, NAKADA M, NASCIMENTO FD, NASCIMENTO FD, NG YS, NGO ST, NOTI C, NOZIK-GRAYCK E, NUGENT MA, NUNES SS, OBA-SHINJO SM, OH ES, PADERA R, PANKONIN MS, PARISH CR, PATEL VN, PATEY SJ, PELLEGRINI L, PERETTI T, POON GM, PORCIONATTO MA, PORCIONATTO MA, PORCIONATTO MA, POWELL AK, POWERS CJ, PRESTA M, QUARTO N, RAGAZZI M, RAMAN R, RAPRAEGER AC, RAPRAEGER AC, Renan P. Cavalheiro, RIDER CC, ROHDE LH, ROLNY C, RUBIN JS, RUHRBERG C, SAITO Y, SAKSELA O, SAMPAIO L, SANDERSON RD, SASAKI N, SASAKI S, SASISEKHARAN R, SCHNEPP A, SCHWALL RH, SHINJO SK, SMIRNOV SP, SONCIN F, SONG HH, SPIVAK-KROIZMAN T, STIGLIANO I, STRAUS AH, STRINGER SE, SU G, SUAREZ ER, SUGAYA N, SULPICE E, TANTRAVAHI RV, TAYLOR KR, TELCI D, TERSARIOL IL, TERSARIOL IL, Thais R. Jarrouge, TKACHENKO E, TKACHENKO E, TOLEDO OM, TOUROVSKAIA A, TRAISTER A, UTANI A, VEIGA SS, VEUGELERS M, VEUGELERS M, VIVES RR, VLODAVSKY I, WALKER A, WATT SM, WHITELOCK JM, WIEDLOCHA A, WILCOX-ADELMAN SA, WILKINS-PORT CE, WILLIAMS S, WOJTAL KA, WOODS A, WU DQ, YATES EA, YAYON A, YU WH, YU WH, ZHANG F   +227 more
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Expression and Role of Heparan Sulfated Proteoglycans in Pancreatic Cancer

Frontiers in Oncology, 2021
Pancreatic cancer is a lethal condition with poor outcomes and an increasing incidence. The unfavourable prognosis is due to the lack of early symptoms and consequent late diagnosis.
Simone Furini, Chiara Falciani
doaj   +1 more source

Syndecans and Enzymes for Heparan Sulfate Biosynthesis and Modification Differentially Correlate With Presence of Inflammatory Infiltrate in Periodontitis

Frontiers in Physiology, 2019
Periodontitis is a common degenerative disease initiated by the bacteria in subgingival biofilm. The exposure to bacterial biofilm triggers host inflammatory response whose dysregulation is ultimately responsible for the destruction of hard and soft ...
Roko Duplancic, Marija Roguljic, Ivan Puhar, Nika Vecek, Ruzica Dragun, Katarina Vukojevic, Katarina Vukojevic, Mirna Saraga-Babic, Mirna Saraga-Babic, Darko Kero, Darko Kero   +10 more
doaj   +1 more source

Single-Cell Analysis of the Muscle Stem Cell Hierarchy Identifies Heterotypic Communication Signals Involved in Skeletal Muscle Regeneration

Cell Reports, 2020
Summary: Muscle regeneration relies on the regulation of muscle stem cells (MuSCs) through paracrine signaling interactions. We analyzed muscle regeneration in mice using single-cell RNA sequencing (scRNA-seq) and generated over 34,000 single-cell ...
Andrea J. De Micheli, Emily J. Laurilliard, Charles L. Heinke, Hiranmayi Ravichandran, Paula Fraczek, Sharon Soueid-Baumgarten, Iwijn De Vlaminck, Olivier Elemento, Benjamin D. Cosgrove   +8 more
doaj   +1 more source

Syndecan-1 enhances proliferation, migration and metastasis of HT-1080 cells in cooperation with syndecan-2. [PDF]

PLoS ONE, 2012
Syndecans are transmembrane heparan sulphate proteoglycans. Their role in the development of the malignant phenotype is ambiguous and depends upon the particular type of cancer.
Bálint Péterfia, Tibor Füle, Kornélia Baghy, Krisztina Szabadkai, Alexandra Fullár, Katalin Dobos, Fang Zong, Katalin Dobra, Péter Hollósi, András Jeney, Sándor Paku, Ilona Kovalszky   +11 more
doaj   +1 more source

Glypican-1 drives unconventional secretion of fibroblast growth factor 2

eLife, 2022
Fibroblast growth factor 2 (FGF2) is a tumor cell survival factor that is transported into the extracellular space by an unconventional secretory mechanism.
Carola Sparn, Eleni Dimou, Annalena Meyer, Roberto Saleppico, Sabine Wegehingel, Matthias Gerstner, Severina Klaus, Helge Ewers, Walter Nickel   +8 more
doaj   +1 more source

Heparan sulfate and control of cell division: adhesion and proliferation of mutant CHO-745 cells lacking xylosyl transferase [PDF]

, 2001
We have examined the role of cell surface glycosaminoglycans in cell division: adhesion and proliferation of Chinese hamster ovary (CHO) cells.
Dietrich, Carl Peter, Franco, Celia Regina Cavichlolo, Leite, Edda Lisboa, Nader, Helena Bonciani, Rocha, Hugo Alexandre Oliveira, Santos, Isabel Anunciacao Neves dos, Trindade, Edvaldo da Silva, Veiga, Silvio Sanches   +7 more
core   +2 more sources