Results 61 to 70 of about 10,821 (218)

Syndecan-4 in Tumor Cell Motility [PDF]

, 2021
Anikó Keller-Pintér, Szuzina Gyulai-Nagy, Dániel Becsky, A László, László Rovó   +4 more
openalex   +1 more source

Heparin-binding growth-associated molecule (HB-GAM) in activity-dependent neuronal plasticity in hippocampus [PDF]

, 2005
Cell adhesion and extracellular matrix (ECM) molecules play a significant role in neuronal plasticity both during development and in the adult. Plastic changes in which ECM components are implicated may underlie important nervous system functions, such ...
Pavlov, Ivan
core   +1 more source

Spatial Transcriptomics and snRNA‐seq Expose CAF Niches Orchestrating Dual Stromal‐Immune Barriers in Hepatocellular Carcinoma

Advanced Science, EarlyView.
HmmyCAFs may form a triple immunosuppressive niche: possibly secrete ECM (POSTN, etc.) as physical barriers to block CD8⁺ T cells, induce CD8⁺ T exhaustion via those molecules, and use HIF‐1α‐driven metabolism to create acidic, nutrient‐poor microenvironments that suppress T cells.
Yingxue Li, Changxiang Huan, Haoting Sun, Wei Zhang, Zhen Guo, Chuanyu Li, Jia Yao, Zhiqi Zhang, Shizhe Yu, Qiongzhu Dong, Lunxiu Qin, Jinze Li, Lianqun Zhou   +12 more
wiley   +1 more source

Novel interactions of transglutaminase-2 with heparan sulphate proteoglycans: reflection on physiological implications [PDF]

, 2008
This mini-review brings together information from publications and recent conference proceedings that have shed light on the biological interaction between transglutaminase-2 and heparan sulphate proteoglycans. We subsequently draw hypothesis of possible
A Scarpellini, A. Scarpellini, AC Parsons, AD Cardin, B Mearns, C Zehe, DC Sane, DC Sane, E Verderio, E Verderio, E. A. M. Verderio, EA Verderio, ES Oh, F Echtermeyer, F Echtermeyer, G Fan, H Morita, J Filmus, J Hang, JF Qiu, JR Bishop, K Ishiguro, K Small, L Fesus, L Lorand, L Lorand, L Pellegrini, M Griffin, M Griffin, M Signorini, MA Stepp, MR Morgan, NJ Skill, P Grenard, P Stephens, PH Seeberger, Q Fan, R Gallo, RJ Richards, S Gambetti, S Yung, SA Wilcox-Adelman, SS Akimov, T. S. Johnson, TS Johnson, TS Johnson, TS Johnson, TS Johnson, V Gentile, X Li, XD Ren, ZA Haroon   +51 more
core   +1 more source

Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?

Arthritis &Rheumatology, Accepted Article.
Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify non‐invasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin, Leonardo Palazzo, Agnes B. Fogo, Mark Haas, David R. W. Jayne, Liz Lightstone, Brad H. Rovin, Surya V. Seshan, Augusto Vaglio, Ioannis Parodis, Ingeborg M. Bajema, The LN classification steering committee   +11 more
wiley   +1 more source

Comparison of the Effects of Sevoflurane and Desflurane on Endothelial Glycocalyx in Patients Undergoing Laparoscopic Hysterectomy: A Randomized, Double-Blind Trial

Turkish Journal of Anaesthesiology and Reanimation
Objective: Various enzymes, reactive oxygen species, inflammatory conditions, and major surgeries cause endothelial glycocalyx breakdown. Inhalation of anaesthetic agents may have protective effects on the endothelium.
Kemal Tolga Saraçoğlu, Tahsin Şimşek, Hande Gürbüz, Fatih Doğu Geyik, Ebru Kale, Kürşad Nuri Baydili, Raghad Giuma M. Kordi, Ahmet Kale, Ayten Saraçoğlu   +8 more
doaj   +1 more source

Physiological and anatomical aspects of the reproduction of mice with reduced Syndecan-1 expression

Reproductive Biology and Endocrinology, 2019
Background Syndecan-1 is a heparan sulfate proteoglycan acting as a co-receptor for cytokines and growth factors mediating developmental, immunological and angiogenic processes.
Christina Gougoula, Alexandra P. Bielfeld, Sarah J. Pour, Jan-S. Krüssel, Martin Götte, W. Peter M. Benten, Dunja M. Baston-Büst   +6 more
doaj   +1 more source

Circulating Levels of the Heparan Sulfate Proteoglycan Syndecan-4 Positively Associate with Blood Pressure in Healthy Premenopausal Women

Biomolecules, 2021
Syndecans (SDCs) are transmembrane proteins that are present on most cell types where they play a role in multiple physiological processes, including cell–matrix adhesion and inflammation.
Maria De Luca, David R. Bryan, Gary R. Hunter   +2 more
doaj   +1 more source

Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby

Developmental Dynamics, EarlyView.
Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe, Yu Chen, Geoff Shaw, Marilyn B. Renfree   +3 more
wiley   +1 more source

Inhibition of PDGF-B induction and cell growth by syndecan-1 involves the ubiquitin and SUMO-1 ligase, Topors. [PDF]

PLoS ONE, 2012
Syndecans are receptors for soluble ligands, including heparin-binding growth factors, and matrix proteins. However, intracellular targets of syndecan-1 (Sdc-1)-mediated signaling are not fully understood. A yeast two-hybrid protein interaction screening
Kathleen R Braun, Allison M DeWispelaere, Steven L Bressler, Nozomi Fukai, Richard D Kenagy, Lihua Chen, Alexander W Clowes, Michael G Kinsella   +7 more
doaj   +1 more source