Results 81 to 90 of about 10,821 (218)

Control of cell division in the adult brain by heparan sulfates in fractones and vascular basement membranes [PDF]

open access: yes, 2010
Regulation of cell division in adult tissues and organs requires the coordination of growth factors at the surface of potentially-dividing cells in specific anatomic loci named germinal niches.
Frederic Mercier, Vanessa Douet
core   +1 more source

Bioengineered Extracellular Vesicles in Emerging Cancer Vaccine Platforms

open access: yesSmall Science, EarlyView.
This review highlights recent advances in engineering extracellular vesicles (EVs) as next‐generation cancer vaccines. It outlines their biological roles and antigen‐presenting capacity, explores key strategies for antigen loading and delivery optimization, and summarizes preclinical and clinical applications using EVs from diverse immune and tumor ...
Wonkyung Ahn   +4 more
wiley   +1 more source

Glycosaminoglycans are involved in bacterial adherence to lung cells

open access: yesBMC Infectious Diseases, 2017
Background Lower respiratory infections are among the top ten causes of death worldwide. Since pathogen to cell adhesion is a crucial step in the infection progress, blocking the interaction between eukaryotic receptors and bacterial ligands may enable ...
Olga Rajas   +6 more
doaj   +1 more source

Studies on the sperm reservoir of the pig oviduct [PDF]

open access: yes, 2003
During sperm transport in the female pig a proportion of spermatozoa are arrested, often for 24 h or more, in a particular segment of the utero-tubal junction (UTJ) and the adjacent tubal isthmus, where a sperm reservoir (SR) is built up.
Tienthai, Paisan
core  

FKBP5 Mediates Alveolar Fibroblast Necroptosis During Acute Respiratory Distress Syndrome

open access: yesCell Proliferation, EarlyView.
Structure diagram of alveolar fibroblast activation in septic ARDS model. FKBP5‐mediated alveolar fibroblast necroptosis, leading to the activation of NF‐κB signalling and the secretion of cytokines and the recruitment of neutrophils, and further orchestrating the inflammatory environment of the alveolar epithelia in septic ARDS.
Dong Zhang   +9 more
wiley   +1 more source

Syndecan-3 is selectively pro-inflammatory in the joint and contributes to antigen-induced arthritis in mice [PDF]

open access: yes, 2014
INTRODUCTION: Syndecans are heparan sulphate proteoglycans expressed by endothelial cells. Syndecan-3 is expressed by synovial endothelial cells of rheumatoid arthritis (RA) patients where it binds chemokines, suggesting a role in leukocyte trafficking ...
Boyes, C   +8 more
core   +4 more sources

Principal mechanisms of extracellular matrix‐mediated cell–cell communication in physiological and tumor microenvironments

open access: yesThe FEBS Journal, EarlyView.
Intracellular communication controls the processing of generated signals so that every cell type can successfully respond. The extracellular matrix (ECM) is a fundamental regulator of cell communication and signaling through the strict orchestration and functions of its bioactive components.
Zoi Piperigkou   +6 more
wiley   +1 more source

Thyroid hormone treated astrocytes induce maturation of cerebral cortical neurons through modulation of proteoglycan levels [PDF]

open access: yes, 2013
Proper brain neuronal circuitry formation and synapse development is dependent on specific cues, either genetic or epigenetic, provided by the surrounding neural environment. Within the sesignals, thyroid hormones (T3 and T4) play crucial role in several
Araujo, Ana P. B.   +6 more
core   +3 more sources

CLEC18A interacts with sulfated glycosaminoglycans and controls clear cell renal cell carcinoma progression

open access: yesThe FEBS Journal, EarlyView.
CLEC18A is a previously poorly characterized C‐type lectin. We mapped the expression of CLEC18A to the proximal tubule of the kidney and found CLEC18A to interact with sulfated glycosaminoglycans on proteoglycans. Furthermore, we found that CLEC18A plays an important role in hindering the progression of clear cell renal cell carcinomas in humans and in
Gustav Jonsson   +10 more
wiley   +1 more source

Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120

open access: yesRetrovirology, 2006
During natural HIV infection, an array of host receptors are thought to influence virus attachment and the kinetics of infection. In this study, to probe the interactions of HIV envelope (Env) with various receptors, we assessed the inhibitory properties
Wilson Ian A   +9 more
doaj   +1 more source

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