Results 91 to 100 of about 5,769,599 (338)
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Orphanet Journal of Rare DiseasesBackground Angelman syndrome (AS) is a rare neurogenetic disorder characterized by persistent cognitive and functional impairments that necessitate lifelong care.
John Jarvis +9 more
doaj +1 more source
Journal of Indian Society of Pedodontics and Preventive Dentistry, 2011 Sotos syndrome is a well-defined childhood overgrowth syndrome characterized by pre- and postnatal overgrowth, developmental delay, advanced bone age, and a typical facial gestalt including macrodolichocephaly with frontal bossing, frontoparietal ...
A Juneja, A Sultan
doaj +1 more source
Anticardiolipin syndrome: antiphospholipid syndrome [PDF]
Clinical Medicine, 2001 La detection d'anticorps antiphospholipides est a l'origine du syndrome des antiphospholipides caracterise par des pathologies vasculaires et des fausse-couches chez la femme ...
openaire +3 more sources
Overlap syndrome: A real syndrome? [PDF]
Clinical Liver Disease, 2014 Autoimmune liver diseases are rare and chronic and exert a significant burden on quality and quantity of life. The failure to understand the true etiopathogenesis of disease leaves clinicians diagnosing patients based on collective positive and negative clinical findings, such that three particular autoimmune diseases are apparent (Table 1).
Gideon M. Hirschfield, Debashis Haldar
openaire +3 more sources
A Novel DNA Repair Disorder With Thrombocytopenia, Nephrosis, and Features Overlapping Cockayne Syndrome [PDF]
, 2009 We report on four siblings with Cockayne-like syndrome with thrombocytopenia and nephrotic syndrome. The parents were healthy and consanguineous, consistent with an autosomal recessive mode of disease inheritance.
Cockayne +11 more
core +3 more sources
Molecular Oncology, EarlyView.Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef +10 more
wiley +1 more source
PERBEDAAN CAIRAN IRIGASI ANTARA Nacl 0,9% DAN STERIL WATER TERHADAP SYNDROME TRANSURETHRAL RESECTION OF PROSTATE (TURP) PADA PASIEN POST OPERASI TURP DI RS RK CHARITAS PALEMBANG [PDF]
, 2019 Background: Benign Prostatic Hyperplasia is a degenerative process that decreased testosterone and increased dihydrotestosterone. Prostate hyperplasia occurs due to constringency of the lumen, caused urinary retention.
Magdalena, Maria
core
Life events, difficulties and dilemmas in the onset of chronic fatigue syndrome: a case-control study [PDF]
, 2003 Background. The role of stress in the onset of chronic fatigue syndrome is unclear. Our objectives in this study were first, to determine the relation between the onset of chronic fatigue syndrome and stressful life events and difficulties.
Hatcher, S., House, A.
core +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source