Results 51 to 60 of about 2,222 (191)
Animal Models and Experimental Medicine, Volume 9, Issue 5, Page 947-966, May 2026.The study employed a four‐tiered strategy: (1) UHPLC‐FTMS profiling of Citrus aurantium honey to characterize its chemical composition; (2) network pharmacology analysis integrating target prediction, protein–protein interaction networks, and KEGG pathway enrichment to identify the Thor1/Nprl2‐TORC1 axis as a key mechanistic pathway; (3) in vitro ...
Wenqi Wan +6 more
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Pharmacological Research - Modern Chinese MedicineIntroduction: Alzheimer’s disease is a neurodegenerative disorder associated with cognitive decline, oxidative stress, and neuroinflammation. Synephrine, a naturally occurring alkaloid derived from traditional Chinese medicine (TCM) and commonly referred
Mohit Agrawal +5 more
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Bitter orange (Citrus aurantium L.) extract subchronic 90-day safety study in rats
Toxicology Reports, 2017 Bitter orange (Citrus aurantium L.) extracts are widely used in dietary supplements and bitter oranges are used in various juices and food products. p-Synephrine, the primary active constituent, comprises approximately 90% of total protoalkaloids.
N.S. Deshmukh +4 more
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Natural Alkaloid Compounds as Inhibitors for Alpha-Synuclein Seeded Fibril Formation and Toxicity
Molecules, 2021 The accumulation and aggregation of α-synuclein (α-syn) is the main pathologic event in Parkinson’s disease (PD), dementia with Lewy bodies, and multiple system atrophy.
Simona S. Ghanem +7 more
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Small Science, Volume 6, Issue 5, May 2026.This review comprehensively examines recent progress in MXene‐based electrochemical sensors for the detection of glucose, hydrogen peroxide, heavy metals, pesticides, nitrites, phenolic pollutants, neurotransmitters, biomarkers, and pharmaceutical compounds.
Hichem Moulahoum +3 more
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, 2005 An enantioselective LC method with photodiode array detection (PAD) was developed for the enantioseparation of synephrine from C. aurantium L. var.
BENVENUTI, Stefania +2 more
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Drug Testing and Analysis, Volume 18, Issue 4, Page 458-482, April 2026.New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
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Food Science &Nutrition, Volume 14, Issue 4, April 2026.Created in BioRender. Haralambie, O. (2025) https://BioRender.com/dh5ly89. ABSTRACT Digestive disorders such as inflammatory bowel disease (IBD) and colorectal cancer are among the most significant global health challenges, largely driven by chronic inflammation and oxidative stress.
Oana‐Roxana Haralambie, Sanda Andrei
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ChemistryOpen, Volume 15, Issue 4, April 2026.A reusable microplate platform for ultra‐high‐throughput, submicromolar separation of protonated amines – including alkyl‐, aryl‐, and aralkyl‐types – using a tris(pyridino)‐crown ether selector was introduced; the method enables rapid, zero‐energy, parallel purification fully compatible with automated synthesis workflows.
Panna Vezse +3 more
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Presence of p-synephrine in teas commercialized in Porto Alegre (RS/Brazil)
Brazilian Journal of Pharmaceutical Sciences, 2009 Citrus aurantium (bitter orange) is characterized by the presence of p-synephrine, an amine structurally and pharmacologically related to ephedrine.
Marcelo Dutra Arbo +7 more
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