Results 91 to 100 of about 15,839,975 (319)
Some ways to improve the efficiency of the enterprise management system are considered. The solution to this problem from the perspective of the synergistic approach, will allow increasing the utilization of the industrial enterprises’ potential ...
M. B. Flek +2 more
doaj +1 more source
Unusual synergistic effect in layered Ruddlesden−Popper oxide enables ultrafast hydrogen evolution
Efficient electrocatalysts for hydrogen evolution reaction are key to realize clean hydrogen production through water splitting. As an important family of functional materials, transition metal oxides are generally believed inactive towards hydrogen ...
Yinlong Zhu +10 more
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Novel Fe(III) clusters grafted Bi2MoO6 nanosheets with surface oxygen vacancies (denoted as F/BMO-SOVs) heterostructured composite have been firstly fabricated via a reliable calcination process combined with impregnation approach.
F. Fu +9 more
semanticscholar +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
This work developed a near-infrared (near-IR) light-activated non-enzymatic signal-off photoelectrochemical (PEC) immunoassay for the ultrasensitive detection of α-fetoprotein (AFP) on the basis of branched polyethylenimine (BPEI)-modified upconversion ...
Zhongbin Luo +5 more
semanticscholar +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Bao-An Chen1, Yong-Yuan Dai1, Xue-Mei Wang2, Ren-Yun Zhang2, Wen-Lin Xu3, Hui-Ling Shen3, Feng Gao1, Qian Sun1, Xiao-Jing Deng1, Jia-hua Ding1, Chong Gao1, Yun-Yu Sun1, Jian Cheng1, Jun Wang1, Gang Zhao1, Ning-Na Chen11Department of Hematology, The ...
Bao-An Chen +5 more
doaj
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

