Results 121 to 130 of about 9,524,898 (264)

The synergistic effect and mechanism of doxorubicin-ZnO nanocomplexes as a multimodal agent integrating diverse anticancer therapeutics

open access: yes, 2013
Yuxia Deng, Haijun ZhangDepartment of Oncology, Zhongda Hospital, Medical School, Southeast University, Nanjing, People's Republic of ChinaBackground: Nanomaterials have emerged as ideal multimodal nanomedicine platforms, each one combining different
Zhang H, Deng Y
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

On the synergistic effect of hydrohalic acids in the shape-controlled synthesis of anatase TiO2 single crystals

open access: yes, 2013
Cuboid-like anatase TiO2 single crystals bounded by {001} and {100} facets have been successfully synthesized with HCl as a synergistic capping agent together with HF, under the guidance of theoretical calculations.
Zhao, Huijun   +8 more
core   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Adsorption of phosphate and Cr(Ⅵ) by biochar-loaded Zn-Al layered double hydroxide

open access: yesGongye shui chuli
Reed straw biochar-loaded zinc-aluminum layered dihydroxide (ZnAl-LDHs) composites (ZnAl-LDHs@BC) were prepared by liquid-phase co-precipitation. The effects of ZnAl-LDHs mass fraction in the composite, solution pH and coexisting anions on the adsorption
YU Shui   +7 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Enriching Carbon Nanotubes in Poly (Arylene Ether Nitrile) Porous Films for Enhanced Electromagnetic Shielding Properties

open access: yesEngineered Science
The microstructure of the composite materials and the content of conductive fillers play a decisive role in the electromagnetic shielding performance. Herein, by leveraging the dispersing effect of polyvinylpyrrolidone (PVP K30) and its interaction with ...
Lingling Wang   +4 more
doaj   +1 more source

Synergistic Effect of Layered Double Hydroxides Nanodosage Form to Induce Apoptosis and Ferroptosis in Breast Cancer [PDF]

open access: yes
Siyan Pang,1,2 Chenchen Geng,1,2 Zihan Fan,2 Min Hou,1,3 Huilan Mao,1,2 Shuang Tao,1,4 Jing Wang,1,4 Yulun Wu,1,2 Ke Wei,1,4 Yunhao Li,1,2 Liuyang Yan,1,2 Qingling Yang,1,4,5 Changjie Chen,1,4,5 Wenrui Wang1,2,6 1Anhui Province Key Laboratory of ...
Yan L   +13 more
core  

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