Results 131 to 140 of about 9,524,898 (264)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The synergistic effect of hybrid flame retardants on pyrolysis behaviour of hybrid composite materials

, 2012
The aim of this investigation is to comprehensively understand the polymeric composite behavior under direct fire sources. The synergistic effects of hybrid flame retardant material on inhabiting the pyrolysis of hybrid reinforced fibers, woven roving (0°
Yousif, B. F., Albdiry, M. T., Almosawi, A. I.   +2 more
core   +1 more source

Tetrahydromagnolol targets TRIM38 to mediate PANoptosis in cancer cells and has the potential for synergistic cancer therapy

Experimental Hematology & Oncology
Background Tetrahydromagnolol (THM) is a compound isolated from Magnolia officinalis with unique chemical structure and composition. However, its anticancer effect of THM and the underlying molecular mechanisms remain unclear.
Xiaoqing Gu, Lin Li, Ting Duan, Lijun Jin, Qinsong Sheng, Quan Gao, Mengting Chen, Xinbing Sui   +7 more
doaj   +1 more source

Synergistic effect in bimetallic copper-silver (CuxAg) nanoparticles enhances silicon conversion in Rochow reaction

, 2015
The oleylamine thermal reduction process was employed to prepare bimetallic copper-silver (CuxAg (0 <= x <= 50)) nanoparticles, such as Cu, Cu50Ag, Cu20Ag, Cu10Ag, Cu5Ag, CuAg, CuAg2, and Ag, by using Cu(CH3COO)(2) and AgNO3 as the precursors ...
Zhong, Ziyi, Ji, Yongjun, Su, Fabing, Li, Jing, Zhang, Zailei   +4 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The synergistic effect of TiO2 nanoporous modification and platelet-rich plasma treatment on titanium-implant stability in ovariectomized rats

, 2016
Nan Jiang,1,2 Pinggong Du,2 Weidong Qu,2 Lin Li,2 Zhonghao Liu,2 Songsong Zhu1 1State Key Laboratory of Oral Diseases and Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 2Yantai City ...
Qu WD, Du PG, Zhu SS, Liu ZH, Jiang N, Li L   +5 more
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Emissions cap and structural adjustment11 The authors acknowledge financial support from the Natural Science Foundation of China (No. 72341008, 72341011, 72121002) and Ministry of Education Project of Key Research Institute of Humanities and Social Sciences at Universities in China (No. 22JJD790058, 22JJD790013).

China Economic Quarterly International
We use the strengthening of China's emission target control regime during the Eleventh Five-Year Plan period as a quasi-natural experiment to study the impact of strengthened environmental regulation on firm's emissions and other economic performances ...
Huanhuan Wang, Haichao Fan, Shiyi Chen
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Mutual antimicrobial effect of hibiscus acid and nalidixic acid against multidrug-resistant foodborne bacteria in CD-1 mice

Journal of Infection in Developing Countries
Introduction: The antimicrobial effect of hibiscus acid (HA) alone and in combination with nalidixic acid (NA) on multi-antibiotic-resistant Shiga-like toxin-producing Escherichia coli (STEC) and Salmonella Typhimurium (ST) was evaluated in CD-1 mice.
Esmeralda Rangel-Vargas, Reyna N Falfan-Cortés, Ma Refugio Torres-Vitela, Lizbeth A Portillo-Torres, Carlos A Gómez-Aldapa, Fabiola A Guzmán-Ortiz, Javier Castro-Rosas   +6 more
doaj   +1 more source