Results 41 to 50 of about 432,621 (308)

Responsive Exosome Nano‐bioconjugates for Synergistic Cancer Therapy

Angewandte Chemie, 2019
AbstractExosomes hold great potential in therapeutic development. However, native exosomes usually induce insufficient effects in vivo and simply act as drug delivery vehicles. Herein, we synthesize responsive exosome nano‐bioconjugates for cancer therapy.
Weidong Nie, Guanghao Wu, Jinfeng Zhang, Li‐Li Huang, Jingjing Ding, Anqi Jiang, Yahui Zhang, Yanhong Liu, Jingchao Li, Kanyi Pu, Hai‐Yan Xie   +10 more
openaire   +3 more sources

Nifurtimox Is Effective Against Neural Tumor Cells and Is Synergistic with Buthionine Sulfoximine. [PDF]

, 2016
Children with aggressive neural tumors have poor survival rates and novel therapies are needed. Previous studies have identified nifurtimox and buthionine sulfoximine (BSO) as effective agents in children with neuroblastoma and medulloblastoma.
Du, Michael, Scorsone, Kathleen A, Woodfield, Sarah E, Zage, Peter E, Zhang, Linna   +4 more
core   +1 more source

RNA-Seq Explores the Mechanism of Oxygen-Boosted Sonodynamic Therapy Based on All-in-One Nanobubbles to Enhance Ferroptosis for the Treatment of HCC

International Journal of Nanomedicine, 2022
Yichi Chen,1 Haitao Shang,1 Chunyue Wang,1 Jiaqi Zeng,2 Shentao Zhang,1 Bolin Wu,1,3 Wen Cheng1,3 1Department of Ultrasound, Harbin Medical University Cancer Hospital, Harbin, People’s Republic of China; 2School of Life Science and Technology ...
Chen Y, Shang H, Wang C, Zeng J, Zhang S, Wu B, Cheng W   +6 more
doaj  

Recent advances in syntheses and cancer treatment of cerium oxide nanoparticles

上海师范大学学报. 自然科学版, 2021
In recent years, the synthesis of cerium oxide nanoparticles(CeO2NPs) and their application in biomedicine, especially in cancer treatment, have attracted wide attention from scientists. On the one hand, with obvious cytotoxicity to cancer cells, CeO2NPs
YANG Xinyu, LIN Jiaomin, YANG Shiping
doaj   +1 more source

Reversal of gastrointestinal carcinoma-induced immunosuppression and induction of antitumoural immunity by a combination of cyclophosphamide and gene transfer of IL-12 [PDF]

, 2011
Immunotherapy-based strategies for gastrointestinal carcinomas (GIC) have been exploited so far, but these approaches have to face strong mechanisms of immune escape induced by tumours.
Alaniz, Almand, Appay, Barajas, Bell, Beyer, Bluestone, Brodsky, Bronte, Caruso, Catalina Atorrasagasti, Clark, Colombo, Colvin, Croci, Curiel, Dieckmann, Elkord, Ferlay, Flavia Piccioni, Gabrilovich, Gabrilovich, Ghiringhelli, Ghiringhelli, Gomez, Guillermo Mazzolini, Haigh, Huang, Jaime A. Espinoza, Jorge B. Aquino, Juan Bayo, Kerkar, Ko, Larmonier, Laura Alaniz, Leonard, Lorenz, Malvicini, Manuel Gidekel, Mariana Garcia, Mariana Ingolotti, Mariana Malvicini, Matar, Mazzolini, Mazzolini, Mazzolini, Medina-Echeverz, Melero, Nestle, O. Graciela Scharovsky, Onishi, Ormandy, Pablo Matar, Proietti, Putzer, Rabinovich, Sakaguchi, Sangro, Shapira, Spaapen, Suzuki, Takahashi, Tang, Thornton, Trinchieri, Vignali, Yokoyama, Zou, Zou, Zwirner   +69 more
core   +1 more source

Dual Responsive Magnetic Drug Delivery Nanomicelles with Tumor Targeting for Enhanced Cancer Chemo/Magnetothermal Synergistic Therapy

International Journal of Nanomedicine, 2023
Jianmeng Zhu,1,* Yimin Yang,2,3,* Jian Wang,1 Wenzhong Hong,1 Yiping Li,1 Zhen Wang,2 Kaiqiang Li2 1Clinical Laboratory of Chun’an First People’s Hospital, Zhejiang Provincial People’s Hospital Chun’an Branch, Hangzhou, Zhejiang, People’s ...
Zhu J, Yang Y, Wang J, Hong W, Li Y, Wang Z, Li K   +6 more
doaj  

Recent advances of copper-based nanomaterials for enhancing chemodynamic therapy

上海师范大学学报. 自然科学版, 2021
Compared with traditional treatments, chemodynamic therapy (CDT) is considered as a non-invasive treatment method with low side effects, which stands out among many treatment methods.
CHENG Yuying, ZHOU Xuesu, YAN Ge, TIAN Qiwei, YANG Shiping   +4 more
doaj   +1 more source

Efficacy of Combined 5-Fluorouracil and Photodynamic Therapy in Glioma Spheroids

, 2018
Standard treatment regimens consisting of surgery, radiation and chemotherapy have proven ineffective for the treatment of high-grade gliomas such as glioblastoma multiforme (GBM).
Singh, Karanjit
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Evaluation of melanin-targeted radiotherapy in combination with radiosensitizing drugs for the treatment of melanoma [PDF]

, 2014
The incidence of malignant melanoma is rising faster than that of any other cancer in the United States. An [131I]-labeled benzamide - [131I]MIP-1145 - selectively targets melanin, reduces melanoma tumor burden and increases survival in preclinical ...
Babich, John, Boyd, Marie, Hutchison, Sharon, Mairs, Robert, Rae, Colin, Tesson, Mathias   +5 more
core   +1 more source