Results 41 to 50 of about 821,268 (334)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Formation of a change management model in the company
Путеводитель предпринимателяIn the context of rapid changes in the external environment, organizations are faced with the need to effectively manage transformation processes in order to ensure competitiveness and achieve strategic goals.
G. R. Minasbekyan, T. V. Suvorova
doaj +1 more source
Anticipatory synergy adjustments reflect individual performance of feedforward force control [PDF]
, 2016 We grasp and dexterously manipulate an object through multi-1 digit synergy. In the framework of the uncontrolled manifold (UCM) hypothesis, multi-digit synergy is defined as the coordinated control mechanism of fingers to stabilize variable important ...
Hiroshi Imamizu, Shunta Togo
core +2 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Managing the company’s economic sustainability through website usability
Ученые записки Российской академии предпринимательстваIn today’s dynamic world, any company is concerned about maintaining its market position, increasing economic stability and competitiveness. It is known that today almost all companies have a website.
D. A. Timonov, T. V. Suvorova
doaj +1 more source
Digital transformation of business during the Fourth Industrial Revolution
Путеводитель предпринимателя, 2023 The introduction of innovative technologies, optimization of output and fundamental changes in the industrial sphere force manufacturing enterprises to find the latest sources of development and increase productivity.
V. I. Khabarov, K. V. Lukashin
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Methodological tools of consulting companies for evaluating the effectiveness of organizations.
Управленческие наукиThe article is devoted to a comparative analysis of existing opportunities and directions for evaluating the effectiveness of organizations using the resource-cost method (static model), Pareto optimality and the dynamic standard method (dynamic model).
A. A. Timofeev, A. Yu. Anisimov
doaj +1 more source
The synergy of multithreading and access/execute decoupling [PDF]
, 1999 This work presents and evaluates a novel processor microarchitecture which combines two paradigms: access/execute decoupling and simultaneous multithreading. We investigate how both techniques complement each other: while decoupling features an excellent
González Colás, Antonio María +1 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source