Results 51 to 60 of about 778,777 (287)

The synergy of multithreading and access/execute decoupling [PDF]

open access: yes, 1999
This work presents and evaluates a novel processor microarchitecture which combines two paradigms: access/execute decoupling and simultaneous multithreading. We investigate how both techniques complement each other: while decoupling features an excellent
González Colás, Antonio María   +1 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The transition of companies to innovative management as a driver for improving the stable state of organizations

open access: yesУченые записки Российской академии предпринимательства
The article examines the use of new management as a necessary condition for ensuring the sustainable state of companies in the market in the context of the digital economy. The article focuses on the application of innovations in the personnel management
A. K. Kudrin, V. I. Habarov
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Collaborations of Russian Universities with BRICS Universities: Forms, Results, Opportunities

open access: yesВысшее образование в России
The issues of effective interaction between Russian universities and universities of the BRICS countries are becoming increasingly important in practice and science today.
M. A. Lukashenko   +3 more
doaj   +1 more source

Coordination and synergy – increasing the width and depth of research in organic farming (SYNERGY) [PDF]

open access: yes, 2000
The Danish Research Centre for Organic Farming (DARCOF) is a "centre without walls", which is to say that the researchers remain in their own research environment but collaborate across institutes.

core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Methodological tools of consulting companies for evaluating the effectiveness of organizations.

open access: yesУправленческие науки
The article is devoted to a comparative analysis of existing opportunities and directions for evaluating the effectiveness  of organizations using the resource-cost method (static model), Pareto optimality and the dynamic standard method (dynamic model).
A. A. Timofeev, A. Yu. Anisimov
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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