Results 101 to 110 of about 220,441 (262)
Advanced Intelligent Systems, EarlyView.A schema‐first alignment framework builds compact, executable domain‐specific language models under data scarcity. Large‐scale synthetic question‐answer generation instills domain knowledge, and a code‐centric IR‐to‐DPO pipeline aligns generation with tool‐executable syntax.
Di Wang +4 more
wiley +1 more source
Quantifying negative selection on synonymous variants
HGG AdvancesSummary: Widespread adoption of DNA sequencing has resulted in large numbers of genetic variants, whose contribution to disease is not easily determined.
Mikhail Gudkov +2 more
doaj +1 more source
Evolution of MHC diversity in cetacean species environment: implications for the role of a pathogen [PDF]
, 2004 Previous studies have indicated that the evolution of diversity in the immune system genes responsible for antigen presentation in terrestrial mammals is driven by selection.
Vassilakos, Demetrios
core
Non-synonymous to synonymous substitution ratios of LEA paralogs.
, 2019 Non-synonymous to synonymous substitution ratios of LEA paralogs.
M. Nagaraju (1479415) +5 more
core +1 more source
Polymer Concepts in Cellular Function
Advanced Science, EarlyView.
Miao Yu +7 more
wiley +1 more source
High‐elevation endemic plants predicted to lose habitat from changing climate in Washington State
American Journal of Botany, EarlyView.Abstract Premise High‐elevation plants face unique challenges from potential climate change impacts that will likely require upslope migration into increasingly smaller suitable habitat. This situation is particularly acute for endemic species that by definition occupy small geographic ranges.
Nicholas L. Gjording +4 more
wiley +1 more source
American Journal of Community Psychology, EarlyView.Abstract Evaluations of community‐engaged research (CEnR) typically emphasize health outcomes rather than the partnership processes that contribute to intervention effectiveness. This scoping review synthesized community partner‐identified strategies for successful community‐academic health research partnerships with Black American communities and ...
Kaylyn A. Garcia +6 more
wiley +1 more source
Selection on non-synonymous mutations.
, 2013 The figure shows cumulative distributions of the observed rate of change of the allele frequencies between two consecutive samples at times and for non-synonymous polymorphisms, synonymous polymorphisms, and synonymous polymorphisms at least 100bp ...
Thomas Leitner (18756) +1 more
core +1 more source
Severe Phenotype in an Indian Family With Progressive Pseudorheumatoid Arthropathy of Childhood
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Progressive pseudorheumatoid arthropathy of childhood (PPAC) is a rare autosomal recessive progressive condition that affects the cartilage of joints and bones. The symptoms of PPAC include stiffness of the joints, bony swelling of the toes and fingers, short stature, kyphosis, and muscle weakness.
Narinder Singh +5 more
wiley +1 more source
Molecular Mechanisms and the Significance of Synonymous Mutations
BiomoleculesSynonymous mutations result from the degeneracy of the genetic code. Most amino acids are encoded by two or more codons, and mutations that change a codon to another synonymous codon do not change the amino acid in the gene product.
Peter Oelschlaeger
doaj +1 more source