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Conserved Secondary Structures in Viral mRNAs [PDF]

open access: yesViruses, 2019
RNA secondary structure in untranslated and protein coding regions has been shown to play an important role in regulatory processes and the viral replication cycle.
Michael Kiening   +5 more
doaj   +5 more sources

Secondary Structure of Chloroplast mRNAs In Vivo and In Vitro [PDF]

open access: yesPlants, 2020
mRNA secondary structure can influence gene expression, e.g., by influencing translation initiation. The probing of in vivo mRNA secondary structures is therefore necessary to understand what determines the efficiency and regulation of gene expression ...
Piotr Gawroński   +2 more
doaj   +5 more sources

Analysis of secondary structure within sgm and kgmB mRNA [PDF]

open access: yesArchives of Biological Sciences, 2010
Sgm methyltransferase from Micromonospora zionensis and KgmB methyltransferase from Streptoalloteichus tenebrarius are resistant to aminoglycoside antibiotics as a result of their ability to specifically methylate G1405 within the bacterial 16S rRNA A ...
Vojnović Sandra   +3 more
doaj   +1 more source

Secondary Structure across the Bacterial Transcriptome Reveals Versatile Roles in mRNA Regulation and Function. [PDF]

open access: yesPLoS Genetics, 2015
Messenger RNA acts as an informational molecule between DNA and translating ribosomes. Emerging evidence places mRNA in central cellular processes beyond its major function as informational entity.
Cristian Del Campo   +3 more
doaj   +1 more source

Light-Dependent Translation Change of Arabidopsis psbA Correlates with RNA Structure Alterations at the Translation Initiation Region

open access: yesCells, 2021
mRNA secondary structure influences translation. Proteins that modulate the mRNA secondary structure around the translation initiation region may regulate translation in plastids.
Piotr Gawroński   +8 more
doaj   +1 more source

Evaluation of accessible regions of Escherichia coli fimH mRNA through computational prediction and experimental investigation

open access: yesIranian Journal of Microbiology, 2021
Background and Objectives: This study aimed to investigate the accessible regions of the fimH mRNA using computational prediction and dot-blot hybridization to increase the effectiveness of antisense anti-virulence therapeutics against Uropathogenic ...
Elnaz Harifi Mood   +5 more
doaj   +1 more source

Widespread selection for extremely high and low levels of secondary structure in coding sequences across all domains of life [PDF]

open access: yesOpen Biology, 2019
Codon composition, GC content and local RNA secondary structures can have a profound effect on gene expression, and mutations affecting these parameters, even though they do not alter the protein sequence, are not neutral in terms of selection.
Daniel Gebert   +2 more
doaj   +1 more source

Single nucleotide polymorphism and bioinformatics analysis of DQA2 gene in yak

open access: yes浙江大学学报. 农业与生命科学版, 2020
Single nucleotide polymorphism (SNP) of DQA2 gene in yak was analyzed via genomic DNA pooled amplification and directly sequencing, and further the influence of SNP sites on the secondary structures of mRNA and protein of DQA2 gene were predicted and ...
LI Zhuo   +6 more
doaj   +1 more source

A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg 2+ Transporter in Salmonella Typhimurium

open access: yesmBio, 2021
Translation initiation regions in mRNAs that include the ribosome-binding site (RBS) and the start codon are often sequestered within a secondary structure.
Eunna Choi   +5 more
doaj   +1 more source

N6‐methyladenosine and RNA secondary structure affect transcript stability and protein abundance during systemic salt stress in Arabidopsis

open access: yesPlant Direct, 2020
After transcription, a messenger RNA (mRNA) is further post‐transcriptionally regulated by several features including RNA secondary structure and covalent RNA modifications (specifically N6‐methyladenosine, m6A). Both RNA secondary structure and m6A have
Marianne C. Kramer   +8 more
doaj   +1 more source

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