Results 131 to 140 of about 2,164,308 (357)

Identifying Predictive Biomarkers of Response in Patients With Rheumatoid Arthritis Treated With Adalimumab Using Machine Learning Analysis of Whole‐Blood Transcriptomics Data

open access: yesArthritis &Rheumatology, EarlyView.
Objective Tumornecrosis factor inhibitors (TNFi) have significantly improved rheumatoid arthritis (RA) management, yet variability in patient response remains a substantial challenge, with approximately 40% of patients discontinuing TNFi due to nonresponse or adverse effects.
Chuan Fu Yap   +12 more
wiley   +1 more source

Plates in synovial fluid [PDF]

open access: yesArthritis & Rheumatism, 1978
Michael Yaron, Meir Djaldetti
openaire   +3 more sources

Clonal sharing of CD8+ T‐cells links skin and joint inflammation in psoriatic arthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Psoriatic arthritis (PsA) is an HLA class I‐associated inflammatory arthritis that develops in up to 30% of people with psoriasis. We tested the hypothesis that skin and joint inflammation in PsA is linked in terms of CD8+ T‐cell phenotype and clonality.
Lucy E. Durham   +14 more
wiley   +1 more source

Infrapatellar fat pad adipose tissue-derived macrophages display a predominant CD11c+CD206+ phenotype and express genotypes attributable to key features of OA pathogenesis

open access: yesFrontiers in Immunology
ObjectivesIn knee osteoarthritis (OA), macrophages are the most predominant immune cells that infiltrate synovial tissues and infrapatellar fat pads (IPFPs).
Patchanika Hengtrakool   +13 more
doaj   +1 more source

Monocyte‐derived macrophages‐synovial fibroblasts crosstalk unravels oncostatin signaling network as a driver of synovitis in osteoarthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Osteoarthritis (OA) is a debilitating joint disease characterized by cartilage degradation, synovial inflammation, and pain. Macrophages have been implicated in OA pathology, but the origins and functions of diverse macrophage subsets seeding the synovial joint tissue remain incompletely understood.
Damien Laouteouet   +18 more
wiley   +1 more source

Collagenases in human synovial fluid [PDF]

open access: bronze, 1969
Edward D. Harris   +2 more
openalex   +1 more source

Autoantibody response towards chromatin in patients with juvenile idiopathic arthritis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Juvenile idiopathic arthritis (JIA) patients frequently exhibit antinuclear antibodies (ANAs), but the specific antigen target recognized by them and the presence of additional autoantibody specificities in JIA patients remains elusive. Methods Plasma samples from 110 untreated patients with active JIA, as well as from 14 children with ...
Viola Pitkänen   +13 more
wiley   +1 more source

Behaviour of synovial fluid on surfaces of articular cartilage. A scanning electron microscope study. [PDF]

open access: bronze, 1969
Peter S. Walker   +5 more
openalex   +1 more source

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