Results 21 to 30 of about 76,148 (125)

Capillary-driven indentation of a microparticle into a soft, oil-coated substrate [PDF]

Soft Matter, 2020, 16, 5812, 2020
Small scale contact between a soft, liquid-coated layer and a stiff surface is common in many situations, from synovial fluid on articular cartilage to adhesives in humid environments. Moreover, many model studies on soft adhesive contacts are conducted with soft silicone elastomers, which possess uncrosslinked liquid molecules (i.e. silicone oil) when
arxiv   +1 more source

Osteoarthritic Synovial Fluid Modulates Cell Phenotype and Metabolic Behavior In Vitro

Stem Cells International, 2019
Synovial fluid holds a population of mesenchymal stem cells (MSC) that could be used for clinical treatment. Our goal was to characterize the inflammatory and metabolomic profile of the synovial fluid from osteoarthritic patients and to identify its ...
Eduardo Branco de Sousa, Gilson Costa dos Santos Junior, Ramon Pinheiro Aguiar, Rafaela da Costa Sartore, Ana Carolina Leal de Oliveira, Fabio Ceneviva Lacerda Almeida, Vivaldo Moura Neto, Diego Pinheiro Aguiar   +7 more
doaj   +1 more source

Preliminary Report: Osteoarthritis and Rheumatoid Arthritis Synovial Fluid Increased Osteoclastogenesis In Vitro by Monocyte Differentiation Pathway Regulating Cytokines

Mediators of Inflammation, 2022
Background. Rheumatoid arthritis (RA) and osteoarthritis (OA) are common joint diseases associated with changes in local, as well as systemic bone structure and osteoclast function.
Jani Luukkonen, Johanna Huhtakangas, Sanna Palosaari, Juha Tuukkanen, Olli Vuolteenaho, Petri Lehenkari   +5 more
doaj   +1 more source

Children with oligoarticular juvenile idiopathic arthritis have skewed synovial monocyte polarization pattern with functional impairment—a distinct inflammatory pattern for oligoarticular juvenile arthritis

Arthritis Research & Therapy, 2020
Background Juvenile idiopathic arthritis (JIA) is an umbrella term of inflammatory joint diseases in children. Oligoarthritis is the most common form in the Western world, representing roughly 60% of all patients.
Tobias Schmidt, Elisabet Berthold, Sabine Arve-Butler, Birgitta Gullstrand, Anki Mossberg, Fredrik Kahn, Anders A. Bengtsson, Bengt Månsson, Robin Kahn   +8 more
doaj   +1 more source

Evidence of acrolein in synovial fluid of dogs with osteoarthritis as a potential inflammatory biomarker

BMC Musculoskeletal Disorders, 2021
Background Acrolein is a known pro-inflammatory toxic aldehyde, propagating cellular damage and tissue inflammation in humans and animal models of various diseases.
Seth A. Herr, Sarah Malek, Mark C. Rochat, George E. Moore, Jeff C. Ko, Riyi Shi   +5 more
doaj   +1 more source

Statistical method for analysis of interactions between chosen protein and chondroitin sulfate in an aqueous environment [PDF]

, 2022
We present the statistical method to study the interaction between a chosen protein and another molecule (e.g., both being components of lubricin found in synovial fluid) in a water environment. The research is performed on the example of univariate time series of chosen features of the dynamics of mucin, which interact with chondroitin sulfate (4 and ...
arxiv   +1 more source

Dextrose Prolotherapy for Symptomatic Grade IV Knee Osteoarthritis: A Pilot Study of Early and Longer-Term Analgesia and Pain-Specific Cytokine Concentrations

Clinics and Practice, 2022
Background: Neurocytokines may upregulate or downregulate neuropathic pain. We hypothesized that dextrose (D-glucose) injections for therapeutic purposes (dextrose prolotherapy: DPT) in painful knee osteoarthritis (KOA) would favorably affect synovial ...
Gastón Andrés Topol, Ines Guerrero Pestalardo, Kenneth Dean Reeves, Fernando Elias, Neven J. Steinmetz, An-Lin Cheng, David Rabago   +6 more
doaj   +1 more source

Synovial fluid IL-1β appears useful for the diagnosis of chronic periprosthetic joint infection

Journal of Orthopaedic Surgery and Research, 2021
Purpose The purpose of this study was to investigate the role of synovial fluid interleukin (IL)-1β in diagnosing chronic periprosthetic joint infection (PJI) and to identify the optimal threshold of synovial fluid IL-1β for differentiating chronic PJI ...
Hai Wang, Leilei Qin, Jiawei Wang, Wei Huang   +3 more
doaj   +1 more source

Elasticity and relaxation properties of oral fluid [PDF]

arXiv, 2021
The research is aimed at creating a method for rheological testing of viscoelastic fluids, the droplets of which, when stretched, form thinning filaments, i.e. exhibit the property of spinning. The typical example of such fluid is oral fluid (or mixed saliva). Among other things, the rheological features of the oral fluid actively affect the mechanisms
arxiv  

Optimized “In Vitro” Culture Conditions for Human Rheumatoid Arthritis Synovial Fibroblasts

Mediators of Inflammation, 2014
The composition of synovial fluid in rheumatoid arthritis (RA) is complex and strongly influences the microenvironment of joints and it is an inseparable element of the disease.
Claudia Casnici, Donatella Lattuada, Noemi Tonna, Katia Crotta, Claudio Storini, Fabio Bianco, Marcello Claudio Truzzi, Costantino Corradini, Ornella Marelli   +8 more
doaj   +1 more source