Results 21 to 30 of about 2,164,308 (357)

Investigation of synovial fluid lubricants and inflammatory cytokines in the horse: a comparison of recombinant equine interleukin 1 beta-induced synovitis and joint lavage models

BMC Veterinary Research, 2021
Background Lameness is a debilitating condition in equine athletes that leads to more performance limitation and loss of use than any other medical condition.
Amanda Watkins, Diana Fasanello, Darko Stefanovski, Sydney Schurer, Katherine Caracappa, Albert D’Agostino, Emily Costello, Heather Freer, Alicia Rollins, Claire Read, Jin Su, Marshall Colville, Matthew Paszek, Bettina Wagner, Heidi Reesink   +14 more
doaj   +1 more source

Neutrophil extracellular trap clearance by synovial macrophages in gout

Arthritis Research & Therapy, 2021
Background Monosodium urate (MSU) crystals, i.e., the central etiological factors in gouty arthritis, induce the formation of neutrophil extracellular traps (NETs).
Ji Hye Jeong, Su Jin Choi, Soo Min Ahn, Ji Seon Oh, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo, Seokchan Hong   +7 more
doaj   +1 more source

Quantification of chondroitin sulfate, hyaluronic acid and N-glycans in synovial fluid – A technical performance study

Osteoarthritis and Cartilage Open, 2023
Objective: To validate a quantitative high performance liquid chromatography (HPLC) assay for chondroitin sulfate (CS) and hyaluronic acid (HA) in synovial fluid, and to analyze glycan-patterns in patient samples.
Elin Andersson, Emil Tykesson, L. Stefan Lohmander, Niclas G. Karlsson, Chunsheng Jin, Ekaterina Mirgorodskaya, Per Swärd, André Struglics   +7 more
doaj   +1 more source

Hyperlipidemic microenvironment conditionates damage mechanisms in human chondrocytes by oxidative stress

Lipids in Health and Disease, 2017
Background Currently, two pathogenic pathways describe the role of obesity in osteoarthritis (OA); one through biomechanical stress, and the other by the contribution of systemic inflammation.
Daniel Medina-Luna, Mónica Guadalupe Santamaría-Olmedo, Yessica Zamudio-Cuevas, Karina Martínez-Flores, Javier Fernández-Torres, Gabriela Angélica Martínez-Nava, Denise Clavijo-Cornejo, Cristina Hernández-Díaz, Anell Olivos-Meza, Luis Enrique Gomez-Quiroz, María Concepción Gutiérrez-Ruiz, Carlos Pineda, Francisco Blanco, Anthony M. Reginato, Alberto López-Reyes   +14 more
doaj   +1 more source

Comparative biochemical analysis of synovial fluid constituents in infected cases following total knee replacement [PDF]

Гений oртопедии, 2019
Introduction Biochemical parameters of synovial fluid constituents were reviewed in patients prior to total knee replacement (TKR). The diagnostic value of certain biochemical tests was identified as prognostic factors in the development of infection ...
Elena L. Matveeva, Zinaida S. Naumenko, Elena S. Spirkina, Anna G. Gasanova, Irina A. Talashova, Anastasia A. Rakhmatulina   +5 more
doaj   +1 more source

A Systemic and Local Comparison of Senescence in an Acute Anterior Cruciate Ligament Injury—A Pilot Case Series

Life, 2023
Background: Senescence, a characteristic of cellular aging and inflammation, has been linked to the acceleration of osteoarthritis. The purpose of this study is to prospectively identify, measure, and compare senescent profiles in synovial fluid and ...
Robert A. Waltz, Kaitlyn E. Whitney, Victoria R. Duke, Heidi Kloser, Charles Huard, Matthew T. Provencher, Marc J. Philippon, Chelsea Bahney, Jonathan A. Godin, Johnny Huard   +9 more
doaj   +1 more source

Fast Morphological Gallbladder Changes Triggered by a Hypercholesterolemic Diet

Annals of Hepatology, 2018
Introduction and aim. Obesity is a worldwide epidemic problem, described as a risk factor for hepatic diseases, such as non-alcoholic fatty liver disease and other pathologies related to development of cholesterol crystals and cholesterol gallbladder ...
Alberto López-Reyes, Denise Clavijo-Cornejo, Javier Fernández-Torres, Daniel Medina-Luna, Erendida G. Estrada-Villaseñor, Luis E. Gómez-Quiroz, Marwin Gutiérrez, Julio Granados, Gilberto Vargas-Alarcón, Carlos Pineda, Hiram García, Luis A Morales-Garza, María C. Gutiérrez-Ruiz, Karina Martínez-Flores   +13 more
doaj   +1 more source

The concordance between preoperative aspiration and intraoperative synovial fluid culture results: intraoperative synovial fluid re-cultures are necessary whether the preoperative aspiration culture is positive or not

BMC Infectious Diseases, 2021
Aims Preoperative aspiration culture and intraoperative cultures play pivotal roles in periprosthetic joint infection (PJI) diagnosis and pathogen identification.
Hao Li, Chi Xu, LiBo Hao, Wei Chai, Fu Jun, Jiying Chen   +5 more
doaj   +1 more source

Synovial fluid presepsin as a novel biomarker for the rapid differential diagnosis of native joint septic arthritis from crystal arthritis

International Journal of Infectious Diseases, 2021
Objective: To investigate whether presepsin can be used as a novel biomarker to differentiate between native joint septic arthritis (NJSA) and crystal arthritis (CA). Methods: This study included 75 patients diagnosed with either NJSA (n = 21) or CA (n =
Takashi Imagama, Kazushige Seki, Toshihiro Seki, Atsunori Tokushige, Yuta Matsuki, Kazuhiro Yamazaki, Daisuke Nakashima, Tomoya Okazaki, Kenji Hirata, Manabu Yamamoto, Hiroshi Tanaka, Takashi Sakai   +11 more
doaj   +1 more source

Hyaluronic acid synthesis, degradation, and crosslinking in equine osteoarthritis: TNF-α-TSG-6-mediated HC-HA formation

Arthritis Research & Therapy, 2021
Background TNF-α-stimulated gene 6 (TSG-6) protein, a TNF-α-responsive hyaladherin, possesses enzymatic activity that can catalyze covalent crosslinks of the polysaccharide hyaluronic acid (HA) to another protein to form heavy chain-hyaluronic acid (HC ...
Diana C. Fasanello, Jin Su, Siyu Deng, Rose Yin, Marshall J. Colville, Joshua M. Berenson, Carolyn M. Kelly, Heather Freer, Alicia Rollins, Bettina Wagner, Felipe Rivas, Adam R. Hall, Elaheh Rahbar, Paul L. DeAngelis, Matthew J. Paszek, Heidi L. Reesink   +15 more
doaj   +1 more source