Results 41 to 50 of about 70,874 (312)

Evidence of acrolein in synovial fluid of dogs with osteoarthritis as a potential inflammatory biomarker

BMC Musculoskeletal Disorders, 2021
Background Acrolein is a known pro-inflammatory toxic aldehyde, propagating cellular damage and tissue inflammation in humans and animal models of various diseases.
Seth A. Herr, Sarah Malek, Mark C. Rochat, George E. Moore, Jeff C. Ko, Riyi Shi   +5 more
doaj   +1 more source

Single Molecule Microscopy Reveals an Increased Hyaluronan Diffusion Rate in Synovial Fluid from Knees Affected by Osteoarthritis. [PDF]

, 2016
Osteoarthritis is a common and progressive joint disorder. Despite its widespread, in clinical practice only late phases of osteoarthritis that are characterized by severe joint damage are routinely detected.
Ahmad, SS, Kohlhof, Hendrik, Kaminski, Tim P, Schmolders, Jan, Rommelspacher, Yorck, Randau, Thomas, Gravius, Sascha, Kohl, S, Friedrich, Max   +8 more
core   +1 more source

Children with oligoarticular juvenile idiopathic arthritis have skewed synovial monocyte polarization pattern with functional impairment—a distinct inflammatory pattern for oligoarticular juvenile arthritis

Arthritis Research & Therapy, 2020
Background Juvenile idiopathic arthritis (JIA) is an umbrella term of inflammatory joint diseases in children. Oligoarthritis is the most common form in the Western world, representing roughly 60% of all patients.
Tobias Schmidt, Elisabet Berthold, Sabine Arve-Butler, Birgitta Gullstrand, Anki Mossberg, Fredrik Kahn, Anders A. Bengtsson, Bengt Månsson, Robin Kahn   +8 more
doaj   +1 more source

Healthy human synovial fluid. [PDF]

, 2018
Healthy human synovial fluid.
Lars Bräuer (287741), Nadine Hartjen (5774528), Brigitte Müller-Hilke (3160920), Mary B. Goldring (234026), Thomas Müller (3554), Horst Claassen (830393), Michael Tsokos (5774534), Friedrich Paulsen (44377), Fabian Garreis (457616), Kolja Gelse (5774540), Beate Reiß (5774531), Stephanie Beileke (830392), Sebastian Hoogeboom (4512346), Martin Schicht (287742), Saskia Etzold (5774537)   +14 more
core   +1 more source

Assessment of synovial joint fluid [PDF]

, 2016
Assessment of synovial joint fluid is a simple, cheap, and relatively non-invasive test that can be applied to the whole spectrum of joint diseases, provided there is sufficient fluid within the joint to aspirate.
DC Mangham, Anthony J. Freemont, Engy Abdelattif   +2 more
core   +1 more source

Synovial fluid IL-1β appears useful for the diagnosis of chronic periprosthetic joint infection

Journal of Orthopaedic Surgery and Research, 2021
Purpose The purpose of this study was to investigate the role of synovial fluid interleukin (IL)-1β in diagnosing chronic periprosthetic joint infection (PJI) and to identify the optimal threshold of synovial fluid IL-1β for differentiating chronic PJI ...
Hai Wang, Leilei Qin, Jiawei Wang, Wei Huang   +3 more
doaj   +1 more source

Synovial fluid metabolites in osteonecrosis [PDF]

, 2007
Objectives. Osteonecrosis of the femoral head results from interruption of the vascular supply and eventual death of the cellular portion of bone. Effective methods of monitoring response to treatment are needed.
Bowers, J. R., Huebner, J. L., Urbaniak, J. R., Kraus, V. B., Huffman, K. M., Dailiana, Z.   +5 more
core   +1 more source

Structural Guidance in 3D Microgel‐in‐Hydrogel Systems to Improve Chondrogenesis

Advanced Healthcare Materials, EarlyView.
The Anisogel, an anisotropic microgel‐in‐hydrogel system, guides chondrogenic differentiation of human mesenchymal stromal cells (hMSCs) modulated by the alignment and size of anisometric microgels. Chondrogenic markers are upregulated in an in vitro model and guided tissue infiltration is enhanced in a semi‐orthopedic mouse model due to the physico ...
Julia Kamp, Alisa C. Suturin, Claudia A. Garrido, Xiaole Tong, Jietao Xu, Nicole Kops, Lea‐Sophie Müller, Till Hülsmann, Abdolrahman Omidinia‐Anarkoli, Laura Klasen, Tamás Haraszti, Gerjo J. V. M. van Osch, Laura De Laporte   +12 more
wiley   +1 more source

Dextrose Prolotherapy for Symptomatic Grade IV Knee Osteoarthritis: A Pilot Study of Early and Longer-Term Analgesia and Pain-Specific Cytokine Concentrations

Clinics and Practice, 2022
Background: Neurocytokines may upregulate or downregulate neuropathic pain. We hypothesized that dextrose (D-glucose) injections for therapeutic purposes (dextrose prolotherapy: DPT) in painful knee osteoarthritis (KOA) would favorably affect synovial ...
Gastón Andrés Topol, Ines Guerrero Pestalardo, Kenneth Dean Reeves, Fernando Elias, Neven J. Steinmetz, An-Lin Cheng, David Rabago   +6 more
doaj   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source