Results 31 to 40 of about 1,338,566 (303)

A Systemic and Local Comparison of Senescence in an Acute Anterior Cruciate Ligament Injury—A Pilot Case Series

Life, 2023
Background: Senescence, a characteristic of cellular aging and inflammation, has been linked to the acceleration of osteoarthritis. The purpose of this study is to prospectively identify, measure, and compare senescent profiles in synovial fluid and ...
Robert A. Waltz, Kaitlyn E. Whitney, Victoria R. Duke, Heidi Kloser, Charles Huard, Matthew T. Provencher, Marc J. Philippon, Chelsea Bahney, Jonathan A. Godin, Johnny Huard   +9 more
doaj   +1 more source

Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin [PDF]

, 2005
Pathological processes involved in the initiation of rheumatoid synovitis remain unclear. We undertook the present study to identify immune and stromal processes that are present soon after the clinical onset of rheumatoid arthritis ( RA) by assessing a ...
Lee, CY, Gordon, C, Buckley, Christopher, Emma J Ross, Lord, JM, Raza, K, Raza, Karim, S John Curnow, Ross, EJ, Salmon, Michael, Falciani, F, Lord, Janet; id_orcid, Mike Salmon, Caroline Gordon, Christopher D Buckley, Falciani, Francesco, Karim Raza, Buckley, CD, Janet M Lord, Akbar, AN, Lee, C-Y, Francesco Falciani, Ross, Emma, Arne N Akbar, Curnow, Stephen, Chi-Yeung Lee, Salmon, M, Gordon, Caroline, Curnow, SJ   +28 more
core   +1 more source

The concordance between preoperative aspiration and intraoperative synovial fluid culture results: intraoperative synovial fluid re-cultures are necessary whether the preoperative aspiration culture is positive or not

BMC Infectious Diseases, 2021
Aims Preoperative aspiration culture and intraoperative cultures play pivotal roles in periprosthetic joint infection (PJI) diagnosis and pathogen identification.
Hao Li, Chi Xu, LiBo Hao, Wei Chai, Fu Jun, Jiying Chen   +5 more
doaj   +1 more source

Quantification of chondroitin sulfate, hyaluronic acid and N-glycans in synovial fluid – A technical performance study

Osteoarthritis and Cartilage Open, 2023
Objective: To validate a quantitative high performance liquid chromatography (HPLC) assay for chondroitin sulfate (CS) and hyaluronic acid (HA) in synovial fluid, and to analyze glycan-patterns in patient samples.
Elin Andersson, Emil Tykesson, L. Stefan Lohmander, Niclas G. Karlsson, Chunsheng Jin, Ekaterina Mirgorodskaya, Per Swärd, André Struglics   +7 more
doaj   +1 more source

Comparative biochemical analysis of synovial fluid constituents in infected cases following total knee replacement [PDF]

Гений oртопедии, 2019
Introduction Biochemical parameters of synovial fluid constituents were reviewed in patients prior to total knee replacement (TKR). The diagnostic value of certain biochemical tests was identified as prognostic factors in the development of infection ...
Elena L. Matveeva, Zinaida S. Naumenko, Elena S. Spirkina, Anna G. Gasanova, Irina A. Talashova, Anastasia A. Rakhmatulina   +5 more
doaj   +1 more source

Synovial fluid presepsin as a novel biomarker for the rapid differential diagnosis of native joint septic arthritis from crystal arthritis

International Journal of Infectious Diseases, 2021
Objective: To investigate whether presepsin can be used as a novel biomarker to differentiate between native joint septic arthritis (NJSA) and crystal arthritis (CA). Methods: This study included 75 patients diagnosed with either NJSA (n = 21) or CA (n =
Takashi Imagama, Kazushige Seki, Toshihiro Seki, Atsunori Tokushige, Yuta Matsuki, Kazuhiro Yamazaki, Daisuke Nakashima, Tomoya Okazaki, Kenji Hirata, Manabu Yamamoto, Hiroshi Tanaka, Takashi Sakai   +11 more
doaj   +1 more source

Characterization of the porcine synovial fluid proteome and a comparison to the plasma proteome

Data in Brief, 2015
Synovial fluid is present in all joint cavities, and protects the articular cartilage surfaces in large by lubricating the joint, thus reducing friction. Several studies have described changes in the protein composition of synovial fluid in patients with
Tue Bjerg Bennike, Omar Barnaby, Hanno Steen, Allan Stensballe   +3 more
doaj   +1 more source

Hyaluronic acid synthesis, degradation, and crosslinking in equine osteoarthritis: TNF-α-TSG-6-mediated HC-HA formation

Arthritis Research & Therapy, 2021
Background TNF-α-stimulated gene 6 (TSG-6) protein, a TNF-α-responsive hyaladherin, possesses enzymatic activity that can catalyze covalent crosslinks of the polysaccharide hyaluronic acid (HA) to another protein to form heavy chain-hyaluronic acid (HC ...
Diana C. Fasanello, Jin Su, Siyu Deng, Rose Yin, Marshall J. Colville, Joshua M. Berenson, Carolyn M. Kelly, Heather Freer, Alicia Rollins, Bettina Wagner, Felipe Rivas, Adam R. Hall, Elaheh Rahbar, Paul L. DeAngelis, Matthew J. Paszek, Heidi L. Reesink   +15 more
doaj   +1 more source

Investigation on the Influence of Synovial Fluid and Vitreous Humour on Avulsion Wounds Healing in Rabbits [PDF]

Archives of Razi Institute, 2021
In the present study, we investigated the efficacy of vitreous humour and synovial fluid on avulsion wound healing in a rabbit’s model. The vitreous humour is a fluid that resembles gel consisting of approximately 98–99% water, little hyaluronic acid ...
L. A Naeem, Z. B Abdul Kareem, M. M Jassim, A. A Khalaf, Z. A Jabbar   +4 more
doaj   +1 more source

Osteoarthritic Synovial Fluid Modulates Cell Phenotype and Metabolic Behavior In Vitro

Stem Cells International, 2019
Synovial fluid holds a population of mesenchymal stem cells (MSC) that could be used for clinical treatment. Our goal was to characterize the inflammatory and metabolomic profile of the synovial fluid from osteoarthritic patients and to identify its ...
Eduardo Branco de Sousa, Gilson Costa dos Santos Junior, Ramon Pinheiro Aguiar, Rafaela da Costa Sartore, Ana Carolina Leal de Oliveira, Fabio Ceneviva Lacerda Almeida, Vivaldo Moura Neto, Diego Pinheiro Aguiar   +7 more
doaj   +1 more source