Results 51 to 60 of about 70,874 (312)

Review of the Tribological Characteristics of Synovial Fluid [PDF]

, 2016
Movement of the knee joint requires an effective lubrication mechanism. Synovial fluid is reported to serve this function. Synovial fluid is an extra cellular biofluid present in the synovial joint of living beings.
Prekasan, D., Saju, K.K.
core   +1 more source

Therapeutic Extracellular Vesicles from Synovial Fibroblast‐Primed MSCs for Osteoarthritis Treatment

Advanced Healthcare Materials, EarlyView.
EVs derived from the microenvironment of SFs transferred MSCs (miSF‐MSC‐EVs) enhanced the expression of miRNAs that regulate cell migration, cell adhesion, and the TGF‐β signaling pathway, demonstrating superior anti‐inflammatory and cartilage regeneration effects compared to conventional MSC‐EVs.
Seo Jeong Kim, Ji Seob Kim, Min Hee Moon, Jae‐Hyeok Jang, In Sun Hwang, Byung‐Hyun Cha   +5 more
wiley   +1 more source

Optimized “In Vitro” Culture Conditions for Human Rheumatoid Arthritis Synovial Fibroblasts

Mediators of Inflammation, 2014
The composition of synovial fluid in rheumatoid arthritis (RA) is complex and strongly influences the microenvironment of joints and it is an inseparable element of the disease.
Claudia Casnici, Donatella Lattuada, Noemi Tonna, Katia Crotta, Claudio Storini, Fabio Bianco, Marcello Claudio Truzzi, Costantino Corradini, Ornella Marelli   +8 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Experimental study and model for healthy and pathological synovial fluid [PDF]

, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Kastrinakis, EG, Goudoulas, TB, 3rd Micro and Nano Flows Conference (MNF2011)   +2 more
core  

変形性膝関節炎患者膝関節液中の細胞外マトリックス成分と可溶性VCAM-1 [PDF]

, 1997
It is generally accepted that the number of patients with osteoarthritis (OA) of the knee must increase in the future because of the increase of the aged. The pathogenic mechanisms of OA haven't been elucidated yet, but it is supposed that mediate pannus
Okamoto, Motoi, Nakata, Yasunari, Endo, Hiroshi, Sakiyama, Junko, Tohge, Hiroko, Ichimura, Mitsuko   +5 more
core   +1 more source

An Implantable Optogenetics‐Engineered Hydrogel for Amelioration of Rheumatoid Arthritis through Light‐Controlled Metabolic Reprogramming of Synovial Macrophages

Advanced Science, EarlyView.
An implantable hydrogel is designed to enable in situ and on‐demand secretion of GLP‐1 in synovium through blue light irradiation to activate GLP‐1R/HK2/VDAC1 pathway for upregulating tricarboxylic acid cycle and oxidative phosphorylation in macrophage, facilitating tissue repair and bone erosion recovery.
Dahai Hu, Yaru Sun, Qi Lu, Yi Zhang, Jieruo Li, Huige Hou, Huajun Wang, Hui Tang, Yunsong Zhang, Xiaofei Zheng, Qingsong Mei   +10 more
wiley   +1 more source

miRNA expression levels in synovial fluid. [PDF]

, 2020
miRNA expression levels in synovial fluid.
Jeong Seop Lim (8284284), Dae-Kyung Kwak (6506018), Nan Young Kim (8284281), Yun Joong Kim (3145566), Je-Hyun Yoo (3938033), Yoon Hae Kwak (8284278)   +5 more
core   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

Dental disorders are associated with minimal synovial changes in the temporomandibular joint in horses

Frontiers in Veterinary Science
IntroductionDental disorders have been proposed as factors contributing to temporomandibular joint (TMJ) discomfort in horses, but objective evidence linking these conditions to synovial fluid alterations remains limited. This study evaluated whether the
Joao Ricardo Kunz, Rubens Peres Mendes, Milena Carol Sbrussi Granella, Adson Costa, Rodrigo Romero Corrêa, Anderson Fernando de Souza, Joandes Henrique Fonteque, Silvio Kau-Strebinger   +7 more
doaj   +1 more source