Results 71 to 80 of about 70,874 (312)

Joint contact modelling of articular cartilage in synovial joints [PDF]

open access: yes, 2010
Hip joint is one of the important load bearing joints and has been extensively studied to investigate contact mechanics and tribology. It has known to experience high contact forces and stresses.
ath Shrikant, Sainath Shrikant   +1 more
core  

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

Synovial fluid analysis in companion animal medicine [PDF]

open access: yes, 2017
Synovial fluid analysis is an integral part of the diagnostic approach of joint disorders in companion animal medicine. It mainly helps the veterinarian to differentiateinflammatory from non-inflammatory and infectious from noninfectious joint diseases ...
N. N. PRASSINOS (N.N. ΠΡΑΣΙΝΟΣ)   +2 more
core   +1 more source

CD31+ Cell Enrichment Enhances Therapeutic Effects of Stromal Vascular Fraction in Experimental Primary Osteoarthritis: A Preclinical Study in the Dunkin Hartley Guinea Pig Model

open access: yesAdvanced Science, EarlyView.
Both SVF and CD31+ SVF improve spontaneous osteoarthritis, but CD31+ enrichment refines the therapeutic profile rather than broadly enhancing all effects. More distinct benefits are observed in extracellular matrix remodeling, osteochondral integrity, and subchondral/trabecular bone preservation, supporting CD31+‐enriched SVF as a biologically enhanced
Sijia Zhou   +16 more
wiley   +1 more source

Synovial Fluid Cytology

open access: yes, 2012
In the evaluation of artificial joint disorders, synovial fluid analysis can become a very efficient diagnostic tool. This chapter explains the role of synovial fluid cytological analysis in diagnosing prosthetic joint infection (PJI). Recommended cutoff values for diagnosing PJI for leukocyte count are 1,700 cells/μL and for neutrophils 65 ...
Mihalič, Rene, Terčič, Dunja
openaire   +2 more sources

Survey of synovial fluid cryoprecipitates. [PDF]

open access: yes, 1980
Synovial fluid cryoproteins from various inflammatory and noninflammatory arthritides were examined for the presence of immunoglobulin, fibrinogen, antiglobulin activity, and third component of complement and correlated with the synovial fluid leucocyte ...
Myers, A R, Ludivico, C L
core  

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

open access: yesAdvanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai   +11 more
wiley   +1 more source

Local and systemic inflammatory lipid profiling in a rat model of osteoarthritis with metabolic dysregulation. [PDF]

open access: yesPLoS ONE, 2018
Bioactive oxidised lipids (oxylipins) are important signalling mediators, capable of modulating the inflammatory state of the joint and anticipated to be of importance in joint homeostasis and status of osteoarthritis.
H M de Visser   +8 more
doaj   +1 more source

Measurements of C-reactive protein in serum and lactate dehydrogenase in serum and synovial fluid of patients with osteoarthritis [PDF]

open access: yes, 2005
Diagnosis of osteoarthritis (OA) is based upon the clinical orthopaedic examination and the radiographic assessment, both of which can be non-specific and insensitive in early joint disease. The aim of our study was to investigate if there is an increase
Schmökel, Hugo   +5 more
core   +1 more source

Cytokines in healthy temporomandibular joint synovial fluid [PDF]

open access: yes, 2014
Analysis of temporomandibular joint (TMJ) synovial fluid may elucidate the aetiology of temporomandibular disorders and arthritic conditions, as well as the inflammatory mechanisms involved.
Kristensen, KD   +5 more
core   +3 more sources

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