Results 81 to 90 of about 2,164,308 (357)

An Anti‐Myd88 Peptide Synergistically Enhances the Anti‐Inflammatory Effects of Extracellular Vesicles from Naïve Umbilical Cord MSC or HEK293F CD24 Overexpressing Cells

open access: yesAdvanced Materials Interfaces, EarlyView.
This study confirms that extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) or HEK293F cells overexpressing CD24 have anti‐inflammatory effects in macrophages and monocytes. Further loading either of these EVs with an anti‐Myd88 peptide synergistically enhanced the anti‐inflammatory effects of the EVs.
Burçin İrem Abas   +6 more
wiley   +1 more source

Advancements in Dissolving Microneedles for Effective Transdermal Delivery in Rheumatoid Arthritis Treatment

open access: yesAdvanced Materials Interfaces, EarlyView.
Rheumatoid arthritis, a chronic inflammatory joint disease, faces limitations with conventional therapies. Dissolving microneedles (DMNs) enable biocompatible, high‐capacity transdermal drug delivery. However, skin elasticity challenges their strength, limiting drug release depth.
Wangrui Peng   +4 more
wiley   +1 more source

4D Bioprinted Self‐Folding Scaffolds Enhance Cartilage Formation in the Engineering of Trachea

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A bilayer self‐folding scaffold, triggerable by humidity, is fabricated via 4D bioprinting for trachea engineering. An analytical model is derived to predict its radius of curvature, enabling its scalability. Cartilage progenitor cells seeded on the scaffold perceive scaffold final curvature and react to it, by enhancing the upregulation of pro ...
Irene Chiesa   +4 more
wiley   +1 more source

Orosomucoid 1 Ameliorates Temporomandibular Joint Osteoarthritis by Maintaining Cartilage Homeostasis

open access: yesAdvanced Science, EarlyView.
The present study identified the key protein ORM1 through the proteomic analysis of synovial fluid samples from patients with temporomandibular joint osteoarthritis (TMJOA), and demonstrated the important role of ORM1 in maintaining cartilage homeostasis via the suppression of VIM/MAPK/MMP signalling.
Dahe Zhang   +5 more
wiley   +1 more source

Thanatochemistry: Study of synovial fluid potassium

open access: yesAlexandria Journal of Medicine, 2014
Death interval estimation is one of the major attributes obtained from thanatochemistry. Body fluids like vitreous humour have been consistently used to estimate death interval from regression equations, but these may be useless when dealing with eye ...
Nilesh Keshav Tumram   +2 more
doaj   +1 more source

Research Progress on Biomaterials with Immunomodulatory Effects in Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This review highlights recent advanced in immunomodulatory biomaterials for bone repair, focusing on design strategies, immune interactions, and clinical potential. Abstract The immune system plays a pivotal role in bone regeneration, and biomaterials engineered to modulate immune responses present a promising strategy for the treatment of extensive ...
Jianan Li   +11 more
wiley   +1 more source

False-Negative Rate of Gram-Stain Microscopy for Diagnosis of Septic Arthritis: Suggestions for Improvement

open access: yesInternational Journal of Microbiology, 2014
We quantify the false-negative diagnostic rate of septic arthritis using Gram-stain microscopy of synovial fluid and compare this to values reported in the peer-reviewed literature.
Paul Stirling   +6 more
doaj   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

open access: yesAdvanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai   +5 more
wiley   +1 more source

Coupling mechanism of bioinspired artificial composite synovial fluid on the tribological behavior of artificial joints

open access: yesFriction
Changes in the components of synovial fluid in the human body have an important influence on the tribological behavior of artificial joints. Based on the concentration of components in the synovial fluid after arthroplasty, “hard−soft” joint pair ...
Jiajia Cen   +7 more
doaj   +1 more source

Influence of Synovial Fluid Pressure on Biphasic Lubrication Property in Articular Cartilage

open access: yesTribology Online, 2018
The influence of synovial fluid pressure in wedge-film gap on the biphasic lubrication property of articular cartilage during sliding motion has not been discussed in previous studies.
Shoko Horibata   +2 more
doaj   +1 more source

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