Results 11 to 20 of about 2,392,786 (296)

Synovial membrane asks for independence

Folia Morphologica, 2014
Synovial membrane is traditionally considered as a part of the joint capsule. It, however, differs from fibrous part of the capsule in development, structure, function, vascularisation, innervation and involvement in pathological processes. Moreover, in some areas, it even does not contact with the fibrous capsule.
S, Moskalewski, A, Osiecka-Iwan, E, Jankowska-Steifer, A, Hyc   +3 more
core   +5 more sources

Gene Expression Pattern of Cells From Inflamed and Normal Areas of Osteoarthritis Synovial Membrane [PDF]

Arthritis & Rheumatology, 2014
To compare the gene expression patterns of synovial cells from inflamed or normal/reactive areas of synovial membrane obtained from the same patient with osteoarthritis (OA).
C. Lambert, J. Dubuc, E. Montell, J. Vergés, C. Munaut, A. Noël, Y. Henrotin   +6 more
semanticscholar   +2 more sources

Differential cartilaginous tissue formation by human synovial membrane, fat pad, meniscus cells and articular chondrocytes [PDF]

, 2007
Objective: To identify an appropriate cell source for the generation of meniscus substitutes, among those which would be available by arthroscopy of injured knee joints.
A. Marsano, Jakob, M., I. Martin, E. Kon, Tognana, E., Nehrer, S., D.M. Salter, E. Tognana, Marsano, A., Adesida, A., Hardingham, T., Salter, D.M., S.J. Millward-Sadler, Salter, D. M., A. Adesida, S. Nehrer, T. Hardingham, Chiari-Grisar, C., Kon, E., Martin, I., Millward-Sadler, S. J., M. Jakob, C. Chiari-Grisar, Millward-Sadler, S.J.   +23 more
core   +1 more source

Comparison of exosomes secreted by induced pluripotent stem cell-derived mesenchymal stem cells and synovial membrane-derived mesenchymal stem cells for the treatment of osteoarthritis

Stem cell research & therapeutics, 2017
BackgroundOsteoarthritis (OA) is the most common joint disease worldwide. In the past decade, mesenchymal stem cells (MSCs) have been used widely for the treatment of OA.
Yu Zhu, Yuchen Wang, Bizeng Zhao, X. Niu, Bin Hu, Qing Li, Juntao Zhang, Jian Ding, Yunfeng Chen, Yang Wang   +9 more
semanticscholar   +1 more source

Fusobacterium nucleatum aggravates rheumatoid arthritis through FadA-containing outer membrane vesicles.

Cell Host and Microbe, 2023
Rheumatoid arthritis (RA) is an autoimmune disorder that has been associated with the gut microbiota. However, whether and how the gut microbiota plays a pathogenic role in RA remains unexplored. Here, we observed that Fusobacterium nucleatum is enriched
Mukeng Hong, Zhuang Li, Haihua Liu, Songyuan Zheng, Fangling Zhang, Junqing Zhu, Hao Shi, Haixin Ye, Z. Chou, Lei Gao, J. Diao, Yang Zhang, Dongxin Zhang, Shixian Chen, Hongwei Zhou, Juan Li   +15 more
semanticscholar   +1 more source

A predominant Th1 polarization is present in synovial fluid of end‐stage osteoarthritic knee joints: analysis of peripheral blood, synovial fluid and synovial membrane

Clinical and Experimental Immunology, 2018
Thorough understanding of the complex pathophysiology of osteoarthritis (OA) is necessary in order to open new avenues for treatment. The aim of this study was to characterize the CD4+ T cell population and evaluate their activation and polarization ...
N. Rosshirt, S. Hagmann, E. Tripel, T. Gotterbarm, J. Kirsch, F. Zeifang, Hanns-Martin Lorenz, T. Tretter, B. Moradi   +8 more
semanticscholar   +1 more source

Synovial fibroblasts as potential drug targets in rheumatoid arthritis, where do we stand and where shall we go?

Annals of the Rheumatic Diseases, 2022
Fibroblast-like synoviocytes or synovial fibroblasts (FLS) are important cellular components of the inner layer of the joint capsule, referred to as the synovial membrane.
T. Németh, G. Nagy, T. Pap
semanticscholar   +1 more source

The Overexpression of NALP3 Inflammasome in Knee Osteoarthritis Is Associated with Synovial Membrane Prolidase and NADPH Oxidase 2

Oxidative Medicine and Cellular Longevity, 2016
Osteoarthritis is characterized by the presence of proinflammatory cytokines and reactive oxygen species. We aimed to clarify the role of prooxidant enzyme content at the synovial membrane level and how it correlates with the inflammatory process in ...
D. Clavijo-Cornejo, K. Martínez-Flores, Karina Silva-Luna, G. Martínez-Nava, J. Fernández-Torres, Y. Zamudio-Cuevas, Mónica Guadalupe Santamaría-Olmedo, Julio Granados-Montiel, C. Pineda, A. López-Reyes   +9 more
semanticscholar   +1 more source

Peptide-anchored neutrophil membrane-coated biomimetic nanodrug for targeted treatment of rheumatoid arthritis

Journal of Nanobiotechnology, 2023
Macrophage polarization determines the production of cytokines that fuel the initiation and evolution of rheumatoid arthritis (RA). Thus, modulation of macrophage polarization might represent a potential therapeutic strategy for RA.
Ni Yang, Miaomiao Li, Ling Wu, Yinhong Song, Shi Yu, Yingying Wan, Wenjing Cheng, Baoye Yang, Xiaoqing Mou, Hongfeng Yu, Jing Zheng, Xinzhi Li, Xiang Yu   +12 more
semanticscholar   +1 more source

Specific biological responses of the synovial membrane to carbon nanotubes

Scientific Reports, 2015
Biological evaluation of carbon nanotubes (CNTs) is typically performed in the lung or abdominal cavity; however, biological reactions to CNTs are predicted to be markedly different in other tissues.
Hiroki Nomura, Seiji Takanashi, Manabu Tanaka, H. Haniu, Kaoru Aoki, M. Okamoto, Shinsuke Kobayashi, T. Takizawa, Yuki Usui, Ayumu Oishi, Hiroyuki Kato, N. Saito   +11 more
semanticscholar   +1 more source