Nomenclature clarification: synovial fibroblasts and synovial mesenchymal stem cells
Synovial-derived cells, found in the synovial membrane of human joints, were obtained by digestion of the synovial membrane and were subsequently expanded in vitro. The identity of synovial-derived cells has long been a topic of debate. The terms “type B
Fangqi Li +7 more
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Systemic levels of IL-23 are strongly associated with disease activity in rheumatoid arthritis but not spondyloarthritis [PDF]
Objectives Th17 cells are an effector T-cell population that plays a role in chronic inflammatory conditions and is dependent on IL-23 for their survival and expansion. More recently, a genetic association was discovered between polymorphisms in the gene
De Keyser, Filip +8 more
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Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells [PDF]
Acute inflammation is a complex and tightly regulated homeostatic process that includes leukocyte migration from the vasculature into tissues to eliminate the pathogen/injury, followed by a pro-resolving response promoting tissue repair.
Achuthan +115 more
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Autophagy and rheumatoid arthritis: Current knowledges and future perspectives [PDF]
Autophagy is a degradation mechanism by which cells recycle cytoplasmic components to generate energy. By influencing lymphocyte development, survival, and proliferation, autophagy regulates the immune responses against self and non-self antigens ...
Alessandri, Cristiano +10 more
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Giant intra-articular synovial chondromatosis of knee joint mimicking malignancy: A rare case report
Synovial chondromatosis is a rare benign condition arising from the synovial membrane of the joints, synovial sheaths, or bursae around the joints. Primary synovial chondromatosis typically affects the large joints in the third to fifth decade of life ...
Abhijeet Ingle +3 more
doaj +1 more source
Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair [PDF]
High-fat diet-induced obesity is a major risk factor for osteoarthritis (OA) and diminished wound healing. The objective of this study was to determine the associations among serum and synovial fluid lipid levels with OA, synovitis, adipokine levels, and
Guilak, Farshid +3 more
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Some clinical aspects of rheumatoid arthritis [PDF]
In our department we have been placing a special emphasis on the treatment and study of rheumatoid arthritis, and during the last four years we have handled about 1,600 cases visiting our outpatient clinic and approximately 100 hospitalized cases.
Kodama, Toshio
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Quantification of cells expressing mesenchymal stem cell markers in healthy and osteoarthritic synovial membranes [PDF]
[Abstract] Objective. To quantify cells expressing mesenchymal stem cell (MSC) markers in synovial mem- branes from human osteoarthritic (OA) and healthy joints. Methods.
Blanco García, Francisco J +6 more
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Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana +2 more
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Association of FCGR3A and FCGR3B haplotypes with rheumatoid arthritis and primary Sjögren's syndrome [POSTER PRESENTATION] [PDF]
Background Rheumatoid arthritis (RA) is an autoimmune disease that is thought to arise from a complex interaction between multiple genetic factors and environmental triggers.
Barrett, J.H. +14 more
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