Results 201 to 210 of about 46,096 (291)

The M2 Macrophages Importance Role in Psoriasis

open access: yesImmunity, Inflammation and Disease, Volume 13, Issue 6, June 2025.
ABSTRACT Background Psoriasis is a chronic autoimmune skin condition that is increasingly prevalent globally, causing significant challenges for affected individuals. The disease is influenced by a combination of genetic factors, environmental triggers, immune system dysfunction, and its systemic nature with comorbidities like cardiovascular diseases ...
Ahmed Hussein Hasan Alshihmani   +4 more
wiley   +1 more source

Synovial membrane protein expression differs between juvenile idiopathic arthritis subtypes in early disease [PDF]

open access: gold, 2014
Sorcha Finnegan   +6 more
openalex   +1 more source

Role of Macrophage TLR4 Expression in the Immunopathogenesis of Severe Aplastic Anemia

open access: yesJournal of Clinical Laboratory Analysis, Volume 39, Issue 12, June 2025.
This study found that the high expression of TLR4 in macrophages of SAA patients was positively correlated with the sepsis level, and inhibition of TLR4 expression could reduce the macrophage sepsis level and the killing effect of CD8+ T cells, thus alleviating the over‐activated cellular immune response in SAA patients.
Mengran Gao   +6 more
wiley   +1 more source

CD4+CD25+/highCD127low/- regulatory T cells are enriched in rheumatoid arthritis and osteoarthritis joints—analysis of frequency and phenotype in synovial membrane, synovial fluid and peripheral blood [PDF]

open access: gold, 2014
Babak Moradi   +9 more
openalex   +1 more source

Silk Fibroin‐Based Hydrogels Supplemented with Decellularized Extracellular Matrix and Gelatin Facilitate 3D Bioprinting for Meniscus Tissue Engineering

open access: yesMacromolecular Bioscience, Volume 25, Issue 6, June 2025.
To engineer meniscus tissue, a combination of silk fibroin, decellularized meniscus extracellular matrix, and gelatin is 3D bioprinted with infrapatellar fat pad‐derived mesenchymal stem cells. Cell addition is found to affect the enzymatic crosslinking and the mechanical properties of the hydrogels, whose Young's modulus matches with human meniscus ...
Jennifer Fritz   +6 more
wiley   +1 more source

Bioengineered Nanozymes for Orthopedic Degenerative Diseases: From Catalytic Mechanisms to Multimodal Therapy

open access: yesMedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.
IDD and OA is caused by various mechanisms, creating a vicious cycle that impairs disc function. Nanozymes and nano‐enzyme delivery systems offer innovative therapies by targeting these underlying mechanisms, such as anti‐inflammatory therapy, ECM repair, cellular dysfunction and antioxidant therapy, providing a promising approach to restoring tissue ...
Lei Peng   +4 more
wiley   +1 more source

Unlocking T‐Cell Plasticity in the Tumor Microenvironment: Implications for Cancer Progression and Therapeutic Strategies

open access: yesMedComm – Oncology, Volume 4, Issue 2, June 2025.
The tumor microenvironment (TME) shapes T‐cell plasticity, influencing cancer progression and therapeutic outcomes. Here, we summarize the phenotypic transitions and spatial distribution of T cells within the TME, highlighting their dual roles in therapeutic efficacy and resistance.
Xiao‐Hong Ding   +4 more
wiley   +1 more source

Research Progress of Osteoarthritis Treatment by Low Intensity Pulsed Ultrasound

open access: yesSmart Medicine, Volume 4, Issue 2, June 2025.
As a non‐invasive therapeutic modality, LIPUS demonstrates potential in mitigating OA progression. This review synthesizes current evidence of OA pathophysiology, summarizes the mechanism of LIPUS treatment of OA, and proposes synergistic strategies to advanced OA treatment.
Mengtong Guan   +10 more
wiley   +1 more source

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