Results 71 to 80 of about 87,013 (233)

Synovial Fluid of Patient With Rheumatoid Arthritis Enhanced Osmotic Sensitivity Through the Cytotoxic Edema Module in Synoviocytes

Frontiers in Cell and Developmental Biology, 2021
Rheumatoid arthritis (RA) is an autoimmune disease that causes inflammation of the synovial membrane ultimately leading to permanent damage in the affected joints.
Min Jeong Ji, Min Jeong Ji, Hee Jung Ryu, Jeong Hee Hong   +3 more
doaj   +1 more source

Investigation of the role of endosomal Toll-like receptors in murine collagen-induced arthritis reveals a potential role for TLR7 in disease maintenance [PDF]

, 2012
INTRODUCTION Endosomal toll-like receptors (TLRs) have recently emerged as potential contributors to the inflammation observed in human and rodent models of rheumatoid arthritis (RA).
Alzabin, Saba, Kong, Philip, Medghalchi, Mino, Palfreeman, Andrew, Sacre, Sandra, Williams, Richard   +5 more
core   +1 more source

Fibrotic pathways and fibroblast-like synoviocyte phenotypes in osteoarthritis

Frontiers in Immunology
Osteoarthritis (OA) is the most common form of arthritis, characterized by osteophyte formation, cartilage degradation, and structural and cellular alterations of the synovial membrane.
Alexandra Damerau, Alexandra Damerau, Emely Rosenow, Dana Alkhoury, Frank Buttgereit, Frank Buttgereit, Timo Gaber, Timo Gaber   +7 more
doaj   +1 more source

KNEE CARTILAGE AND SYNOVIAL MEMBRANE STRUCTURAL CHANGES DURING TIBIA DISTRACTION WITH PLATING

Travmatologiâ i Ortopediâ Rossii, 2017
Purpose of the study — to analyze the changes in knee articular cartilage and synovial membrane during distraction external fixation of the tibia in combination with plating.Material and methods.
T. A. Stupina, M. A. Stepanov
doaj   +1 more source

Regulation of peripheral inflammation by spinal p38 MAP kinase in rats. [PDF]

, 2006
BackgroundSomatic afferent input to the spinal cord from a peripheral inflammatory site can modulate the peripheral response. However, the intracellular signaling mechanisms in the spinal cord that regulate this linkage have not been defined.
Albani, Salvatore, Boyle, David L, Firestein, Gary S, Hammaker, Deepa, Jones, Toni L, Rosengren, Sanna, Sorkin, Linda, Svensson, Camille I   +7 more
core   +3 more sources

Effect of a small molecule inhibitor of nuclear factor-κB nuclear translocation in a murine model of arthritis and cultured human synovial cells [PDF]

, 2005
A small cell-permeable compound, dehydroxymethylepoxyquinomicin (DHMEQ), does not inhibit phosphorylation and degradation of IκB (inhibitor of nuclear factor-κB [NF-κB]) but selectively inhibits nuclear translocation of activated NF-κB.
Kubota, Tetsuo, Miyasaka, Nobuyuki, Nanki, Toshihiro, Umezawa, Kazuo, Wakamatsu, Kyoko   +4 more
core   +2 more sources

ELECTRON MICROSCOPY OF THE HUMAN SYNOVIAL MEMBRANE [PDF]

The Journal of Cell Biology, 1962
The structure of the lining cells at the surface of the synovial membrane facing the joint cavity has been studied by electron microscopy. The long cytoplasmic processes of these cells appear to be oriented toward the surface of the membrane, where they overlap and intertwine.
David Hamerman, Peter Barland, Alex B. Novikoff   +2 more
openaire   +3 more sources

Effect of Toll-Like Receptor 4 on Synovial Injury of Temporomandibular Joint in Rats Caused by Occlusal Interference

Mediators of Inflammation, 2016
Synovitis is an important disease that causes intractable pain in TMJ. Some investigations suggested that the increasing expression of IL-1β secreted by synovial lining cells plays an important role in synovial inflammation and cartilage destruction in ...
Jingjing Kong, Yingying Yang, Shuzhen Sun, Jianli Xie, Xuefen Lin, Ping Ji   +5 more
doaj   +1 more source

Synovial inflammation plays a greater role in post-traumatic osteoarthritis compared to idiopathic osteoarthritis in the Hartley guinea pig knee

BMC Musculoskeletal Disorders, 2017
Background The objective of this study was to evaluate the extent of stromal cell-derived factor-1’s (SDF-1) involvement in the pathogenesis of idiopathic versus post-traumatic OA by comparing differences in synovial membrane morphology, SDF-1 synovial ...
Nathan P. Thomas, Wesley J. Wu, Braden C. Fleming, Fangyuan Wei, Qian Chen, Lei Wei   +5 more
doaj   +1 more source

Preliminary definitions for the sonographic features of synovitis in children [PDF]

, 2016
Objectives Musculoskeletal ultrasonography (US) has the potential to be an important tool in the assessment of disease activity in childhood arthritides. To assess pathology, clear definitions for synovitis need to be developed first.
Backhaus, M, Balint, P, Bruns, A, Bruyn, Ga, Collado, P, D'Agostino, Ma, De la Cruz, L, Guillaume Czitrom, S, Herlin, T, Hernandez, C, Iagnocco, Annamaria, Jousse Joulin, S, Lanni, S, Lilleby, V, Magni Manzoni, S, Malattia, C, Modesto, C, Naredo, E., Narrodi, A, Nieto, Jc, Ohrndorf, S, Ravagnani, V, Rossi, L, Roth, J, Selvaag, Am, Swen, N, Ting, T, Tzaribachev, N, Vega Fernandez, P, Vojinovic, J, Windschall, D   +30 more
core   +2 more sources