Results 51 to 60 of about 2,392,786 (296)

Tendon is covered by a basement membrane epithelium that is required for cell retention and the prevention of adhesion formation [PDF]

, 2011
The ability of tendons to glide smoothly during muscle contraction is impaired after injury by fibrous adhesions that form between the damaged tendon surface and surrounding tissues. To understand how adhesions form we incubated excised tendons in fibrin
Al-Youha Sarah, Susan H Taylor, Van Agtmael Tom, Van Agtmael, T., Wong, J., Lu Yinhui, Wong Jason, Kadler Karl E., Duncan A. McGrouther, Jason Wong, Taylor, Susan H, Kadler, Karl E; id_orcid, Al-Youha, Sarah, McGrouther, Duncan A, Agarwal, S., Duncan A McGrouther, Karl E Kadler, McGrouther Duncan A., Lu, Y., Yinhui Lu, Karl E. Kadler, Al-Youha, S., Sarah Al-Youha, Taylor Susan H., Kadler, K.E., Lu, Yinhui, Tom Van Agtmael, Taylor, S.H., McGrouther, D.A., Susan H. Taylor, Van Agtmael, Tom, Wong, Jason; id_orcid   +31 more
core   +1 more source

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

Advanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang, Yingying Wang, Lujie Yu, Chunmei Jiang, Haoyu Liu, Yaohua Chen, Shutong Wu, Qin Liu, Lingling Wei, Xiaochun Zheng, Huifang Hao, Mengting Gao, Weiwei Kang, Rong Dai, Ziliang Zheng, Ruiping Zhang   +15 more
wiley   +1 more source

Synovial joints: Mechanobiology and tissue engineering of articular cartilage and synovial fluid

, 2017
This chapter provides an overview of the components of synovial joints including articular cartilage, synovium, and synovial fluid. Focus is placed on the biomechanical properties of these tissues and models of their behavior.
Meinert, C., Sah, R.L., Klein, T.J., Raleigh, A.R., Chen, A.C., A.R. Raleigh, C. Meinert, McCarty, W.J., T.J. Klein, W.J. McCarty, A.C. Chen, R.L. Sah   +11 more
core   +1 more source

Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment

Advanced Science, EarlyView.
Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen, Jiaying Li, Jinjin Ma, Xiaonan Yuan, Yao Xiao, Yang Zhang, Yuan Chen, Hao Jiang, Hui He, Jie Hu, Qianglong Chen, Jinniu Zhang, Bin Li, Yun Zhou, Fengxuan Han, Yong Wang   +15 more
wiley   +1 more source

Ultrastructural characteristics of the synovial membrane in osteoarthritic temporomandibular joints

, 1997
Purpose: This study analyzed the ultrastructural characteristics of the synovial membrane in various stages of osteoarthritis (OA) of the temporomandibular joint (TMJ), and developed a classification of this involvement based on these morphologic ...
Dijkgraaf, LC, Liem, RSB, deBont, LGM
core   +1 more source

Synovial Membrane Tumors of Joints [PDF]

The American Journal of the Medical Sciences, 1922
n ...
openaire   +2 more sources

Temporomandibular joint biomechanical restrictions: The fluid and synovial membrane

, 1999
The authors analyze the functions of the synovial membrane and the chemical-physical properties of synovial fluid. In particular they evaluate the role played by synovial fluid in the complex mechanism of the temporomandibular joint.
Francesco Fabiani, CASCONE, PIERO, Gianluca Nicolai, Stefano Vetrano   +3 more
core   +1 more source

Advances in Cancer Immunotherapy for Solid Tumors

Advanced Science, EarlyView.
Cancer immunotherapy for solid tumors is rapidly evolving beyond classical checkpoint blockade toward more precise strategies. Emerging checkpoint targets, bispecific antibodies, antibody–drug conjugate combinations, personalized vaccines, cellular therapies, and engineered cytokines are expanding therapeutic possibilities, while biomarker‐guided ...
Shira Gabizon‐Peretz, Harriet M. Kluger   +1 more
wiley   +1 more source

Synovial membrane immunohistology in early-untreated rheumatoid arthritis reveals high expression of catabolic bone markers that is modulated by methotrexate

Arthritis Research & Therapy, 2013
IntroductionWe aimed to investigate the expression and therapeutic modulation of the receptor activator of the NF-κB ligand (RANKL) system in early-untreated rheumatoid arthritis (RA).MethodsIn this study, 15 patients with newly diagnosed RA (median ...
S. Revu, P. Neregård, E. af Klint, M. Korotkova, A. Catrina   +4 more
semanticscholar   +1 more source

In vivo physiological changes in the synovial membrane of the knee during reperfusion after arthroscopy

, 2002
We have used in vivo microdialysis to monitor postoperative physiological events in the synovial membrane after arthroscopy. The levels of lactate were significantly higher in the synovial membrane than in the reference tissue (subcutaneous fat) and ...
L. Felländer-Tsai, T Wredmark, E. Högberg, P. Arner   +3 more
core   +1 more source