Results 61 to 70 of about 1,242,856 (294)

Synovial joints: Mechanobiology and tissue engineering of articular cartilage and synovial fluid [PDF]

, 2017
This chapter provides an overview of the components of synovial joints including articular cartilage, synovium, and synovial fluid. Focus is placed on the biomechanical properties of these tissues and models of their behavior.
Meinert, C., Sah, R.L., Klein, T.J., Raleigh, A.R., Chen, A.C., A.R. Raleigh, C. Meinert, McCarty, W.J., T.J. Klein, W.J. McCarty, A.C. Chen, R.L. Sah   +11 more
core   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Analysis of the subpopulation composition of immunocompetent cells in the synovial membrane and peripheral blood in relation to rheumatoid arthritis activity

Сибирский научный медицинский журнал
Rheumatoid arthritis (RA) is a chronic autoimmune disease that leads to irreversible structural joint damage and disability. Even with modern therapeutic approaches, a subset of patients continues to exhibit persistent inflammatory activity, which ...
V. O. Omelchenko, A. N. Danilova, A. A. Akimova, M. A. Karpov, V. S. Ovchinnikov, M. A. Korolev   +5 more
doaj   +1 more source

Effects of ultrasound therapy on the synovial fluid proteome in a rabbit surgery-induced model of knee osteoarthritis

BioMedical Engineering OnLine, 2019
Background Ultrasound (US) therapy may improve osteoarthritis symptoms. We investigated the effects of US on the synovial fluid (SF) proteome in a rabbit knee osteoarthritis (KOA) model to explore its therapeutic mechanisms.
Qinglu Luo, Shuangquan Ji, Zhimi Li, Tao Huang, Siqin Fan, Qin Xi   +5 more
doaj   +1 more source

Digoxin Alleviates Osteoarthritis by Inhibiting Macrophage Extracellular Trap Formation via Disruption of the LSP1‐SOD1 Interaction

Advanced Science, EarlyView.
Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan, Xinzhe Feng, Chuanju Liu, Jianfei Tong, Zhi Li, Chenxu Liu, Yutong Dong, Chen Meng, Yihong Xu, Weidong Xu   +9 more
wiley   +1 more source

Cytolytic activity in T cell clones derived from human synovial rheumatoid membrane: inhibition by synovial fluid

, 1990
Summary A panel of T cell clones was derived from the synovial membrane of a patient with rheumatoid arthritis (RA). We investigated whether T cell clones with cytolytic properties were present and whether T cell cytotoxicity was ...
A M M MILTENBURG, J M VAN LAAR, M R DAHA, P DE KUIPER, F C BREEDVELD   +4 more
core   +1 more source

Spatially Confined/Ligand‐Directed Ultrabright NIR‐AIE Nanoprobe for In Vitro Rapid Detection and In Situ Imaging of Bacterial Septic Arthritis

Advanced Science, EarlyView.
Inorganic PbS quantum dots spatially confine AIEgens and enable cooperative luminescence within a ligand‐directed core–shell–shell nanoassembly, generating ultrabright NIR PPANPs with enhanced fluorescence and photothermal performance. The platform enables 10‐min S.
Yujian Li, Jia Shu, Sijia Lv, Leilei Qin, Xuefeng Luo, PengCheng Xiao, Huan Cai, Xin Gao, Yan Zhao, Haotian Zhou, Yaji Yang, Zhenglin Zhu, Shijia Ding, Juan Li, Rui Chen, Wei Huang   +15 more
wiley   +1 more source

Acute Tuberculosis of Synovial Membrane [PDF]

The American Journal of the Medical Sciences, 1877
n ...
openaire   +2 more sources

Effect of Toll-Like Receptor 4 on Synovial Injury of Temporomandibular Joint in Rats Caused by Occlusal Interference

Mediators of Inflammation, 2016
Synovitis is an important disease that causes intractable pain in TMJ. Some investigations suggested that the increasing expression of IL-1β secreted by synovial lining cells plays an important role in synovial inflammation and cartilage destruction in ...
Jingjing Kong, Yingying Yang, Shuzhen Sun, Jianli Xie, Xuefen Lin, Ping Ji   +5 more
doaj   +1 more source

Synovial inflammation plays a greater role in post-traumatic osteoarthritis compared to idiopathic osteoarthritis in the Hartley guinea pig knee

BMC Musculoskeletal Disorders, 2017
Background The objective of this study was to evaluate the extent of stromal cell-derived factor-1’s (SDF-1) involvement in the pathogenesis of idiopathic versus post-traumatic OA by comparing differences in synovial membrane morphology, SDF-1 synovial ...
Nathan P. Thomas, Wesley J. Wu, Braden C. Fleming, Fangyuan Wei, Qian Chen, Lei Wei   +5 more
doaj   +1 more source